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A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

http://www.wikidata.org/entity/Q24669612

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Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination.BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway Stimulation of flap endonuclease-1 by the Bloom's syndrome protein FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network Identification of RecQL1 as a Holliday junction processing enzyme in human cell lines BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1 Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin Fanconi anemia complementation group A (FANCA) protein has intrinsic affinity for nucleic acids with preference for single-stranded forms How the fanconi anemia pathway guards the genome Tip60 is required for DNA interstrand cross-link repair in the Fanconi anemia pathway RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway Functions and regulation of the multitasking FANCM family of DNA motor proteins Structure and Cellular Roles of the RMI Core Complex from the Bloom Syndrome Dissolvasome Crystal structures of RMI1 and RMI2, two OB-fold regulatory subunits of the BLM complex Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3 A novel ubiquitin ligase is deficient in Fanconi anemia Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights The Fanconi anemia core complex forms four complexes of different sizes in different subcellular compartments Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins FANCC, FANCE, and FANCD2 form a ternary complex essential to the integrity of the Fanconi anemia DNA damage response pathway HES1 is a novel interactor of the Fanconi anemia core complex X-linked inheritance of Fanconi anemia complementation group B The broken genome: genetic and pharmacologic approaches to breaking DNA Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability Loss of RMI2 Increases Genome Instability and Causes a Bloom-Like Syndrome Expanded roles of the Fanconi anemia pathway in preserving genomic stability The Fanconi anemia pathway and ubiquitin A never-ending story: the steadily growing family of the FA and FA-like genes

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A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

http://www.wikidata.org/entity/Q24669612

description

2003 nî lūn-bûn

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2003 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

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A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

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A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

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A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

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A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

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A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

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A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

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A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

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A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

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MCB.23.10.3417-3426.2003

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Molecular and Cellular Biology

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A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

@en

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Amom Ruhikanta Meetei

http://www.w3.org/2001/XMLSchema#string

Dafeng Yang

http://www.w3.org/2001/XMLSchema#string

Mary K Young

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Maureen E Hoatlin

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Michael Wallisch

http://www.w3.org/2001/XMLSchema#string

Salvatore Sechi

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Weidong Wang

http://www.w3.org/2001/XMLSchema#string

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Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome

Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells

Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity

The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG

The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex

The Bloom's syndrome gene product is a 3'-5' DNA helicase

The Bloom's syndrome gene product is homologous to RecQ helicases

Diversity and specialization of mammalian SWI/SNF complexes

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10.1128/MCB.23.10.3417-3426.2003

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