Mutagenesis of apobec-1 complementation factor reveals distinct domains that modulate RNA binding, protein-protein interaction with apobec-1, and complementation of C to U RNA-editing activity
about
Identification of domains in apobec-1 complementation factor required for RNA binding and apolipoprotein-B mRNA editingThe apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decayA novel nuclear localization signal in the auxiliary domain of apobec-1 complementation factor regulates nucleocytoplasmic import and shuttlingTargeted deletion of the murine apobec-1 complementation factor (acf) gene results in embryonic lethalityMetabolic regulation of apoB mRNA editing is associated with phosphorylation of APOBEC-1 complementation factorMouse and other rodent models of C to U RNA editingAPOBEC1-mediated editing and attenuation of herpes simplex virus 1 DNA indicate that neurons have an antiviral role during herpes simplex encephalitisInvolvement of a chaperone regulator, Bcl2-associated athanogene-4, in apolipoprotein B mRNA editingC to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47Functions and regulation of the APOBEC family of proteinsApobec-1 complementation factor modulates liver regeneration by post-transcriptional regulation of interleukin-6 mRNA stability.APOBEC-1 complementation factor (ACF) forms RNA-dependent multimers.Genome-wide identification and functional analysis of Apobec-1-mediated C-to-U RNA editing in mouse small intestine and liverNMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor.The challenge of target sequence specificity in C-->U RNA editing.APOBEC-1-mediated RNA editing.C-to-U RNA editing: mechanisms leading to genetic diversity.Functional characterization of APOBEC-1 complementation factor phosphorylation sites.Subcellular localization of the APOBEC3 proteins during mitosis and implications for genomic DNA deamination.The multifaceted roles of RNA binding in APOBEC cytidine deaminase functions.Identification of novel alternative splice variants of APOBEC-1 complementation factor with different capacities to support apolipoprotein B mRNA editing.Flow-cytometric visualization of C>U mRNA editing reveals the dynamics of the process in live cells.Optimization of apolipoprotein B mRNA editing by APOBEC1 apoenzyme and the role of its auxiliary factor, ACF.Two interacting proteins are necessary for the editing of the NdhD-1 site in Arabidopsis plastids.
P2860
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P2860
Mutagenesis of apobec-1 complementation factor reveals distinct domains that modulate RNA binding, protein-protein interaction with apobec-1, and complementation of C to U RNA-editing activity
description
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2001
@ast
im Dezember 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 7 December 2001)
@en
vedecký článok (publikovaný 2001/12/07)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/12/07)
@nl
наукова стаття, опублікована в грудні 2001
@uk
name
Mutagenesis of apobec-1 comple ...... of C to U RNA-editing activity
@ast
Mutagenesis of apobec-1 comple ...... of C to U RNA-editing activity
@en
Mutagenesis of apobec-1 comple ...... of C to U RNA-editing activity
@nl
type
label
Mutagenesis of apobec-1 comple ...... of C to U RNA-editing activity
@ast
Mutagenesis of apobec-1 comple ...... of C to U RNA-editing activity
@en
Mutagenesis of apobec-1 comple ...... of C to U RNA-editing activity
@nl
prefLabel
Mutagenesis of apobec-1 comple ...... of C to U RNA-editing activity
@ast
Mutagenesis of apobec-1 comple ...... of C to U RNA-editing activity
@en
Mutagenesis of apobec-1 comple ...... of C to U RNA-editing activity
@nl
P2093
P2860
P356
P1476
Mutagenesis of apobec-1 comple ...... of C to U RNA-editing activity
@en
P2093
J O Henderson
N O Davidson
P2860
P304
P356
10.1074/JBC.M107654200
P407
P577
2001-12-07T00:00:00Z