lin-28 controls the succession of cell fate choices via two distinct activities
about
Mutations in conserved residues of the C. elegans microRNA Argonaute ALG-1 identify separable functions in ALG-1 miRISC loading and target repressionLin28: primal regulator of growth and metabolism in stem cellsDivergent LIN28-mRNA associations result in translational suppression upon the initiation of differentiation.RACK-1 regulates let-7 microRNA expression and terminal cell differentiation in Caenorhabditis elegans.Pluripotent cells will not dosage compensate.Caenorhabditis elegans period homolog lin-42 regulates the timing of heterochronic miRNA expression.The TRIM-NHL protein LIN-41 and the OMA RNA-binding proteins antagonistically control the prophase-to-metaphase transition and growth of Caenorhabditis elegans oocytes.Lin28 promotes the proliferative capacity of neural progenitor cells in brain development.Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress.Staufen Negatively Modulates MicroRNA Activity in Caenorhabditis elegans.Functional relevance of "seed" and "non-seed" sequences in microRNA-mediated promotion of C. elegans developmental progression.How does Lin28 let-7 control development and disease?Lin-28 promotes symmetric stem cell division and drives adaptive growth in the adult Drosophila intestine.Sex-specific regulation of weight and puberty by the Lin28/let-7 axis.LIN-41/TRIM71: emancipation of a miRNA targetMakorin ortholog LEP-2 regulates LIN-28 stability to promote the juvenile-to-adult transition in Caenorhabditis elegans.miRNAs in endothelial cell signaling: the endomiRNAslin28 proteins promote expression of 17∼92 family miRNAs during amphibian development.LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotencyRewiring of embryonic glucose metabolism via suppression of PFK-1 and aldolase during mouse chorioallantoic branching.LIN28 expression in rat spinal cord after injury.Therapeutic potential of microRNA let-7: tumor suppression or impeding normal stemness.Cell-intrinsic timing in animal development.Lin28 regulates HER2 and promotes malignancy through multiple mechanisms.The effects of lanthanum chloride on proliferation and apoptosis of cervical cancer cells: involvement of let-7a and miR-34a microRNAs.Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models.Stage-Specific Timing of the microRNA Regulation of lin-28 by the Heterochronic Gene lin-14 in Caenorhabditis elegans.Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development.An interplay of miRNA abundance and target site architecture determines miRNA activity and specificity.
P2860
Q27316256-9019B3F9-6862-42EC-8ABC-6EE7FF84FD91Q28288454-66D1C562-E63A-4E36-AAEA-297C052F2D28Q33843071-645E6E81-89F2-4130-91F1-9CFA833D1C03Q33953160-A552B7F6-F1EB-478C-B080-4384949B1375Q34194385-E6D57A10-023D-47F0-B8C7-A0DAB8144AD4Q34442206-3ED5B0EE-1A4D-486C-9B7C-30504B2E9509Q34636236-2DF8871D-B862-4100-9E20-DFF9BE728C97Q35568265-70DE02D4-AC62-44C3-8138-519128A3FED0Q35590108-AEF33AC7-932B-4630-BB8B-D18CEFF92A7BQ35938123-67F4720A-BD80-4C77-B72F-D0145E6C6CCAQ36158589-FEDAD08F-E99D-4A58-A4C0-4F5419F999E2Q36204859-888112C7-52D4-4E1D-9AB5-BDB986862D1EQ36245125-4921E612-ED1F-43A0-B821-C8F611685CDEQ36635293-55BB66BB-D6D1-49E5-9A0B-94BB883B6C77Q36732532-FFF07106-BD4A-421A-B3DC-9D4D8B07253DQ36744063-33ABDEAC-CD22-46F9-8E8B-6A837B0A5587Q36828451-E57FA13B-CB2C-444E-80A3-2091EFE9563CQ37169593-4C501EF2-7D37-4DB0-8834-10D53070DB4BQ37530958-1F7895B8-D052-4385-80EF-2FC270EFE1DFQ37612814-DD3A9B38-D961-45DC-80F0-AC7CA26EF3D1Q37724522-3FCD1F9B-8D55-4CC9-BD5D-9A820AA23FCEQ38210867-D471C30B-9706-45DE-901E-858BEE68D263Q38240043-3965AD1B-DF97-4169-8669-9A4A25BE4CA8Q39328419-0C8AB0CD-5A41-4E55-87C7-C7826AA8ED88Q40698479-4BBAF267-72FF-4C91-B97B-B33F0FFEB782Q42545193-8D645522-0767-40D9-B65E-E9475A3558C9Q48244884-607C5E84-7BBD-4FE0-B9AD-2F62988B1384Q50435299-9E54D0AD-5407-4E27-8F8C-F81FD505980BQ55374415-92F76FD2-E073-43DB-9860-B0370C96AF40
P2860
lin-28 controls the succession of cell fate choices via two distinct activities
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2012 nî lūn-bûn
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2012 թուականին հրատարակուած գիտական յօդուած
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2012 թվականին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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lin-28 controls the succession of cell fate choices via two distinct activities
@ast
lin-28 controls the succession of cell fate choices via two distinct activities
@en
lin-28 controls the succession of cell fate choices via two distinct activities
@nl
type
label
lin-28 controls the succession of cell fate choices via two distinct activities
@ast
lin-28 controls the succession of cell fate choices via two distinct activities
@en
lin-28 controls the succession of cell fate choices via two distinct activities
@nl
prefLabel
lin-28 controls the succession of cell fate choices via two distinct activities
@ast
lin-28 controls the succession of cell fate choices via two distinct activities
@en
lin-28 controls the succession of cell fate choices via two distinct activities
@nl
P2093
P2860
P1433
P1476
lin-28 controls the succession of cell fate choices via two distinct activities
@en
P2093
Bhaskar Vadla
Christian Heine
Eric G Moss
Jennifer Alaimo
Kevin Kemper
P2860
P304
P356
10.1371/JOURNAL.PGEN.1002588
P407
P577
2012-01-01T00:00:00Z