Reduced expression of glutamate receptors and phosphorylation of CREB are responsible for in vivo Delta9-THC exposure-impaired hippocampal synaptic plasticity
about
Delta9-tetrahydrocannabinol is a full agonist at CB1 receptors on GABA neuron axon terminals in the hippocampusBrain regional differences in CB1 receptor adaptation and regulation of transcriptionMismatch Negativity and P50 Sensory Gating in Abstinent Former Cannabis Users.Opposite monosynaptic scaling of BLP-vCA1 inputs governs hopefulness- and helplessness-modulated spatial learning and memoryDrugs of abuse and increased risk of psychosis development.Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment.Δ9-THC-caused synaptic and memory impairments are mediated through COX-2 signalingSynaptic and cognitive improvements by inhibition of 2-AG metabolism are through upregulation of microRNA-188-3p in a mouse model of Alzheimer's disease.The cannabinoid receptor 1 associates with NMDA receptors to produce glutamatergic hypofunction: implications in psychosis and schizophrenia.Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity.Ovarian hormones and chronic administration during adolescence modify the discriminative stimulus effects of delta-9-tetrahydrocannabinol (Δ⁹-THC) in adult female rats.Neurodevelopmental role for VGLUT2 in pyramidal neuron plasticity, dendritic refinement, and in spatial learning.Monoacylglycerol lipase is a therapeutic target for Alzheimer's diseaseDissociation of the pharmacological effects of THC by mTOR blockade.Synaptic targets of Δ9-tetrahydrocannabinol in the central nervous system.HINT1 protein cooperates with cannabinoid 1 receptor to negatively regulate glutamate NMDA receptor activity.Cellular and intracellular mechanisms involved in the cognitive impairment of cannabinoids.Effects of drugs of abuse on hippocampal plasticity and hippocampus-dependent learning and memory: contributions to development and maintenance of addiction.Interactions between the Kynurenine and the Endocannabinoid System with Special Emphasis on MigraineEndocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction.Endogenous 2-Arachidonoylglycerol Alleviates Cyclooxygenases-2 Elevation-Mediated Neuronal Injury From SO2 Inhalation via PPARγ Pathway.Cannabinoid receptors couple to NMDA receptors to reduce the production of NO and the mobilization of zinc induced by glutamate.Schizophrenia and depression, two poles of endocannabinoid system deregulation.THC Treatment Alters Glutamate Receptor Gene Expression in Human Stem Cell-Derived Neurons.Chronic activation of CB2 cannabinoid receptors in the hippocampus increases excitatory synaptic transmission.Long-lasting potentiation of hippocampal synaptic transmission by direct cortical input is mediated via endocannabinoids.
P2860
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P2860
Reduced expression of glutamate receptors and phosphorylation of CREB are responsible for in vivo Delta9-THC exposure-impaired hippocampal synaptic plasticity
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Reduced expression of glutamat ...... ippocampal synaptic plasticity
@ast
Reduced expression of glutamat ...... ippocampal synaptic plasticity
@en
Reduced expression of glutamat ...... ippocampal synaptic plasticity
@nl
type
label
Reduced expression of glutamat ...... ippocampal synaptic plasticity
@ast
Reduced expression of glutamat ...... ippocampal synaptic plasticity
@en
Reduced expression of glutamat ...... ippocampal synaptic plasticity
@nl
prefLabel
Reduced expression of glutamat ...... ippocampal synaptic plasticity
@ast
Reduced expression of glutamat ...... ippocampal synaptic plasticity
@en
Reduced expression of glutamat ...... ippocampal synaptic plasticity
@nl
P2093
P2860
P3181
P1476
Reduced expression of glutamat ...... ippocampal synaptic plasticity
@en
P2093
P2860
P304
P3181
P356
10.1111/J.1471-4159.2009.06489.X
P407
P577
2010-02-01T00:00:00Z