No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis - Wikidata - wikimedia - TriplyDB

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

http://www.wikidata.org/entity/Q24617359

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Warburg effect and translocation-induced genomic instability: two yeast models for cancer cells Pyruvate Kinase M2: A Potential Target for Regulating Inflammation The sweet trap in tumors: aerobic glycolysis and potential targets for therapy Dysregulated metabolism contributes to oncogenesis Pyruvate kinase M2 at a glance M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation.The HK2 Dependent "Warburg Effect" and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate Epithelial cancers in the post-genomic era: should we reconsider our lifestyle?Synergistic combination of gemcitabine and dietary molecule induces apoptosis in pancreatic cancer cells and down regulates PKM2 expression Mitochondria and cancer Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells.Analysis and interpretation of transcriptomic data obtained from extended Warburg effect genes in patients with clear cell renal cell carcinoma.Impact of Autoantibodies against Glycolytic Enzymes on Pathogenicity of Autoimmune Retinopathy and Other Autoimmune Disorders Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolism.Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells From genotype to functional phenotype: unraveling the metabolomic features of colorectal cancer.Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways PET imaging of tumor glycolysis downstream of hexokinase through noninvasive measurement of pyruvate kinase M2.Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma.Secreted human adipose leptin decreases mitochondrial respiration in HCT116 colon cancer cells.Organ-specific PTB1-associated microRNAs determine expression of pyruvate kinase isoforms.A novel pyruvate kinase M2 activator compound that suppresses lung cancer cell viability under hypoxia Isoform switch of pyruvate kinase M1 indeed occurs but not to pyruvate kinase M2 in human tumorigenesis.Phosphorylation of pyruvate kinase M2 and lactate dehydrogenase A by fibroblast growth factor receptor 1 in benign and malignant thyroid tissue.The return of metabolism: biochemistry and physiology of the pentose phosphate pathway Targeting glucose metabolism for cancer therapy.Protein Co-Expression Analysis as a Strategy to Complement a Standard Quantitative Proteomics Approach: Case of a Glioblastoma Multiforme Study.Emerging roles of PKM2 in cell metabolism and cancer progression Manipulation of PK-M mutually exclusive alternative splicing by antisense oligonucleotides Anticancer agents that counteract tumor glycolysis.PKLR promotes colorectal cancer liver colonization through induction of glutathione synthesis.Targeted Proteomics to Assess the Response to Anti-Angiogenic Treatment in Human Glioblastoma (GBM).Altered energy metabolism in cancer: a unique opportunity for therapeutic intervention.Recent discoveries in the cycling, growing and aging of the p53 field Extracellular PKM2 induces cancer proliferation by activating the EGFR signaling pathway.Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2.Cancer metabolism meets systems biology: Pyruvate kinase isoform PKM2 is a metabolic master regulator.Knockdown of the M2 Isoform of Pyruvate Kinase (PKM2) with shRNA Enhances the Effect of Docetaxel in Human NSCLC Cell Lines In Vitro.Nuclear PKM2 regulates the Warburg effect.

P2860

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P2860

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

http://www.wikidata.org/entity/Q24617359

description

2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

@ast

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

@en

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

@nl

type

label

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

@ast

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

@en

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

@nl

prefLabel

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

@ast

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

@en

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

@nl

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No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

@en

P2093

Barbara Kofler

http://www.w3.org/2001/XMLSchema#string

Katharina Bluemlein

http://www.w3.org/2001/XMLSchema#string

Nana-Maria Grüning

http://www.w3.org/2001/XMLSchema#string

René G Feichtinger

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P2860

Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling"

Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS

Pyruvate kinase M2 is a phosphotyrosine-binding protein

On the Origin of Cancer Cells

Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds

Pyruvate kinase type M2 and its role in tumor growth and spreading

Cancer cell metabolism: Warburg and beyond

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Mitochondrial free radical generation, oxidative stress, and aging

A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction.

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10.18632/ONCOTARGET.278

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21789790

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3248187

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