Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice
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Humanin, a cytoprotective peptide, is expressed in carotid atherosclerotic [corrected] plaques in humansThe emerging role of the mitochondrial-derived peptide humanin in stress resistanceHumanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient miceMOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolismSH3-binding protein 5 mediates the neuroprotective effect of the secreted bioactive peptide humanin by inhibiting c-Jun NH2-terminal kinaseHumanin: a harbinger of mitochondrial-derived peptides?Diminished mTOR signaling: a common mode of action for endocrine longevity factors.Humanin and age-related diseases: a new link?Humanin binds MPP8: mapping interaction sites of the peptide and protein.Central effects of humanin on hepatic triglyceride secretion.Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline.Secreted calmodulin-like skin protein inhibits neuronal death in cell-based Alzheimer's disease models via the heterotrimeric Humanin receptorCirculating humanin levels are associated with preserved coronary endothelial functionPharmacokinetics and tissue distribution of humanin and its analogues in male rodents.Endocrine protection of ischemic myocardium by FGF21 from the liver and adipose tissue.Potent humanin analog increases glucose-stimulated insulin secretion through enhanced metabolism in the β cell.The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus.Humanin skeletal muscle protein levels increase after resistance training in men with impaired glucose metabolism.Effects of humanin on experimental colitis induced by 2,4,6-trinitrobenzene sulphonic acid in rats.Protective effects of Humanin and calmodulin-like skin protein in Alzheimer's disease and broad range of abnormalities.Trans-system mechanisms against ischemic myocardial injury.Mitochondrial Retrograde Signaling: Triggers, Pathways, and Outcomes.Humanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage.Potential Roles of Humanin on Apoptosis in the Heart.Humanin: Functional Interfaces with IGF-I.Mitochondrially derived peptides as novel regulators of metabolism.The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction.Humanin protects against chemotherapy-induced stage-specific male germ cell apoptosis in rats.Protective Mechanisms of the Mitochondrial-Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells.The cytoprotective peptide humanin is induced and neutralizes Bax after pro-apoptotic stress in the rat testis.A humanin analog decreases oxidative stress and preserves mitochondrial integrity in cardiac myoblasts.The effects of humanin and its analogues on male germ cell apoptosis induced by chemotherapeutic drugs.Humanin analogue, S14G-humanin, has neuroprotective effects against oxygen glucose deprivation/reoxygenation by reactivating Jak2/Stat3 signaling through the PI3K/AKT pathwayIn vivo monitoring of venous thrombosis in mice.Humanin exerts cardioprotection against cardiac ischemia/reperfusion injury through attenuation of mitochondrial dysfunction.Humanin is an endogenous activator of chaperone-mediated autophagy.High-dose Humanin analogue applied during ischemia exerts cardioprotection against ischemia/reperfusion injury by reducing mitochondrial dysfunction.Serum humanin concentrations in women with pre-eclampsia compared to women with uncomplicated pregnancies.Cardiomyocyte Specific Deletion of Sirt1 Gene Sensitizes Myocardium to Ischemia and Reperfusion Injury.Infrared fluorescence for vascular barrier breach in vivo--a novel method for quantitation of albumin efflux.
P2860
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P2860
Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice
@ast
Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice
@en
Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice
@nl
type
label
Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice
@ast
Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice
@en
Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice
@nl
prefLabel
Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice
@ast
Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice
@en
Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice
@nl
P2093
P2860
P3181
P1476
Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice
@en
P2093
Anjana Nemkal
Benjamin L Predmore
David J Lefer
Derek M Huffman
Laura Klein
Lingguang Cui
Madhav Lavu
Radhika H Muzumdar
Sang Yong Ji
Saurabh Jha
P2860
P304
P3181
P356
10.1161/ATVBAHA.110.205997
P407
P577
2010-10-01T00:00:00Z