Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway - Wikidata - wikimedia - TriplyDB

Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway

Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway

http://www.wikidata.org/entity/Q31032805

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Sclerostin Antibody Therapy for the Treatment of Osteoporosis: Clinical Prospects and Challenges Metformin revisited: Does this regulator of AMP-activated protein kinase secondarily affect bone metabolism and prevent diabetic osteopathy Sclerostin Inhibition in the Management of Osteoporosis From disease to treatment: from rare skeletal disorders to treatments for osteoporosis Role of osteocytes in multiple myeloma bone disease Modulating Bone Resorption and Bone Formation in Opposite Directions in the Treatment of Postmenopausal Osteoporosis Parathyroid Hormone Induces Bone Cell Motility and Loss of Mature Osteocyte Phenotype through L-Calcium Channel Dependent and Independent Mechanisms A randomized, double-blind phase 2 clinical trial of blosozumab, a sclerostin antibody, in postmenopausal women with low bone mineral density Characterization of osteoblastic and osteolytic proteins in prostate cancer bone metastases.Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone.Inhibition of sclerostin in the management of osteoporosis: results of a phase 2 clinical trial meet expectations.Developments in sclerostin biology: regulation of gene expression, mechanisms of action, and physiological functions.Expression of fibroblast growth factor 23, vitamin D receptor, and sclerostin in bone tissue from hypercalciuric stone formers.The best of both worlds - managing the cancer, saving the bone.Deletion of a single β-catenin allele in osteocytes abolishes the bone anabolic response to loading A review of osteocyte function and the emerging importance of sclerostin Spinal Cord Injury and Osteoporosis: Causes, Mechanisms, and Rehabilitation Strategies HDAC5 controls MEF2C-driven sclerostin expression in osteocytes.Bone Loss Triggered by the Cytokine Network in Inflammatory Autoimmune Diseases.Connexin 43 deficiency desensitizes bone to the effects of mechanical unloading through modulation of both arms of bone remodeling Mechanical loading reduces inflammation-induced human osteocyte-to-osteoclast communication.Mechanical load increases in bone formation via a sclerostin-independent pathway.Heavy Metal Ion Regulation of Gene Expression: MECHANISMS BY WHICH LEAD INHIBITS OSTEOBLASTIC BONE-FORMING ACTIVITY THROUGH MODULATION OF THE Wnt/β-CATENIN SIGNALING PATHWAY.Sclerostin levels and bone turnover markers in adolescents with anorexia nervosa and healthy adolescent girls.Sclerostin Promotes Bone Remodeling in the Process of Tooth Movement.Osteocyte RANKL: new insights into the control of bone remodeling Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing osteoporosis Circulating sclerostin levels are decreased in patients with endogenous hypercortisolism and increase after treatment Osteocytes and Skeletal Pathophysiology Spinal cord injury-induced osteoporosis: pathogenesis and emerging therapies.The effects of bariatric surgery on bone and nephrolithiasis.Isolation and Functional Analysis of an Immortalized Murine Cementocyte Cell Line, IDG-CM6 Serum Sclerostin as an Independent Marker of Peripheral Arterial Stiffness in Renal Transplantation Recipients: A Cross-Sectional Study.Sclerostin is essential for alveolar bone loss in occlusal hypofunction The central nervous system (CNS)-independent anti-bone-resorptive activity of muscle contraction and the underlying molecular and cellular signatures.Serum β -Catenin Levels Associated with the Ratio of RANKL/OPG in Patients with Postmenopausal Osteoporosis.The enigmas of bone without osteocytes.Serum sclerostin levels in renal cell carcinoma patients with bone metastases The effect on proliferation and differentiation of cementoblast by using sclerostin as inhibitor.Role of Osteocyte-derived Insulin-Like Growth Factor I in Developmental Growth, Modeling, Remodeling, and Regeneration of the Bone.

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Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway

http://www.wikidata.org/entity/Q31032805

description

2011 nî lūn-bûn

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2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Sclerostin stimulates osteocyt ...... y by a RANKL-dependent pathway

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Sclerostin stimulates osteocyt ...... y by a RANKL-dependent pathway

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type

label

Sclerostin stimulates osteocyt ...... y by a RANKL-dependent pathway

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Sclerostin stimulates osteocyt ...... y by a RANKL-dependent pathway

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Sclerostin stimulates osteocyt ...... y by a RANKL-dependent pathway

@ast

Sclerostin stimulates osteocyt ...... y by a RANKL-dependent pathway

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JOURNAL.PONE.0025900

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Sclerostin stimulates osteocyt ...... y by a RANKL-dependent pathway

@en

P2093

Asiri R Wijenayaka

http://www.w3.org/2001/XMLSchema#string

David M Findlay

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Hui Peng Lim

http://www.w3.org/2001/XMLSchema#string

Lynda F Bonewald

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Masakazu Kogawa

http://www.w3.org/2001/XMLSchema#string

P2860

Bone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator function

Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

Wnt modulators in the biotech pipeline

Distinct modes of inhibition by sclerostin on bone morphogenetic protein and Wnt signaling pathways

Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist

Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease

A 52-kb deletion in the SOST-MEOX1 intergenic region on 17q12-q21 is associated with van Buchem disease in the Dutch population

Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling

Matrix-embedded cells control osteoclast formation

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

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e25900

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scholarly article

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10.1371/JOURNAL.PONE.0025900

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10

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6

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Gerald J Atkins

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2011-10-04T00:00:00Z

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51710655

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21991382

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3186800

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