Haploid genetic screens in human cells identify host factors used by pathogens
about
How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusionChemogenomic approach identified yeast YLR143W as diphthamide synthetaseEbola virus entry requires the cholesterol transporter Niemann-Pick C1A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycinLipolysis-stimulated lipoprotein receptor (LSR) is the host receptor for the binary toxin Clostridium difficile transferase (CDT)Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screensA Journey of Cytolethal Distending Toxins through Cell MembranesMaking Bunyaviruses Talk: Interrogation Tactics to Identify Host Factors Required for InfectionGenome Editing Using Mammalian Haploid CellsApplication of toxicogenomic profiling to evaluate effects of benzene and formaldehyde: from yeast to humanThe diphthamide modification pathway from Saccharomyces cerevisiae--revisitedA metabolic network approach for the identification and prioritization of antimicrobial drug targetsGenome wide functional genetics in haploid cellsSialic acid-dependent cell entry of human enterovirus D68.The adherens junctions control susceptibility to Staphylococcus aureus α-toxinGenome-wide CRISPR screen reveals novel host factors required for Staphylococcus aureus α-hemolysin-mediated toxicity.Subcellular redistribution and sequential recruitment of macromolecular components during SGIV assembly.YBR246W is required for the third step of diphthamide biosynthesisTwo novel WD40 domain-containing proteins, Ere1 and Ere2, function in the retromer-mediated endosomal recycling pathway.Dph7 catalyzes a previously unknown demethylation step in diphthamide biosynthesis.The amidation step of diphthamide biosynthesis in yeast requires DPH6, a gene identified through mining the DPH1-DPH5 interaction networkThe Cytolethal Distending Toxin Contributes to Microbial Virulence and Disease Pathogenesis by Acting As a Tri-Perditious ToxinHunting Viral Receptors Using Haploid CellsRAS Synthetic Lethal Screens Revisited: Still Seeking the Elusive Prize?Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell DeathThe biosynthesis and biological function of diphthamideA dominant-negative approach that prevents diphthamide formation confers resistance to Pseudomonas exotoxin A and diphtheria toxinA genetic screen using the PiggyBac transposon in haploid cells identifies Parp1 as a mediator of olaparib toxicityCCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cellsHaploid genetic screens identify an essential role for PLP2 in the downregulation of novel plasma membrane targets by viral E3 ubiquitin ligasesRNAi screening comes of age: improved techniques and complementary approachesGene-trap mutagenesis identifies mammalian genes contributing to intoxication by Clostridium perfringens ε-toxinGene essentiality and synthetic lethality in haploid human cellsApplication of human haploid cell genetic screening model in identifying the genes required for resistance to environmental toxicants: Chlorpyrifos as a case studyPLA2G16 represents a switch between entry and clearance of PicornaviridaeGenome-scale CRISPR-Cas9 knockout screening in human cellsGenetic screens in human cells using the CRISPR-Cas9 systemTMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I.A CRISPR toolbox to study virus-host interactionsFunctional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells.
P2860
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P2860
Haploid genetic screens in human cells identify host factors used by pathogens
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Haploid genetic screens in human cells identify host factors used by pathogens
@ast
Haploid genetic screens in human cells identify host factors used by pathogens
@en
Haploid genetic screens in human cells identify host factors used by pathogens
@en-gb
Haploid genetic screens in human cells identify host factors used by pathogens
@nl
type
label
Haploid genetic screens in human cells identify host factors used by pathogens
@ast
Haploid genetic screens in human cells identify host factors used by pathogens
@en
Haploid genetic screens in human cells identify host factors used by pathogens
@en-gb
Haploid genetic screens in human cells identify host factors used by pathogens
@nl
prefLabel
Haploid genetic screens in human cells identify host factors used by pathogens
@ast
Haploid genetic screens in human cells identify host factors used by pathogens
@en
Haploid genetic screens in human cells identify host factors used by pathogens
@en-gb
Haploid genetic screens in human cells identify host factors used by pathogens
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Haploid genetic screens in human cells identify host factors used by pathogens
@en
P2093
Alzbeta Godarova
Annie S Park
Carla P Guimaraes
Eric Spooner
Hidde L Ploegh
Irene Wuethrich
Maciej Kotecki
Malini Varadarajan
Thijn R Brummelkamp
P2860
P304
P3181
P356
10.1126/SCIENCE.1178955
P407
P577
2009-11-01T00:00:00Z