Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas - Wikidata - wikimedia - TriplyDB

Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas

Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas

http://www.wikidata.org/entity/Q24645081

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Variant base excision repair proteins: contributors to genomic instability In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C Base excision repair Colorectal carcinomas in MUTYH-associated polyposis display histopathological similarities to microsatellite unstable carcinomas A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer.MUTYH Associated Polyposis (MAP).Physical and functional interactions between Escherichia coli MutY glycosylase and mismatch repair protein MutS Mammalian MutY homolog (MYH or MUTYH) protects cells from oxidative DNA damage.Functional characterization of human MutY homolog (hMYH) missense mutation (R231L) that is linked with hMYH-associated polyposis.MUTYH gene variants and breast cancer in a Dutch case–control study.The role of MYH and microsatellite instability in the development of sporadic colorectal cancer.Adenoma development in familial adenomatous polyposis and MUTYH-associated polyposis: somatic landscape and driver genes.Pathological features of colorectal carcinomas in MYH-associated polyposis.MUTYH-associated colorectal cancer and adenomatous polyposis.Gastrointestinal polyposis syndromes for the general gastroenterologist.Therapeutic targeting of oncogenic K-Ras by a covalent catalytic site inhibitor MUTYH-associated polyposis (MAP), the syndrome implicating base excision repair in inherited predisposition to colorectal tumors.Oxidative DNA damage drives carcinogenesis in MUTYH-associated-polyposis by specific mutations of mitochondrial and MAPK genes.Mutational signature analysis identifies MUTYH deficiency in colorectal cancers and adrenocortical carcinomas.A role for Myh1 in DNA repair after treatment with strand-breaking and crosslinking chemotherapeutic agents.Mitochondrial variants in MT-CO2 and D-loop instability are involved in MUTYH-associated polyposis.Is prophylactic colectomy indicated in patients with MYH-associated polyposis?Unresectable metastatic colorectal cancer patient cured with cetuximab-based chemotherapy: a case report with new molecular insights

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P2860

Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas

http://www.wikidata.org/entity/Q24645081

description

2004 nî lūn-bûn

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2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2004 թվականի ապրիլին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas

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Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas

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Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas

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Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas

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Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas

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Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas

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Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas

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Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas

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Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas

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British Journal of Cancer

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Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas

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G T Williams

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J M Best

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J P Cheadle

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J R Sampson

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S Jones

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S Lambert

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P2860

A genetic model for colorectal tumorigenesis

Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH

Exposing the MYtH about base excision repair and human inherited disease

Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C-->T:A mutations

Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH

ras oncogenes in human cancer: a review

Pathology of colorectal adenomas: a colonoscopic survey.

Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors.

Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression.

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