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Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA

Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA

http://www.wikidata.org/entity/Q24629461

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Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA.Identification of domains in apobec-1 complementation factor required for RNA binding and apolipoprotein-B mRNA editing The neurofibromatosis type I messenger RNA undergoes base-modification RNA editing An auxiliary factor containing a 240-kDa protein complex is involved in apolipoprotein B RNA editing C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B mRNA-editing enzyme Identification of GRY-RBP as an apolipoprotein B RNA-binding protein that interacts with both apobec-1 and apobec-1 complementation factor to modulate C to U editing Mutagenesis of apobec-1 complementation factor reveals distinct domains that modulate RNA binding, protein-protein interaction with apobec-1, and complementation of C to U RNA-editing activity Secondary structure for the apolipoprotein B mRNA editing site. Au-binding proteins interact with a stem loop Mutagenesis of apobec-1, the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme, reveals distinct domains that mediate cytosine nucleoside deaminase, RNA binding, and RNA editing activity Phosphorylation is a regulatory mechanism in apolipoprotein B mRNA editing An AU-rich sequence element (UUUN[A/U]U) downstream of the edited C in apolipoprotein B mRNA is a high-affinity binding site for Apobec-1: binding of Apobec-1 to this motif in the 3' untranslated region of c-myc increases mRNA stability.Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor.Apolipoprotein B RNA sequence 3' of the mooring sequence and cellular sources of auxiliary factors determine the location and extent of promiscuous editing.APOBEC-1-mediated RNA editing.Hypermutation of ApoB mRNA by rat APOBEC-1 overexpression mimics APOBEC-3 hypermutation.An RNA-binding protein recognizes a mammalian selenocysteine insertion sequence element required for cotranslational incorporation of selenocysteine.Hyperediting of multiple cytidines of apolipoprotein B mRNA by APOBEC-1 requires auxiliary protein(s) but not a mooring sequence motif.Optimization of apolipoprotein B mRNA editing by APOBEC1 apoenzyme and the role of its auxiliary factor, ACF.A sequence-specific RNA-binding protein complements apobec-1 To edit apolipoprotein B mRNA.Editing of human alpha-galactosidase RNA resulting in a pyrimidine to purine conversion.Partial characterization of the auxiliary factors involved in apolipoprotein B mRNA editing through APOBEC-1 affinity chromatography.Overexpression of APOBEC-1 results in mooring sequence-dependent promiscuous RNA editing.Phylogenetic analysis of the apolipoprotein B mRNA-editing region. Evidence for a secondary structure between the mooring sequence and the 3' efficiency element.Commitment of apolipoprotein B RNA to the splicing pathway regulates cytidine-to-uridine editing-site utilization.Hippocampal Characteristics and Invariant Sequence Elements Distribution of GLRA2 and GLRA3 C-to-U Editing Gene regulation by mRNA editing.Two efficiency elements flanking the editing site of cytidine 6666 in the apolipoprotein B mRNA support mooring-dependent editing.Purification, Redox Sensitivity, and RNA Binding Properties of SECIS-binding Protein 2, a Protein Involved in Selenoprotein Biosynthesis

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P2860

Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA

http://www.wikidata.org/entity/Q24629461

description

1993 nî lūn-bûn

@nan

1993 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1993 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1993年の論文

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1993年論文

@yue

1993年論文

@zh-hant

1993年論文

@zh-hk

1993年論文

@zh-mo

1993年論文

@zh-tw

1993年论文

@wuu

name

Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA

@ast

Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA

@en

Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA

@nl

type

label

Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA

@ast

Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA

@en

Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA

@nl

prefLabel

Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA

@ast

Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA

@en

Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA

@nl

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Molecular and Cellular Biology

P1476

Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA

@en

P2093

D M Driscoll

http://www.w3.org/2001/XMLSchema#string

D Martinez

http://www.w3.org/2001/XMLSchema#string

L M Oleksa

http://www.w3.org/2001/XMLSchema#string

S Lakhe-Reddy

http://www.w3.org/2001/XMLSchema#string

P2860

Three distinct RNA sequence elements are required for efficient apolipoprotein B (apoB) RNA editing in vitro

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

Sequence requirements for apolipoprotein B RNA editing in transfected rat hepatoma cells

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels

Sequence requirements for the editing of apolipoprotein B mRNA

A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine

Complete protein sequence and identification of structural domains of human apolipoprotein B

Molecular cloning of an apolipoprotein B messenger RNA editing protein

Ribonucleic acid isolated by cesium chloride centrifugation

Apolipoprotein B mRNA editing: a new tier for the control of gene expression.

P304

7288-94

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scholarly article

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10.1128/MCB.13.12.7288

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12

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13

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1993-12-01T00:00:00Z

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8246950

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364799

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