about
Frizzled7 as an emerging target for cancer therapyWNT signaling in bone development and homeostasisStructure and function of Norrin in assembly and activation of a Frizzled 4-Lrp5/6 complexWnt signaling in bone and muscleLRP5 and LRP6 in development and diseaseNiclosamide suppresses cancer cell growth by inducing Wnt co-receptor LRP6 degradation and inhibiting the Wnt/β-catenin pathwaySclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathwayPharmacological management of osteogenesis.Striking the target in Wnt-y conditions: intervening in Wnt signaling during cancer progressionSOST and DKK: Antagonists of LRP Family Signaling as Targets for Treating Bone Disease.Receptor heterodimerization as a novel mechanism for the regulation of Wnt/β-catenin signaling.A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice.Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5).The expanding role of Wnt signaling in bone metabolism.Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism.LRP receptor family member associated bone diseaseβ-catenin is selectively required for the expansion and regeneration of mature pancreatic acinar cells in mice.Wntless functions in mature osteoblasts to regulate bone mass.Sclerostin inhibits osteoblast differentiation without affecting BMP2/SMAD1/5 or Wnt3a/β-catenin signaling but through activation of platelet-derived growth factor receptor signaling in vitroWnt signaling in bone development and disease: making stronger bone with WntsCripto-1 enhances the canonical Wnt/β-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors.Wnt/β-catenin Signaling in Normal and Cancer Stem Cells.Skeletal metastasis: treatments, mouse models, and the Wnt signaling.Integration of cellular adhesion and Wnt signaling: Interactions between N-cadherin and LRP5 and their role in regulating bone mass.Lipoprotein receptor-related protein-6 protects the brain from ischemic injuryWnt and the Wnt signaling pathway in bone development and disease.Wnt pathway antagonists and angiogenesis.Drug discovery approaches to target Wnt signaling in cancer stem cells.Dissecting Major Signaling Pathways throughout the Development of Prostate Cancer.Developing siRNA therapies to address osteoporosisLocal inhibition of 5-lipoxygenase enhances bone formation in a rat model.Structural architecture and functional evolution of Wnts
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Wnt modulators in the biotech pipeline
@ast
Wnt modulators in the biotech pipeline
@en
Wnt modulators in the biotech pipeline
@nl
type
label
Wnt modulators in the biotech pipeline
@ast
Wnt modulators in the biotech pipeline
@en
Wnt modulators in the biotech pipeline
@nl
prefLabel
Wnt modulators in the biotech pipeline
@ast
Wnt modulators in the biotech pipeline
@en
Wnt modulators in the biotech pipeline
@nl
P2860
P356
P1476
Wnt modulators in the biotech pipeline
@en
P2093
Debra L Ellies
Jean-Philippe Rey
P2860
P304
P356
10.1002/DVDY.22181
P407
P577
2010-01-01T00:00:00Z