The mechanism of chromosomal translocation t(11;14) involving the T-cell receptor C delta locus on human chromosome 14q11 and a transcribed region of chromosome 11p15
about
TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemiaAn unusual structure of a putative T cell oncogene which allows production of similar proteins from distinct mRNAsThe tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix proteinT cell receptor gamma and delta rearrangements in hematologic malignancies. Relationship to lymphoid differentiationThe rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genesThe LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cellsSpecific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemiaThe t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger proteinUse of a variable alpha region to create a functional T-cell receptor delta chainConformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complexNovel genes for potential ligand-binding proteins in subregions of the olfactory mucosaDifferential splicing creates a diversity of transcripts from a neurospecific developmentally regulated gene encoding a protein with new zinc-finger motifsThymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphomaNull mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in miceGenomic organization of the human T-cell antigen-receptor alpha/delta locus.Human T-cell-receptor delta chain: genomic organization, diversity, and expression in populations of cells.Clustering of breakpoints on chromosome 10 in acute T-cell leukemias with the t(10;14) chromosome translocationThe LIM domain gene LMO4 inhibits differentiation of mammary epithelial cells in vitro and is overexpressed in breast cancer.Recombinative events of the T cell antigen receptor delta gene in peripheral T cell lymphomasGenomic donor cassette sharing during VLRA and VLRC assembly in jawless vertebratesOverexpression Beadex mutations and loss-of-function heldup-a mutations in Drosophila affect the 3' regulatory and coding components, respectively, of the Dlmo gene.Cysteine-rich LIM domains of LIM-homeodomain and LIM-only proteins contain zinc but not iron.Localization of the human angiogenin gene to chromosome band 14q11, proximal to the T cell receptor alpha/delta locusThe LMO2 -25 Region Harbours GATA2-Dependent Myeloid Enhancer and RUNX-Dependent T-Lymphoid Repressor Activity.Regulated expression and structure of T cell receptor gamma/delta transcripts in human thymic ontogenyThe chromosome translocation (11;14)(p13;q11) associated with T cell acute leukemia. Asymmetric diversification of the translocational junctions.The V gamma locus of the human T cell receptor gamma gene. Repertoire polymorphism of the first variable gene segment subgroup.Diversity and organization of human T cell receptor delta variable gene segments.Consistent breakage between consensus recombinase heptamers of chromosome 9 DNA in a recurrent chromosomal translocation of human T cell leukemia.Demonstration of delta rec-pseudo J alpha rearrangement with deletion of the delta locus in a human stem-cell leukemia.T lymphomagenesis is determined by a dominant host gene thymic lymphoma susceptible mouse-1 (TLSM-1) in mouse models.Transcription and cancer.Zyxin and cCRP: two interactive LIM domain proteins associated with the cytoskeletonAssessing the pathogenic potential of the V(D)J recombinase by interlocus immunoglobulin light-chain gene rearrangementCryptic signals and the fidelity of V(D)J joining.Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target.Molecular involvement of the pvt-1 locus in a gamma/delta T-cell leukemia bearing a variant t(8;14)(q24;q11) translocation.Bivalent promoter marks and a latent enhancer may prime the leukaemia oncogene LMO1 for ectopic expression in T-cell leukaemia.LMO2 is a novel predictive marker for a better prognosis in pancreatic cancer.
P2860
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P2860
The mechanism of chromosomal translocation t(11;14) involving the T-cell receptor C delta locus on human chromosome 14q11 and a transcribed region of chromosome 11p15
description
1988 nî lūn-bûn
@nan
1988 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
The mechanism of chromosomal t ...... bed region of chromosome 11p15
@ast
The mechanism of chromosomal t ...... bed region of chromosome 11p15
@en
The mechanism of chromosomal t ...... bed region of chromosome 11p15
@nl
type
label
The mechanism of chromosomal t ...... bed region of chromosome 11p15
@ast
The mechanism of chromosomal t ...... bed region of chromosome 11p15
@en
The mechanism of chromosomal t ...... bed region of chromosome 11p15
@nl
prefLabel
The mechanism of chromosomal t ...... bed region of chromosome 11p15
@ast
The mechanism of chromosomal t ...... bed region of chromosome 11p15
@en
The mechanism of chromosomal t ...... bed region of chromosome 11p15
@nl
P2093
P2860
P1433
P1476
The mechanism of chromosomal t ...... bed region of chromosome 11p15
@en
P2093
J J Waters
T H Rabbitts
P2860
P304
P407
P577
1988-02-01T00:00:00Z