The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure
about
The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA functionLet-7 and miR-200 microRNAs: guardians against pluripotency and cancer progressionThe TRIM-NHL protein LIN-41 controls the onset of developmental plasticity in Caenorhabditis eleganslin-28 controls the succession of cell fate choices via two distinct activitiesThe let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferationThe ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signalingThe RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea.Lin41/Trim71 is essential for mouse development and specifically expressed in postnatal ependymal cells of the brain.Recombinant Adeno-Associated Virus-Mediated microRNA Delivery into the Postnatal Mouse Brain Reveals a Role for miR-134 in Dendritogenesis in VivoExpressing and characterization of mLIN-41 in mouse early embryos and adult muscle tissues.E3 Ubiquitin Ligases Neurobiological Mechanisms: Development to DegenerationThe ubiquitin ligase LIN41/TRIM71 targets p53 to antagonize cell death and differentiation pathways during stem cell differentiation.Exosomes derived from human umbilical cord mesenchymal stem cells protect against cisplatin-induced ovarian granulosa cell stress and apoptosis in vitro.Dicer is required for the transition from early to late progenitor state in the developing mouse retina.Gene expression in teratogenic exposures: a new approach to understanding individual risk.MicroRNAs as the cause of schizophrenia in 22q11.2 deletion carriers, and possible implications for idiopathic disease: a mini-review.The TRIM-NHL protein LIN-41 and the OMA RNA-binding proteins antagonistically control the prophase-to-metaphase transition and growth of Caenorhabditis elegans oocytes.The heterochronic genes lin-28a and lin-28b play an essential and evolutionarily conserved role in early zebrafish development.MicroRNA gene expression signatures in the developing neural tubeLet-7 and miR-125 cooperate to prime progenitors for astrogliogenesis.Co-existence of intact stemness and priming of neural differentiation programs in mES cells lacking Trim71.As the fat flies: The dynamic lipid droplets of Drosophila embryosTrim69 regulates zebrafish brain development by ap-1 pathway.A let-7-to-miR-125 MicroRNA Switch Regulates Neuronal Integrity and Lifespan in Drosophila.miRNAs give worms the time of their lives: small RNAs and temporal control in Caenorhabditis elegansFGF regulates TGF-β signaling and endothelial-to-mesenchymal transition via control of let-7 miRNA expression.LIN-41/TRIM71: emancipation of a miRNA targetSpecification of neural cell fate and regulation of neural stem cell proliferation by microRNAsmicroRNAs: innovative targets for cerebral ischemia and stroke.A balanced chromosomal translocation involving chromosomes 3 and 16 in a patient with Mayer-Rokitansky-Kuster-Hauser syndrome reveals new candidate genes at 3p22.3 and 16p13.3.Deciphering the stem cell machinery as a basis for understanding the molecular mechanism underlying reprogramming.The let-7/LIN-41 pathway regulates reprogramming to human induced pluripotent stem cells by controlling expression of prodifferentiation genes.Born to run: creating the muscle fiber.MicroRNAs in brain development and degeneration.MicroRNAs in acute leukemia: from biological players to clinical contributors.MicroRNAs: a light into the "black box" of neuropediatric diseases?Lin28 and let-7: ancient milestones on the road from pluripotency to neurogenesis.Cell-intrinsic timing in animal development.miRNA expression profiling in a human stem cell-based model as a tool for developmental neurotoxicity testing.
P2860
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P2860
The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
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2008年學術文章
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name
The let-7 microRNA target gene ...... rvival and neural tube closure
@ast
The let-7 microRNA target gene ...... rvival and neural tube closure
@en
The let-7 microRNA target gene ...... rvival and neural tube closure
@nl
type
label
The let-7 microRNA target gene ...... rvival and neural tube closure
@ast
The let-7 microRNA target gene ...... rvival and neural tube closure
@en
The let-7 microRNA target gene ...... rvival and neural tube closure
@nl
prefLabel
The let-7 microRNA target gene ...... rvival and neural tube closure
@ast
The let-7 microRNA target gene ...... rvival and neural tube closure
@en
The let-7 microRNA target gene ...... rvival and neural tube closure
@nl
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P2860
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The let-7 microRNA target gene ...... rvival and neural tube closure
@en
P2093
Betsy R Maller Schulman
Carlos Stahlhut
Casey DelConte
Frank J Slack
Giovanni Stefani
Xianping Liang
P2860
P304
P3181
P356
10.4161/CC.7.24.7397
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P577
2008-12-15T00:00:00Z