Waixenicin A inhibits cell proliferation through magnesium-dependent block of transient receptor potential melastatin 7 (TRPM7) channels
about
Calcium influx pathways in breast cancer: opportunities for pharmacological interventionTranscriptome sequencing of tumor subpopulations reveals a spectrum of therapeutic options for squamous cell lung cancerPlasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasionTRPM7Transient receptor potential (TRP) channels: a clinical perspectiveRole of TRPM7 in Cancer: Potential as Molecular Biomarker and Therapeutic Target.Activation of TRPM7 channels by small molecules under physiological conditions.Quantitative imaging of magnesium distribution at single-cell resolution in brain tumors and infiltrating tumor cells with secondary ion mass spectrometry (SIMS)Natural and synthetic modulators of SK (K(ca)2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7Sphingosine and FTY720 are potent inhibitors of the transient receptor potential melastatin 7 (TRPM7) channels.TRPM7 Regulates Axonal Outgrowth and Maturation of Primary Hippocampal Neurons.TRPM7 is regulated by halides through its kinase domainTRPM7 triggers Ca2+ sparks and invadosome formation in neuroblastoma cellsThe TRPM6 kinase domain determines the Mg·ATP sensitivity of TRPM7/M6 heteromeric ion channels.The Pathophysiologic Roles of TRPM7 Channel.Magnesium and its transporters in cancer: a novel paradigm in tumour development.A survey of marine natural compounds and their derivatives with anti-cancer activity reported in 2011.New insights into pharmacological tools to TR(i)P cancer up.Proton-sensitive cation channels and ion exchangers in ischemic brain injury: new therapeutic targets for stroke?Oncogenic role and therapeutic target of transient receptor potential melastatin 7 channel in malignancy.Cellular and Developmental Biology of TRPM7 Channel-Kinase: Implicated Roles in Cancer.Natural products from marine organisms with neuroprotective activity in the experimental models of Alzheimer's disease, Parkinson's disease and ischemic brain stroke: their molecular targets and action mechanisms.Natural and Synthetic Modulators of the TRPM7 Channel.Functional characterization of TRPM7 in nasopharyngeal carcinoma and its knockdown effects on tumorigenesis.Transient Receptor Potential Channels in Microglia: Roles in Physiology and Disease.Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion.TRPM7 maintains progenitor-like features of neuroblastoma cells: implications for metastasis formation.N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation.TRPM7 channels regulate glioma stem cell through STAT3 and Notch signaling pathways.The role of waixenicin A as transient receptor potential melastatin 7 blocker.TRPM7 is a molecular substrate of ATP-evoked P2X7-like currents in tumor cells.The coiled-coil domain of zebrafish TRPM7 regulates Mg·nucleotide sensitivity.Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in miceLeucettamols, bifunctionalized marine sphingoids, act as modulators of TRPA1 and TRPM8 channelsTanshinone IIA alleviates lipopolysaccharide-induced acute lung injury by downregulating TRPM7 and pro-inflammatory factors.New insights into Ca2+ channel function in health and disease.Swelling-induced chloride current in glioblastoma proliferation, migration, and invasion.Role of TRPM7 in cerebral ischaemia and hypoxia.The TRPM7 channel kinase regulates store-operated calcium entry.Involvement of transient receptor potential melastatin type 7 channels on Poncirus fructus-induced depolarizations of pacemaking activity in interstitial cells of Cajal from murine small intestine.
P2860
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P2860
Waixenicin A inhibits cell proliferation through magnesium-dependent block of transient receptor potential melastatin 7 (TRPM7) channels
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Waixenicin A inhibits cell pro ...... melastatin 7 (TRPM7) channels
@ast
Waixenicin A inhibits cell pro ...... melastatin 7 (TRPM7) channels
@en
Waixenicin A inhibits cell pro ...... eceptor potential melastatin 7
@nl
type
label
Waixenicin A inhibits cell pro ...... melastatin 7 (TRPM7) channels
@ast
Waixenicin A inhibits cell pro ...... melastatin 7 (TRPM7) channels
@en
Waixenicin A inhibits cell pro ...... eceptor potential melastatin 7
@nl
prefLabel
Waixenicin A inhibits cell pro ...... melastatin 7 (TRPM7) channels
@ast
Waixenicin A inhibits cell pro ...... melastatin 7 (TRPM7) channels
@en
Waixenicin A inhibits cell pro ...... eceptor potential melastatin 7
@nl
P2093
P2860
P356
P1476
Waixenicin A inhibits cell pro ...... melastatin 7 (TRPM7) channels
@en
P2093
Andrea Fleig
F David Horgen
Guangmin Yao
Peter Pörzgen
Reinhold Penner
Susanna Zierler
W Cedric Kuo
Zheng Zhang
P2860
P304
39328-39335
P356
10.1074/JBC.M111.264341
P407
P577
2011-09-16T00:00:00Z