Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding
about
Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesisKrüppel-like factor 2 is required for normal mouse cardiac developmentRNA sequencing analysis reveals protective role of kruppel-like factor 3 in colorectal cancer.Heme-bound iron activates placenta growth factor in erythroid cells via erythroid Krüppel-like factorKrüppel-like transcription factors KLF1 and KLF2 have unique and coordinate roles in regulating embryonic erythroid precursor maturation.Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencingNotch1 regulates progenitor cell proliferation and differentiation during mouse yolk sac hematopoiesis.Regulation of delta-aminolevulinic acid dehydratase by krüppel-like factor 1.ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2.The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells.Human gene-centered transcription factor networks for enhancers and disease variants.Krüppel-Like Transcription Factor KLF1 Is Required for Optimal γ- and β-Globin Expression in Human Fetal Erythroblasts.The expression of embryonic globin mRNA in a severely anemic mouse model induced by treatment with nitrogen-containing bisphosphonate.Simvastatin and t-butylhydroquinone suppress KLF1 and BCL11A gene expression and additively increase fetal hemoglobin in primary human erythroid cellsManganese superoxide dismutase depletion in murine hematopoietic stem cells perturbs iron homeostasis, globin switching, and epigenetic control in erythrocyte precursor cells.EKLF/KLF1, a tissue-restricted integrator of transcriptional control, chromatin remodeling, and lineage determination.Krüppel-like factors in mammalian stem cells and development.GATA1 Activity Governed by Configurations of cis-Acting Elements.ε-globin expression is regulated by SUV4-20h1.Regulation of endothelial hemoglobin alpha expression by Kruppel-like factors.The intrinsic genetic and epigenetic regulator factors as therapeutic targets, and the effect on fetal globin gene expression.Mouse Models of Erythropoiesis and Associated Diseases.KLF10gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in β-hemoglobinopathy patients
P2860
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P2860
Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding
description
2011 nî lūn-bûn
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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
Transcription factors KLF1 and ...... hrough direct promoter binding
@ast
Transcription factors KLF1 and ...... hrough direct promoter binding
@en
Transcription factors KLF1 and ...... hrough direct promoter binding
@nl
type
label
Transcription factors KLF1 and ...... hrough direct promoter binding
@ast
Transcription factors KLF1 and ...... hrough direct promoter binding
@en
Transcription factors KLF1 and ...... hrough direct promoter binding
@nl
prefLabel
Transcription factors KLF1 and ...... hrough direct promoter binding
@ast
Transcription factors KLF1 and ...... hrough direct promoter binding
@en
Transcription factors KLF1 and ...... hrough direct promoter binding
@nl
P2093
P2860
P356
P1476
Transcription factors KLF1 and ...... hrough direct promoter binding
@en
P2093
Divya S Vinjamur
Joyce A Lloyd
Karin M L Gaensler
Mohua Basu
Ursula Klingmüller
Yousef N Alhashem
P2860
P304
P356
10.1074/JBC.M111.247536
P407
P577
2011-07-15T00:00:00Z