Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors.
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MUTYH DNA glycosylase: the rationale for removing undamaged bases from the DNAFamilial adenomatous polyposisEvaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predispositionAn oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stressRole of PCNA-dependent stimulation of 3'-phosphodiesterase and 3'-5' exonuclease activities of human Ape2 in repair of oxidative DNA damageMolecular origins of cancer: Molecular basis of colorectal cancerUnbalanced replication as a major source of genetic instability in cancer cellsInherited colorectal cancer syndromesIncreased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomasAzathioprine and UVA light generate mutagenic oxidative DNA damageFunctional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposisA functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA8-oxoguanine incorporation into DNA repeats in vitro and mismatch recognition by MutSalpha.Gut Microbiota Imbalance and Base Excision Repair Dynamics in Colon CancerClinical Genetic Testing in GastroenterologyMolecular approach to genetic and epigenetic pathogenesis of early-onset colorectal cancerRepair of oxidative DNA damage and cancer: recent progress in DNA base excision repairCellular levels of 8-oxoguanine in either DNA or the nucleotide pool play pivotal roles in carcinogenesis and survival of cancer cellsDNA glycosylases: in DNA repair and beyondMUTYH the base excision repair gene family member associated with colorectal cancer polyposisBase excision repair and cancerStructure of a trapped endonuclease III-DNA covalent intermediateAtomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylaseA Structural Hinge in Eukaryotic MutY Homologues Mediates Catalytic Activity and Rad9–Rad1–Hus1 Checkpoint Complex InteractionsBinary complex crystal structure of DNA polymerase reveals multiple conformations of the templating 8-oxoguanine lesionOpportunities for immunotherapy in microsatellite instable colorectal cancerThe genetic heterogeneity of colorectal cancer predisposition - guidelines for gene discoveryGermline susceptibility to colorectal cancer due to base-excision repair gene defects.A germline homozygous mutation in the base-excision repair gene NTHL1 causes adenomatous polyposis and colorectal cancerOxidative damage is increased in human liver tissue adjacent to hepatocellular carcinomaNTHL1 defines novel cancer syndromeColorectal cancer and genetic alterations in the Wnt pathwayDNA polymerase ε and δ exonuclease domain mutations in endometrial cancerAssociation between biallelic and monoallelic germline MYH gene mutations and colorectal cancer riskDNA damage response genes and the development of cancer metastasisSearch for new loci and low-frequency variants influencing glioma risk by exome-array analysisAdenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancerBase-excision repair of oxidative DNA damageSusceptibility to human cancer: From the perspective of a pathologist.Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer.
P2860
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P2860
Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Inherited variants of MYH asso ...... utations in colorectal tumors.
@en
Inherited variants of MYH asso ...... utations in colorectal tumors.
@nl
type
label
Inherited variants of MYH asso ...... utations in colorectal tumors.
@en
Inherited variants of MYH asso ...... utations in colorectal tumors.
@nl
prefLabel
Inherited variants of MYH asso ...... utations in colorectal tumors.
@en
Inherited variants of MYH asso ...... utations in colorectal tumors.
@nl
P2093
P356
P1433
P1476
Inherited variants of MYH asso ...... utations in colorectal tumors.
@en
P2093
Alison L Livingston
D Rhodri Davies
Geraint T Williams
Jeremy P Cheadle
Julian R Sampson
Julie Maynard
Nada Al-Tassan
Nick Fleming
Nikolas H Chmiel
Sheila S David
P2888
P304
P356
10.1038/NG828
P407
P577
2002-01-30T00:00:00Z
P5875
P6179
1001834006