TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions - Wikidata - wikimedia - TriplyDB

TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions

TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions

http://www.wikidata.org/entity/Q24644588

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Identification and characterization of a novel mammalian Mg2+ transporter with channel-like properties.The TRPM7 chanzyme is cleaved to release a chromatin-modifying kinase International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7 TRPM7 and its role in neurodegenerative diseases Current understanding of TRPM7 pharmacology and drug development for stroke Permeation, regulation and control of expression of TRP channels by trace metal ions TRPM channels and magnesium in early embryonic development Lpe10p modulates the activity of the Mrs2p-based yeast mitochondrial Mg2+ channel.Insights into the molecular nature of magnesium homeostasis Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex Charge Shielding of PIP2 by Cations Regulates Enzyme Activity of Phospholipase C Differential regulation of transient receptor potential melastatin 6 and 7 cation channels by ANG II in vascular smooth muscle cells from spontaneously hypertensive rats Regulation of a TRPM7-like current in rat brain microglia Hypoxia induces an increase in intracellular magnesium via transient receptor potential melastatin 7 (TRPM7) channels in rat hippocampal neurons in vitro TRP channels TRPM7 Pathophysiologically relevant levels of hydrogen peroxide induce glutamate-independent neurodegeneration that involves activation of transient receptor potential melastatin 7 channels TRPM7 regulates polarized cell movements.TRPM channels modulate epileptic-like convulsions via systemic ion homeostasis TRPM7 and ischemic CNS injury.Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.Development and optimization of a high-throughput bioassay for TRPM7 ion channel inhibitors.Blockade of TRPM7 channel activity and cell death by inhibitors of 5-lipoxygenase.TRPM7 activates m-calpain by stress-dependent stimulation of p38 MAPK and c-Jun N-terminal kinase.Zn2+ activates large conductance Ca2+-activated K+ channel via an intracellular domain.Zinc-induced neurotoxicity mediated by transient receptor potential melastatin 7 channels.Role of TRPM7 in Cancer: Potential as Molecular Biomarker and Therapeutic Target.Inactivation of TRPM7 kinase activity does not impair its channel function in mice.A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders.Cellular functions of transient receptor potential channels.Waixenicin A inhibits cell proliferation through magnesium-dependent block of transient receptor potential melastatin 7 (TRPM7) channels Inhibition of TRPM7 channels reduces degranulation and release of cytokines in rat bone marrow-derived mast cells Are TRP channels involved in sperm development and function?Magnesium and embryonic development.The TRP superfamily of cation channels.Identification of a Mg2+-sensitive ORF in the 5'-leader of TRPM7 magnesium channel mRNA The modulation of TRPM7 currents by nafamostat mesilate depends directly upon extracellular concentrations of divalent cations

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P2860

TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions

http://www.wikidata.org/entity/Q24644588

description

2003 nî lūn-bûn

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2003 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2003 թվականի հունվարին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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name

TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions

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TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions

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TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions

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TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions

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TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions

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TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions

@nl

prefLabel

TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions

@ast

TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions

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TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions

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The Journal of General Physiology

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TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions

@en

P2093

Andrew M Scharenberg

http://www.w3.org/2001/XMLSchema#string

Mahealani K Monteilh-Zoller

http://www.w3.org/2001/XMLSchema#string

Meredith C Hermosura

http://www.w3.org/2001/XMLSchema#string

Monica J S Nadler

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P2860

Functional expression of the human hZIP2 zinc transporter

The human ZIP1 transporter mediates zinc uptake in human K562 erythroleukemia cells

The capsaicin receptor: a heat-activated ion channel in the pain pathway

Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

TRP-PLIK, a bifunctional protein with kinase and ion channel activities

LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

Nramp 2 (DCT1/DMT1) expressed at the plasma membrane transports iron and other divalent cations into a calcein-accessible cytoplasmic pool

A rat kidney-specific calcium transporter in the distal nephron

Calcium signalling.

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49-60

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scholarly article

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3283345

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10.1085/JGP.20028740

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121

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10968294

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12508053

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2217320

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