SUMO modification of a novel MAR-binding protein, SATB2, modulates immunoglobulin mu gene expression
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Small deletions of SATB2 cause some of the clinical features of the 2q33.1 microdeletion syndromeAltered DNA methylation in leukocytes with trisomy 21Sumoylation delays the ATF7 transcription factor subcellular localization and inhibits its transcriptional activitySATB2 augments ΔNp63α in head and neck squamous cell carcinomaSUMO conjugation to the matrix attachment region-binding protein, special AT-rich sequence-binding protein-1 (SATB1), targets SATB1 to promyelocytic nuclear bodies where it undergoes caspase cleavageInhibition of DNA binding by differential sumoylation of heat shock factors.NXP-2 association with SUMO-2 depends on lysines required for transcriptional repressionTesting reported associations of genetic risk factors for oral clefts in a large Irish study populationThe novel PIAS-like protein hZimp10 is a transcriptional co-activator of the p53 tumor suppressorMicroRNA regulation in cancer-associated fibroblastsModeling ALS with motor neurons derived from human induced pluripotent stem cellsSAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cellsRegulation of gene-activation pathways by PIAS proteins in the immune systemRepression of the Transactivating Capacity of the Oncoprotein PLAG1 by SUMOylationSystematic identification and analysis of mammalian small ubiquitin-like modifier substratesEbola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinerySatb2 haploinsufficiency phenocopies 2q32-q33 deletions, whereas loss suggests a fundamental role in the coordination of jaw developmentSubnuclear cyclin D3 compartments and the coordinated regulation of proliferation and immunoglobulin variable gene repressionSUMO and Chromatin Remodeling.The role of miR-31 and its target gene SATB2 in cancer-associated fibroblasts.Acetylation-dependent interaction of SATB1 and CtBP1 mediates transcriptional repression by SATB1.A weakened transcriptional enhancer yields variegated gene expressionIn vivo modeling of polysumoylation uncovers targeting of Topoisomerase II to the nucleolus via optimal level of SUMO modificationControlling hematopoiesis through sumoylation-dependent regulation of a GATA factor.microRNA-182 targets special AT-rich sequence-binding protein 2 to promote colorectal cancer proliferation and metastasis.Expression of SATB1 promotes the growth and metastasis of colorectal cancer.Displacement of SATB1-bound histone deacetylase 1 corepressor by the human immunodeficiency virus type 1 transactivator induces expression of interleukin-2 and its receptor in T cells.The DEAD-box protein DP103 (Ddx20 or Gemin-3) represses orphan nuclear receptor activity via SUMO modification.Phosphorylation-dependent interaction of SATB1 and PIAS1 directs SUMO-regulated caspase cleavage of SATB1.Array-CGH analysis in Rwandan patients presenting development delay/intellectual disability with multiple congenital anomalies.Disorders with similar clinical phenotypes reveal underlying genetic interaction: SATB2 acts as an activator of the UPF3B gene.Decreased expression of SATB2: a novel independent prognostic marker of worse outcome in laryngeal carcinoma patients.Prognostic and treatment predictive significance of SATB1 and SATB2 expression in pancreatic and periampullary adenocarcinoma.The novel PIAS-like protein hZimp10 enhances Smad transcriptional activity.Bmp and Shh signaling mediate the expression of satb2 in the pharyngeal arches.A cross-species analysis of Satb2 expression suggests deep conservation across vertebrate lineages.Critical-size calvarial bone defects healing in a mouse model with silk scaffolds and SATB2-modified iPSCsRoles of SATB2 in osteogenic differentiation and bone regenerationElevated microRNA-31 expression regulates colorectal cancer progression by repressing its target gene SATB2Prognostic value of SATB2 expression in patients with esophageal squamous cell carcinoma.
P2860
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P2860
SUMO modification of a novel MAR-binding protein, SATB2, modulates immunoglobulin mu gene expression
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
SUMO modification of a novel M ...... unoglobulin mu gene expression
@ast
SUMO modification of a novel M ...... unoglobulin mu gene expression
@en
SUMO modification of a novel M ...... unoglobulin mu gene expression
@nl
type
label
SUMO modification of a novel M ...... unoglobulin mu gene expression
@ast
SUMO modification of a novel M ...... unoglobulin mu gene expression
@en
SUMO modification of a novel M ...... unoglobulin mu gene expression
@nl
prefLabel
SUMO modification of a novel M ...... unoglobulin mu gene expression
@ast
SUMO modification of a novel M ...... unoglobulin mu gene expression
@en
SUMO modification of a novel M ...... unoglobulin mu gene expression
@nl
P2860
P3181
P356
P1433
P1476
SUMO modification of a novel M ...... unoglobulin mu gene expression
@en
P2093
Julia Dambacher
Rudolf Grosschedl
P2860
P304
P3181
P356
10.1101/GAD.1153003
P407
P577
2003-12-15T00:00:00Z