A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin - Wikidata - wikimedia - TriplyDB

A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin

A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin

http://www.wikidata.org/entity/Q24630256

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How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion Genome Editing Using Mammalian Haploid Cells Structure-based mechanism for Na+/melibiose symport by MelB Hunting Viral Receptors Using Haploid Cells Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death Major facilitator superfamily domain-containing protein 2a (MFSD2A) has roles in body growth, motor function, and lipid metabolism Mfsd2a is critical for the formation and function of the blood-brain barrier Haploid genetic screens identify an essential role for PLP2 in the downregulation of novel plasma membrane targets by viral E3 ubiquitin ligases Functional toxicology: tools to advance the future of toxicity testing.Suppression of conformation-compromised mutants of Salmonella enterica serovar Typhimurium MelB.Haploid genomes illustrate epigenetic constraints and gene dosage effects in mammals.Target identification for small bioactive molecules: finding the needle in the haystack.The major cellular sterol regulatory pathway is required for Andes virus infection Knocking out the door to tunicamycin entry.tRNA modifications regulate translation during cellular stress.Functional genomic screening approaches in mechanistic toxicology and potential future applications of CRISPR-Cas9.Role of Gly117 in the cation/melibiose symport of MelB of Salmonella typhimurium Identification of Genes That Modulate Susceptibility to Formaldehyde and Imatinib by Functional Genomic Screening in Human Haploid KBM7 Cells.Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome.Attachment of Chlamydia trachomatis L2 to host cells requires sulfation.In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse Recombinase-based conditional and reversible gene regulation via XTR alleles Genome-wide barcoded transposon screen for cancer drug sensitivity in haploid mouse embryonic stem cells.A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor.The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity.A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens.Single-cell and multivariate approaches in genetic perturbation screens.High-Throughput Silencing Using the CRISPR-Cas9 System: A Review of the Benefits and Challenges.Reversibility of endothelial dysfunction in diabetes: role of polyphenols.The protein synthesis inhibitor blasticidin s enters mammalian cells via leucine-rich repeat-containing protein 8D.The unfolded protein response genes in human osteoarthritic chondrocytes: PERK emerges as a potential therapeutic target.The anticancer natural product ophiobolin A induces cytotoxicity by covalent modification of phosphatidylethanolamine.DHA supplementation during pregnancy as phospholipids or TAG produces different placental uptake but similar fetal brain accretion in neonatal piglets.HaSAPPy: A tool for candidate identification in pooled forward genetic screens of haploid mammalian cells.Golgi stress-induced transcriptional changes mediated by MAPK signaling and three ETS transcription factors regulate MCL1 splicing.A mouse model reveals that Mfsd2a is critical for unfolded protein response upon exposure to tunicamycin.Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis.Quercetin ameliorates tunicamycin-induced endoplasmic reticulum stress in endothelial cells.Double function at the blood–brain barrier

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A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin

http://www.wikidata.org/entity/Q24630256

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2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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A haploid genetic screen ident ...... in the response to tunicamycin

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A haploid genetic screen ident ...... in the response to tunicamycin

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A haploid genetic screen ident ...... in the response to tunicamycin

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A haploid genetic screen ident ...... in the response to tunicamycin

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A haploid genetic screen ident ...... in the response to tunicamycin

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Proceedings of the National Academy of Sciences of the United States of America

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A haploid genetic screen ident ...... in the response to tunicamycin

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Clary B Clish

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David M Sabatini

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Jan E Carette

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Jan H Reiling

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Malini Varadarajan

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Thijn R Brummelkamp

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P2860

Haploid genetic screens in human cells identify host factors used by pathogens

Major facilitator superfamily

Mfsd2a encodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis

Signal integration in the endoplasmic reticulum unfolded protein response

Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae.

Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

Fatty acid transport protein 1 is required for nonshivering thermogenesis in brown adipose tissue

Roles of N-linked glycans in the endoplasmic reticulum

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

Arg-52 in the melibiose carrier of Escherichia coli is important for cation-coupled sugar transport and participates in an intrahelical salt bridge.

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29

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108

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3141996

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