Nedd4 controls animal growth by regulating IGF-1 signaling
about
Nedd4-2 and the regulation of epithelial sodium transportMolecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advancesRegulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite developmentNedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and functionUpregulation of the E3 ligase NEDD4-1 by oxidative stress degrades IGF-1 receptor protein in neurodegenerationNedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cellsRespiratory distress and perinatal lethality in Nedd4-2-deficient miceUbiquitin-dependent regulation of phospho-AKT dynamics by the ubiquitin E3 ligase, NEDD4-1, in the insulin-like growth factor-1 responseNedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functionsAbnormal development of the neuromuscular junction in Nedd4-deficient miceRegulation of insulin and type 1 insulin-like growth factor signaling and action by the Grb10/14 and SH2B1/B2 adaptor proteinsNEDD4: a promising target for cancer therapySUMOylation regulates the homologous to E6-AP carboxyl terminus (HECT) ubiquitin ligase Rsp5p.Nedd4 E3 ubiquitin ligase promotes cell proliferation and autophagyPTEN is a protein tyrosine phosphatase for IRS1The Thoc1 encoded ribonucleoprotein is a substrate for the NEDD4-1 E3 ubiquitin protein ligasePhosphorylation of Kif26b promotes its polyubiquitination and subsequent proteasomal degradation during kidney developmentThe ubiquitin ligase Nedd4-1 is required for heart development and is a suppressor of thrombospondin-1E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arraysE3 ubiquitin-protein ligases in rat kidney collecting duct: response to vasopressin stimulation and withdrawalEndocytic regulation of alkali metal transport proteins in mammals, yeast and plants.Regulation of glioma migration and invasion via modification of Rap2a activity by the ubiquitin ligase Nedd4-1.Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc.NEDD4 controls spermatogonial stem cell homeostasis and stress response by regulating messenger ribonucleoprotein complexes.Comparative muscle transcriptome associated with carcass traits of Nellore cattle.The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.Abnormal splicing of NEDD4 in myotonic dystrophy type 2: possible link to statin adverse reactions.Natural polymorphism in BUL2 links cellular amino acid availability with chronological aging and telomere maintenance in yeast.A splice isoform of DNedd4, DNedd4-long, negatively regulates neuromuscular synaptogenesis and viability in Drosophila.Alterations in the developing testis transcriptome following embryonic vinclozolin exposureSomething old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulationThe ubiquitin ligase Nedd4-1 participates in denervation-induced skeletal muscle atrophy in mice.NEDD4-1 regulates migration and invasion of glioma cells through CNrasGEF ubiquitination in vitro.Nedd4 haploinsufficient mice display moderate insulin resistance, enhanced lipolysis, and protection against high-fat diet-induced obesity.Monoallelic loss of the imprinted gene Grb10 promotes tumor formation in irradiated Nf1+/- mice.E3 ubiquitin ligase Cbl-b regulates Pten via Nedd4 in T cells independently of its ubiquitin ligase activityNEDD4 Regulates PAX7 Levels Promoting Activation of the Differentiation Program in Skeletal Muscle Precursors.NEDD4 ubiquitin ligase is a putative oncogene in endometrial cancer that activates IGF-1R/PI3K/Akt signalingThe E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters.
P2860
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P2860
Nedd4 controls animal growth by regulating IGF-1 signaling
description
2008 nî lūn-bûn
@nan
2008 թուականին հրատարակուած գիտական յօդուած
@hyw
2008 թվականին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Nedd4 controls animal growth by regulating IGF-1 signaling
@ast
Nedd4 controls animal growth by regulating IGF-1 signaling
@en
Nedd4 controls animal growth by regulating IGF-1 signaling
@nl
type
label
Nedd4 controls animal growth by regulating IGF-1 signaling
@ast
Nedd4 controls animal growth by regulating IGF-1 signaling
@en
Nedd4 controls animal growth by regulating IGF-1 signaling
@nl
prefLabel
Nedd4 controls animal growth by regulating IGF-1 signaling
@ast
Nedd4 controls animal growth by regulating IGF-1 signaling
@en
Nedd4 controls animal growth by regulating IGF-1 signaling
@nl
P2093
P2860
P50
P1433
P1476
Nedd4 controls animal growth by regulating IGF-1 signaling
@en
P2093
Baoli Yang
Eileen M Sweezer
Hongbo Shan
Nancy L Lill
Natasha Boase
Patricia A Kirby
Peijun P Shi
Trenton Place
Xiao R Cao
P2860
P356
10.1126/SCISIGNAL.1160940
P407
P577
2008-01-01T00:00:00Z