Respiratory distress and perinatal lethality in Nedd4-2-deficient mice
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Nedd4-2 and the regulation of epithelial sodium transportUbiquitylation and control of renal Na+ balance and blood pressureThe acute respiratory distress syndrome: from mechanism to translationThe Concise Guide to PHARMACOLOGY 2013/14: ion channelsEndocytic regulation of alkali metal transport proteins in mammals, yeast and plants.Impact of genetic background on neonatal lethality of Gga2 gene-trap mice.Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertensionNedd4-2 (NEDD4L) controls intracellular Na(+)-mediated activity of voltage-gated sodium channels in primary cortical neurons.The short isoform of the ubiquitin ligase NEDD4L is a CREB target gene in hepatocytes.Regulation of ENaC-mediated alveolar fluid clearance by insulin via PI3K/Akt pathway in LPS-induced acute lung injuryEpilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors.Identification of extracellular domain residues required for epithelial Na+ channel activation by acidic pHHECT domain-containing E3 ubiquitin ligase NEDD4L negatively regulates Wnt signaling by targeting dishevelled for proteasomal degradation.Destabilization of Lysophosphatidic Acid Receptor 1 Reduces Cytokine Release and Protects Against Lung Injury.Nedd4-2 haploinsufficiency causes hyperactivity and increased sensitivity to inflammatory stimuliThe Nedd4-2/Ndfip1 axis is a negative regulator of IgE-mediated mast cell activation.TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury.Deletion of Nedd4-2 results in progressive kidney disease in mice.Hypercapnia Impairs ENaC Cell Surface Stability by Promoting Phosphorylation, Polyubiquitination and Endocytosis of β-ENaC in a Human Alveolar Epithelial Cell Line.The phosphorylation of endogenous Nedd4-2 In Na(+)-absorbing human airway epithelial cellsUbiquitination and the Regulation of Membrane Proteins.Feedback modulation of neural network synchrony and seizure susceptibility by Mdm2-p53-Nedd4-2 signaling.Rac1 acts in conjunction with Nedd4 and dishevelled-1 to promote maturation of cell-cell contacts.An isoform of Nedd4-2 is critically involved in the renal adaptation to high salt intake in miceUbiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3).Regulation of Lung Epithelial Sodium Channels by Cytokines and Chemokines.Ubiquitylation and the pathogenesis of hypertension.Restoration of Epithelial Sodium Channel Function by Synthetic Peptides in Pseudohypoaldosteronism Type 1B Mutants.δβγ-ENaC is inhibited by CFTR but stimulated by cAMP in Xenopus laevis oocytes.SPLUNC1 is an allosteric modulator of the epithelial sodium channel.High-Throughput Screening of HECT E3 Ubiquitin Ligases Using UbFluor.A mutation in the β-subunit of ENaC identified in a patient with cystic fibrosis-like symptoms has a gain-of-function effect.NEDD4-2-dependent control of Na+ homeostasis and renal disease.Renal Tubular Ubiquitin-Protein Ligase NEDD4-2 Is Required for Renal Adaptation during Long-Term Potassium Depletion.UbFluor: A Fluorescent Thioester to Monitor HECT E3 Ligase Catalysis.The Ubiquitin Ligase Nedd4L Regulates the Na/K/2Cl Co-transporter NKCC1/SLC12A2 in the Colon.
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P2860
Respiratory distress and perinatal lethality in Nedd4-2-deficient mice
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Respiratory distress and perinatal lethality in Nedd4-2-deficient mice
@ast
Respiratory distress and perinatal lethality in Nedd4-2-deficient mice
@en
Respiratory distress and perinatal lethality in Nedd4-2-deficient mice
@nl
type
label
Respiratory distress and perinatal lethality in Nedd4-2-deficient mice
@ast
Respiratory distress and perinatal lethality in Nedd4-2-deficient mice
@en
Respiratory distress and perinatal lethality in Nedd4-2-deficient mice
@nl
prefLabel
Respiratory distress and perinatal lethality in Nedd4-2-deficient mice
@ast
Respiratory distress and perinatal lethality in Nedd4-2-deficient mice
@en
Respiratory distress and perinatal lethality in Nedd4-2-deficient mice
@nl
P2093
P2860
P50
P3181
P356
P1476
Respiratory distress and perinatal lethality in Nedd4-2-deficient mice
@en
P2093
Anuwat Dinudom
Chris Semsarian
David I Cook
Eleanora Candi
Frank Koentgen
Gerry Melino
Natasha A Boase
Scott L Townley
Tatiana Tsoutsman
P2860
P2888
P3181
P356
10.1038/NCOMMS1284
P407
P577
2011-01-01T00:00:00Z
P5875
P6179
1005999387