ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2. - Wikidata - wikimedia - TriplyDB

ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2.

ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2.

http://www.wikidata.org/entity/Q35064898

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Early Loss of Splenic Tfh Cells in SIV-Infected Rhesus Macaques Regulators of Tfh Cell Differentiation ICOS Co-Stimulation: Friend or Foe?Exit Strategies: S1P Signaling and T Cell Migration Production of IgG antibodies to pneumococcal polysaccharides is associated with expansion of ICOS+ circulating memory T follicular-helper cells which is impaired by HIV infection.Human Immunodeficiency Virus Playing Hide-and-Seek: Understanding the TFH Cell Reservoir and Proposing Strategies to Overcome the Follicle Sanctuary Successive annual influenza vaccination induces a recurrent oligoclonotypic memory response in circulating T follicular helper cells.Targeting the Human T-Cell Inducible COStimulator Molecule with a Monoclonal Antibody Prevents Graft-vs-Host Disease and Preserves Graft vs Leukemia in a Xenograft Murine Model The curious origins of angioimmunoblastic T-cell lymphoma BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms.LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6 miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity.IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection.The Costimulatory Molecule ICOS Regulates Host Th1 and Follicular Th Cell Differentiation in Response to Plasmodium chabaudi chabaudi AS Infection.IL-7 signalling represses Bcl-6 and the TFH gene program.B Cells Negatively Regulate the Establishment of CD49b(+)T-bet(+) Resting Memory T Helper Cells in the Bone Marrow Inducible T-cell co-stimulator ligand (ICOSL) blockade leads to selective inhibition of anti-KLH IgG responses in subjects with systemic lupus erythematosus.CD4 memory T cells develop and acquire functional competence by sequential cognate interactions and stepwise gene regulation A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1.The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6 CD4 T Follicular Helper Cells and HIV Infection: Friends or Enemies?T follicular helper cells in the generation of alloantibody and graft rejection.Heterogeneity of Phenotype and Function Reflects the Multistage Development of T Follicular Helper Cells.Insights into the development and regulation of T follicular helper cells.T follicular helper cell programming by cytokine-mediated events.Immune checkpoint proteins: exploring their therapeutic potential to regulate atherosclerosis.Signals that drive T follicular helper cell formation.Characterization of the Microenvironment of Nodular Lymphocyte Predominant Hodgkin Lymphoma.Metabolism in Immune Cell Differentiation and Function.IL-6 promotes CD4+ T-cell and B-cell activation during Plasmodium infection.mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation.ICOS regulates the pool of group 2 innate lymphoid cells under homeostatic and inflammatory conditions in mice.Precocious Interleukin 21 Expression in Naive Mice Identifies a Natural Helper Cell Population in Autoimmune Disease.Regulation of T follicular helper cells by ICOS.ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses.Quantitative Multiplexed Imaging Analysis Reveals a Strong Association between Immunogen-Specific B Cell Responses and Tonsillar Germinal Center Immune Dynamics in Children after Influenza Vaccination.STAT4 and T-bet control follicular helper T cell development in viral infections.Frequency and distribution of CD4+CXCR5+ follicular B helper T cells within involved tissues in IgG4‑related ophthalmic disease.Attenuation of Follicular Helper T Cell-Dependent B Cell Hyperactivity by Abatacept Treatment in Primary Sjögren's Syndrome.Tfr cells lack IL-2Rα but express decoy IL-1R2 and IL-1Ra and suppress the IL-1-dependent activation of Tfh cells.

P2860

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P2860

ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2.

http://www.wikidata.org/entity/Q35064898

description

2015 nî lūn-bûn

@nan

2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

ICOS maintains the T follicula ...... ulating Krüppel-like factor 2.

@ast

ICOS maintains the T follicula ...... ulating Krüppel-like factor 2.

@en

type

label

ICOS maintains the T follicula ...... ulating Krüppel-like factor 2.

@ast

ICOS maintains the T follicula ...... ulating Krüppel-like factor 2.

@en

prefLabel

ICOS maintains the T follicula ...... ulating Krüppel-like factor 2.

@ast

ICOS maintains the T follicula ...... ulating Krüppel-like factor 2.

@en

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Journal of Experimental Medicine

P1476

ICOS maintains the T follicula ...... ulating Krüppel-like factor 2.

@en

P2093

Andreas Radbruch

http://www.w3.org/2001/XMLSchema#string

Claudia Haftmann

http://www.w3.org/2001/XMLSchema#string

Dana Vu Van

http://www.w3.org/2001/XMLSchema#string

Franziska Fuhrmann

http://www.w3.org/2001/XMLSchema#string

Hans W Mages

http://www.w3.org/2001/XMLSchema#string

Jan P Weber

http://www.w3.org/2001/XMLSchema#string

Lea-Jean Gentz

http://www.w3.org/2001/XMLSchema#string

Maysun S Al Baz

http://www.w3.org/2001/XMLSchema#string

Randi K Feist

http://www.w3.org/2001/XMLSchema#string

Richard A Kroczek

http://www.w3.org/2001/XMLSchema#string

P2860

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cells

Roquin differentiates the specialized functions of duplicated T cell costimulatory receptor genes CD28 and ICOS

Follicular helper T cells in immunity and systemic autoimmunity

Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

Molecular programming of B cell memory

FOXO transcription factors throughout T cell biology

Structure and dynamics of a primordial catalytic fold generated by in vitro evolution

P304

217-233

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scholarly article

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10.1084/JEM.20141432

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P433

2

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P478

212

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P50

Mir-Farzin Mashreghi

Andreas Hutloff

Joachim R. Grün

Annette Lahmann

P577

2015-02-02T00:00:00Z

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271703859

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25646266

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4322049

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