PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans - Wikidata - wikimedia - TriplyDB

PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans

PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans

http://www.wikidata.org/entity/Q24595214

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Transmission distortion affecting human noncrossover but not crossover recombination: a hidden source of meiotic drive Fine characterisation of a recombination hotspot at the DPY19L2 locus and resolution of the paradoxical excess of duplications over deletions in the general population Recombination modulates how selection affects linked sites in Drosophila Variants of the protein PRDM9 differentially regulate a set of human meiotic recombination hotspots highly active in African populations Genome-wide analysis reveals novel molecular features of mouse recombination hotspots Mechanisms underlying structural variant formation in genomic disorders Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family New paradigms for conserved, multifactorial, cis-acting regulation of meiotic recombination Insights into female germ cell biology: from in vivo development to in vitro derivations Chromosomal translocations and palindromic AT-rich repeats The Meiotic Recombination Activator PRDM9 Trimethylates Both H3K36 and H3K4 at Recombination Hotspots In Vivo Multimer Formation Explains Allelic Suppression of PRDM9 Recombination Hotspots Variation in genome-wide levels of meiotic recombination is established at the onset of prophase in mammalian males Genetic analysis of genome-scale recombination rate evolution in house mice Structural variation mutagenesis of the human genome: Impact on disease and evolution.Meiotic DSB patterning: A multifaceted process Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly Mouse PRDM9 DNA-binding specificity determines sites of histone H3 lysine 4 trimethylation for initiation of meiotic recombination The pioneering role of PRDM9 indel mutations in tarsier evolution Stable recombination hotspots in birds Scale matters: the spatial correlation of yeast meiotic DNA breaks with histone H3 trimethylation is driven largely by independent colocalization at promoters Prdm9, a major determinant of meiotic recombination hotspots, is not functional in dogs and their wild relatives, wolves and coyotes Variation in human recombination rates and its genetic determinants Distribution of recombination hotspots in the human genome--a comparison of computer simulations with real data A New Metazoan Recombination Rate Record and Consistently High Recombination Rates in the Honey Bee Genus Apis Accompanied by Frequent Inversions but Not Translocations Primate evolution of the recombination regulator PRDM9 The landscape of recombination in African Americans.A pipeline for local assembly of minisatellite alleles from single-molecule sequencing data.Diversity of Prdm9 zinc finger array in wild mice unravels new facets of the evolutionary turnover of this coding minisatellite The 8p23 inversion polymorphism determines local recombination heterogeneity across human populations PRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration.High-resolution sex-specific linkage maps of the mouse reveal polarized distribution of crossovers in male germline The long zinc finger domain of PRDM9 forms a highly stable and long-lived complex with its DNA recognition sequence.Meiotic recombination analyses of individual chromosomes in male domestic pigs (Sus scrofa domestica).Intraspecific variation of recombination rate in maize.DNA binding specificities of the long zinc-finger recombination protein PRDM9.An examination of the relationship between hotspots and recombination associated with chromosome 21 nondisjunction Prdm9 polymorphism unveils mouse evolutionary tracks.The Drosophila zinc finger protein trade embargo is required for double strand break formation in meiosis Recombination in the human Pseudoautosomal region PAR1.

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PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans

http://www.wikidata.org/entity/Q24595214

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

PRDM9 variation strongly influ ...... meiotic instability in humans

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PRDM9 variation strongly influ ...... meiotic instability in humans

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PRDM9 variation strongly influ ...... meiotic instability in humans

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type

label

PRDM9 variation strongly influ ...... meiotic instability in humans

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PRDM9 variation strongly influ ...... meiotic instability in humans

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PRDM9 variation strongly influ ...... meiotic instability in humans

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prefLabel

PRDM9 variation strongly influ ...... meiotic instability in humans

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PRDM9 variation strongly influ ...... meiotic instability in humans

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PRDM9 variation strongly influ ...... meiotic instability in humans

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Nature Genetics

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PRDM9 variation strongly influ ...... meiotic instability in humans

@en

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Alec J Jeffreys

http://www.w3.org/2001/XMLSchema#string

Ingrid L Berg

http://www.w3.org/2001/XMLSchema#string

Kwan-Wood G Lam

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Rita Neumann

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Shriparna Sarbajna

http://www.w3.org/2001/XMLSchema#string

P2860

Prdm9 controls activation of mammalian recombination hotspots

A second generation human haplotype map of over 3.1 million SNPs

A histone H3 methyltransferase controls epigenetic events required for meiotic prophase

Origins and functional impact of copy number variation in the human genome

Linkage disequilibrium in the human genome

DNA recognition by Cys2His2 zinc finger proteins

Genetic analysis of variation in human meiotic recombination.

Two modes of germline instability at human minisatellite MS1 (locus D1S7): complex rearrangements and paradoxical hyperdeletion.

PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice

Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination

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859-63

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scholarly article

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359298

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10.1038/NG.658

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10

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42

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Linda Odenthal-Hesse

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2010-10-01T00:00:00Z

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46149745

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1011264677

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20818382

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3092422

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