Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase
about
The small GTPase RalA targets filamin to induce filopodiaActivated Ras interacts with the Ral guanine nucleotide dissociation stimulatorThe multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domainsMNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substratesDistinct roles of RalA and RalB in the progression of cytokinesis are supported by distinct RalGEFs.Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPasesActivation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells.Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformationIdentification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and RapInteraction of activated Ras with Raf-1 alone may be sufficient for transformation of rat2 cellsStructural study of the Cdc25 domain from Ral-specific guanine-nucleotide exchange factor RalGPS1aAssociation of Rab25 and Rab11a with the apical recycling system of polarized Madin-Darby canine kidney cellsAberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanismsCellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)Identification of recurrent regions of chromosome loss and gain in vestibular schwannomas using comparative genomic hybridisation.Regulation of RasGRP via a phorbol ester-responsive C1 domain.Ral is both necessary and sufficient for the inhibition of myeloid differentiation mediated by RasDifferential roles of Akt, Rac, and Ral in R-Ras-mediated cellular transformation, adhesion, and survival.Independent and coordinate effects of ADP-ribosyltransferase and GTPase-activating activities of exoenzyme S on HT-29 epithelial cell function.Ral small GTPase signaling and oncogenesis: More than just 15minutes of fameThe RalGEF-Ral Effector Signaling Network: The Road Less Traveled for Anti-Ras Drug Discovery.The Drosophila Ral GTPase regulates developmental cell shape changes through the Jun NH(2)-terminal kinase pathway.GTPase-dependent signaling in bacteria: characterization of a membrane-binding site for era in Escherichia coli.Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation.Rap2a serves as a potential prognostic indicator of renal cell carcinoma and promotes its migration and invasion through up-regulating p-Akt.The secret life of kinases: functions beyond catalysisDifferential effects of protein kinase A on Ras effector pathwaysActivation of the small GTPase Ral in platelets.ralGDS family members interact with the effector loop of ras p21.The human Rgr oncogene is overexpressed in T-cell malignancies and induces transformation by acting as a GEF for Ras and Ral.RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer.RALA exchanges GDP for GTPRas-related protein Rap2c promotes the migration and invasion of human osteosarcoma cells.Role of oocyte-specific genes in the development of mammalian embryos.
P2860
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P2860
Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase
description
1993 nî lūn-bûn
@nan
1993 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase
@ast
Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase
@en
Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase
@nl
type
label
Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase
@ast
Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase
@en
Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase
@nl
prefLabel
Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase
@ast
Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase
@en
Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase
@nl
P2093
P2860
P1433
P1476
Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase
@en
P2093
P2860
P304
P407
P577
1993-01-01T00:00:00Z