Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma. - Wikidata - wikimedia - TriplyDB

Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma.

Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma.

http://www.wikidata.org/entity/Q34603709

about

Non-invasive metabolic imaging of brain tumours in the era of precision medicine.Comparative Proteomic Analysis of Tumor Mesenchymal-Like Stem Cells Derived from High Grade versus Low Grade Gliomas Chaetocin-induced ROS-mediated apoptosis involves ATM-YAP1 axis and JNK-dependent inhibition of glucose metabolism Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolism.Organ-specific PTB1-associated microRNAs determine expression of pyruvate kinase isoforms.Proteomic profiling of high risk medulloblastoma reveals functional biology Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype.Metabolomic signature of brain cancer.Monoamine oxidase B levels are highly expressed in human gliomas and are correlated with the expression of HiF-1α and with transcription factors Sp1 and Sp3.EGFR-dependent mechanisms in glioblastoma: towards a better therapeutic strategy.Metabolic reprogramming in glioblastoma: the influence of cancer metabolism on epigenetics and unanswered questions The Role of Pyruvate Kinase M2 in Cancer Metabolism.Cancer stem cell molecular reprogramming of the Warburg effect in glioblastomas: a new target gleaned from an old concept.PKM2 uses control of HuR localization to regulate p27 and cell cycle progression in human glioblastoma cells.Changes in pyruvate metabolism detected by magnetic resonance imaging are linked to DNA damage and serve as a sensor of temozolomide response in glioblastoma cells.Bioenergetic Impairment in Animal and Cellular Models of Alzheimer's Disease: PARP-1 Inhibition Rescues Metabolic Dysfunctions.Pyruvate Kinase Muscle Isoenzyme 2 (PKM2) Expression Is Associated with Overall Survival in Pancreatic Ductal Adenocarcinoma.NOX4 functions as a mitochondrial energetic sensor coupling cancer metabolic reprogramming to drug resistance.A composite network of conserved and tissue specific gene interactions reveals possible genetic interactions in glioma.Hypoxia and oxygenation induce a metabolic switch between pentose phosphate pathway and glycolysis in glioma stem-like cells.Pkm2 can enhance pluripotency in ESCs and promote somatic cell reprogramming to iPSCs.Mutant IDH1 disrupts PKM2-β-catenin-BRG1 transcriptional network driven CD47 expression.Up-Regulation of PKM2 Relates to Retinal Ganglion Cell Apoptosis After Light-Induced Retinal Damage in Adult Rats.Metabolic Reprogramming in Thyroid Carcinoma.Antagonistic role of GSK3 isoforms in glioma survival.

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Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma.

http://www.wikidata.org/entity/Q34603709

description

2013 nî lūn-bûn

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2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2013 թվականի փետրվարին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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name

Pyruvate kinase M2 expression, ...... ecific manner in human glioma.

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Pyruvate kinase M2 expression, ...... ecific manner in human glioma.

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Pyruvate kinase M2 expression, ...... ecific manner in human glioma.

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Pyruvate kinase M2 expression, ...... ecific manner in human glioma.

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Pyruvate kinase M2 expression, ...... ecific manner in human glioma.

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Joanna J Phillips

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John Wiencke

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Joydeep Mukherjee

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Russell O Pieper

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P2860

Effects of the human papilloma virus HPV-16 E7 oncoprotein on glycolysis and glutaminolysis: role of pyruvate kinase type M2 and the glycolytic-enzyme complex

Understanding the Warburg effect: the metabolic requirements of cell proliferation

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

Human pyruvate kinase M2: a multifunctional protein

IDH1 and IDH2 mutations in gliomas

On the Origin of Cancer Cells

Pyruvate kinase type M2 and its role in tumor growth and spreading

Cancer cell metabolism: Warburg and beyond

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes

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