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CAS proteins in normal and pathological cell growth control

CAS proteins in normal and pathological cell growth control

http://www.wikidata.org/entity/Q24630247

about

NEDD9 and BCAR1 negatively regulate E-cadherin membrane localization, and promote E-cadherin degradation Dcas supports cell polarization and cell-cell adhesion complexes in development Cas proteins: dodgy scaffolding in breast cancer EFS shows biallelic methylation in uveal melanoma with poor prognosis as well as tissue-specific methylation The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: new therapeutic targets Protein-intrinsic and signaling network-based sources of resistance to EGFR- and ErbB family-targeted therapies in head and neck cancer Late-Onset Alzheimer's Disease Genes and the Potentially Implicated Pathways Preclinical and clinical studies of the NEDD9 scaffold protein in cancer and other diseases CAS proteins in health and disease: an update A complex RARE is required for the majority of Nedd9 embryonic expression Nedd9 restrains renal cystogenesis in Pkd1-/- mice Order and disorder in large multi-site docking proteins of the Gab family--implications for signalling complex formation and inhibitor design strategies Protein pathway activation mapping reveals molecular networks associated with antiestrogen resistance in breast cancer cell lines Cas and NEDD9 Contribute to Tumor Progression through Dynamic Regulation of the Cytoskeleton.NSP-CAS Protein Complexes: Emerging Signaling Modules in Cancer Expression of NEDD9 in pancreatic ductal adenocarcinoma and its clinical significance A requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 mice Association of the breast cancer antiestrogen resistance protein 1 (BCAR1) and BCAR3 scaffolding proteins in cell signaling and antiestrogen resistance ZNF-mediated resistance to imatinib mesylate in gastrointestinal stromal tumor Embryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family members Aurora kinases in head and neck cancer Early beginnings - the emergence of complex signaling systems and cell-to-cell communication Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2.The role of focal adhesion anchoring domains of CAS in mechanotransduction.Identification of Novel Crk-associated Substrate (p130Cas) Variants with Functionally Distinct Focal Adhesion Kinase Binding Activities Essential roles of Crk and CrkL in fibroblast structure and motility.The SH2 domain protein Shep1 regulates the in vivo signaling function of the scaffolding protein Cas Expression of a phosphorylated substrate domain of p130Cas promotes PyMT-induced c-Src-dependent murine breast cancer progression.SRChing for the substrates of Src.Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation.Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome.p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF.Dysregulation of Blimp1 transcriptional repressor unleashes p130Cas/ErbB2 breast cancer invasion.Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology.p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells.SOX2 enhances the migration and invasion of ovarian cancer cells via Src kinase Carcinoma matrix controls resistance to cisplatin through talin regulation of NF-kB Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease Nephrin regulates lamellipodia formation by assembling a protein complex that includes Ship2, filamin and lamellipodin BCAR1 protein plays important roles in carcinogenesis and predicts poor prognosis in non-small-cell lung cancer

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CAS proteins in normal and pathological cell growth control

http://www.wikidata.org/entity/Q24630247

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

CAS proteins in normal and pathological cell growth control

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CAS proteins in normal and pathological cell growth control

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CAS proteins in normal and pathological cell growth control

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type

label

CAS proteins in normal and pathological cell growth control

@ast

CAS proteins in normal and pathological cell growth control

@en

CAS proteins in normal and pathological cell growth control

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prefLabel

CAS proteins in normal and pathological cell growth control

@ast

CAS proteins in normal and pathological cell growth control

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CAS proteins in normal and pathological cell growth control

@nl

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Cellular and Molecular Life Sciences

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CAS proteins in normal and pathological cell growth control

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Erica A Golemis

http://www.w3.org/2001/XMLSchema#string

Joy L Little

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Nadezhda Tikhmyanova

http://www.w3.org/2001/XMLSchema#string

P2860

Breast cancer oestrogen independence mediated by BCAR1 or BCAR3 genes is transmitted through mechanisms distinct from the oestrogen receptor signalling pathway or the epidermal growth factor receptor signalling pathway

Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

Signal transduction pathways in the mitogenic response to G protein-coupled neuropeptide receptor agonists

Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas

BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells

Integrin signalling: a new Cas(t) of characters enters the stage

Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers

Molecular basis for regulation of Src by the docking protein p130Cas

Sphingosine-1-phosphate induces the association of membrane-type 1 matrix metalloproteinase with p130Cas in endothelial cells

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10.1007/S00018-009-0213-1

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