Regulation of RasGRP via a phorbol ester-responsive C1 domain.
about
Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3Characterization of RasGRP2, a plasma membrane-targeted, dual specificity Ras/Rap exchange factorIdentification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interactionRasGRP4 is a novel Ras activator isolated from acute myeloid leukemiaDirect demonstration of involvement of protein kinase Calpha in the Ca2+-induced platelet aggregationPhospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1Characterization of the Rac-GAP (Rac-GTPase-activating protein) activity of beta2-chimaerin, a 'non-protein kinase C' phorbol ester receptorRas-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of RafA vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol estersThe Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling propertiesDiacylglycerol kinase zeta regulates Ras activation by a novel mechanismRasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responsesThe role and regulation of mTOR in T-lymphocyte functionRas superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?The Immunomodulatory Functions of Diacylglycerol Kinase ζRegulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zetaLAT, the linker for activation of T cells: a bridge between T cell-specific and general signaling pathwaysThe neurofibromatosis type 1 (Nf1) tumor suppressor is a modifier of carcinogen-induced pigmentation and papilloma formation in C57BL/6 miceInositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activityThe NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeatsRasGRP is essential for mouse thymocyte differentiation and TCR signalingRas history: The saga continues.Identification of a Ras GTPase-activating protein regulated by receptor-mediated Ca2+ oscillations.Identification and characterization of an activating TrkA deletion mutation in acute myeloid leukemia.Regulation of RasGRP1 function in T cell development and activation by its unique tail domain.Sites of phosphorylation by protein kinase A in CDC25Mm/GRF1, a guanine nucleotide exchange factor for Ras.The use of knockout mice reveals a synergistic role of the Vav1 and Rasgrf2 gene deficiencies in lymphomagenesis and metastasisHyperactive Ras as a therapeutic target in neurofibromatosis type 1.Amphitropic proteins: regulation by reversible membrane interactions (review).The frequencies of calcium oscillations are optimized for efficient calcium-mediated activation of Ras and the ERK/MAPK cascade.The ζ isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling.Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters.The Gab1 docking protein links the b cell antigen receptor to the phosphatidylinositol 3-kinase/Akt signaling pathway and to the SHP2 tyrosine phosphatase.Diacylglycerol kinase ζ limits B cell antigen receptor-dependent activation of ERK signaling to inhibit early antibody responsesZap-70-independent Ca(2+) mobilization and Erk activation in Jurkat T cells in response to T-cell antigen receptor ligation.RasGRP3 contributes to formation and maintenance of the prostate cancer phenotype.Diacylglycerols containing Omega 3 and Omega 6 fatty acids bind to RasGRP and modulate MAP kinase activation.Targeted disruption of Ras-Grf2 shows its dispensability for mouse growth and development.Membrane targeting by C1 and C2 domains.Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.
P2860
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P2860
Regulation of RasGRP via a phorbol ester-responsive C1 domain.
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Regulation of RasGRP via a phorbol ester-responsive C1 domain.
@ast
Regulation of RasGRP via a phorbol ester-responsive C1 domain.
@en
type
label
Regulation of RasGRP via a phorbol ester-responsive C1 domain.
@ast
Regulation of RasGRP via a phorbol ester-responsive C1 domain.
@en
prefLabel
Regulation of RasGRP via a phorbol ester-responsive C1 domain.
@ast
Regulation of RasGRP via a phorbol ester-responsive C1 domain.
@en
P2093
P2860
P356
P1476
Regulation of RasGRP via a phorbol ester-responsive C1 domain
@en
P2093
P2860
P304
P356
10.1128/MCB.18.12.6995
P407
P577
1998-12-01T00:00:00Z