The Meiotic Recombination Activator PRDM9 Trimethylates Both H3K36 and H3K4 at Recombination Hotspots In Vivo
about
The long zinc finger domain of PRDM9 forms a highly stable and long-lived complex with its DNA recognition sequence.Repeated losses of PRDM9-directed recombination despite the conservation of PRDM9 across vertebratesPRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosisX-Chromosome Control of Genome-Scale Recombination Rates in House MiceIn vivo binding of PRDM9 reveals interactions with noncanonical genomic sites.Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hot Spots.Multifunctional Involvement of a C2H2 Zinc Finger Protein (PbZfp) in Malaria Transmission, Histone Modification, and Susceptibility to DNA Damage ResponseGenomic and chromatin features shaping meiotic double-strand break formation and repair in mice.The consequences of sequence erosion in the evolution of recombination hotspots.The PRDM9 KRAB domain is required for meiosis and involved in protein interactions.A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis.The Role of KRAB-ZFPs in Transposable Element Repression and Mammalian Evolution.MORC2B is essential for meiotic progression and fertility.PRDM9 and Its Role in Genetic Recombination.Modulation of Prdm9-controlled meiotic chromosome asynapsis overrides hybrid sterility in mice.Nucleosomes and DNA methylation shape meiotic DSB frequency in Arabidopsis thaliana transposons and gene regulatory regions.Interrogating the Functions of PRDM9 Domains in Meiosis.The impact of recombination on human mutation load and disease.Control of meiotic double-strand-break formation by ATM: local and global viewsChromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspotHistone Methyltransferase mRNA Levels Increase in Response to Curative Hormone Treatment for Cryptorchidism-Dependent Male Infertility
P2860
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P2860
The Meiotic Recombination Activator PRDM9 Trimethylates Both H3K36 and H3K4 at Recombination Hotspots In Vivo
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2016 nî lūn-bûn
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2016 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2016 թվականի հունիսին հրատարակված գիտական հոդված
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2016年の論文
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2016年論文
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2016年論文
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2016年論文
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2016年論文
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2016年論文
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2016年论文
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name
The Meiotic Recombination Acti ...... Recombination Hotspots In Vivo
@ast
The Meiotic Recombination Acti ...... Recombination Hotspots In Vivo
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The Meiotic Recombination Acti ...... Recombination Hotspots In Vivo
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label
The Meiotic Recombination Acti ...... Recombination Hotspots In Vivo
@ast
The Meiotic Recombination Acti ...... Recombination Hotspots In Vivo
@en
The Meiotic Recombination Acti ...... Recombination Hotspots In Vivo
@nl
prefLabel
The Meiotic Recombination Acti ...... Recombination Hotspots In Vivo
@ast
The Meiotic Recombination Acti ...... Recombination Hotspots In Vivo
@en
The Meiotic Recombination Acti ...... Recombination Hotspots In Vivo
@nl
P2093
P2860
P3181
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The Meiotic Recombination Acti ...... Recombination Hotspots In Vivo
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P2093
Christopher L Baker
Kenneth Paigen
Michael Walker
Petko M Petkov
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1006146
P407
P577
2016-06-01T00:00:00Z