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Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localizationFifteen-year quest for microphthalmia-associated transcription factor target genesNetworks and pathways in pigmentation, health, and disease.PAX6 regulates melanogenesis in the retinal pigmented epithelium through feed-forward regulatory interactions with MITF.Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein.Silencing of GPNMB by siRNA inhibits the formation of melanosomes in melanocytes in a MITF-independent fashionComparison of melanoblast expression patterns identifies distinct classes of genesInhibition of Phosphatase Activity Follows Decline in Sulfatase Activity and Leads to Transcriptional Effects through Sustained Phosphorylation of Transcription Factor MITF.Genetic dissection of the Gpnmb network in the eyeMutation in Osteoactivin Promotes Receptor Activator of NFκB Ligand (RANKL)-mediated Osteoclast Differentiation and Survival but Inhibits Osteoclast FunctionIn Silico Analysis of Gene Expression Network Components Underlying Pigmentation Phenotypes in the Python Identified Evolutionarily Conserved Clusters of Transcription Factor Binding SitesCandidate genes contributing to the aggressive phenotype of mantle cell lymphoma.Integration of ChIP-seq and machine learning reveals enhancers and a predictive regulatory sequence vocabulary in melanocytes.The PKD domain distinguishes the trafficking and amyloidogenic properties of the pigment cell protein PMEL and its homologue GPNMB.Glycoprotein non-metastatic b (GPNMB): A metastatic mediator and emerging therapeutic target in cancer.Estrogen maintains myometrial tumors in a lymphangioleiomyomatosis modelOcular Albinism Type 1 Regulates Melanogenesis in Mouse Melanocytes.Emerging therapeutic targets in breast cancer bone metastasis.Glycoprotein NMB: an Emerging Role in Neurodegenerative Disease.Minireview: Lymphangioleiomyomatosis (LAM): The "Other" Steroid-Sensitive Cancer.mitfa is required at multiple stages of melanocyte differentiation but not to establish the melanocyte stem cell.Endothelin-1 enhances the melanogenesis via MITF-GPNMB pathway.Interleukin-22 participates in the inflammatory process of vitiligo.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Gpnmb is a melanoblast-expressed, MITF-dependent gene
@ast
Gpnmb is a melanoblast-expressed, MITF-dependent gene
@en
Gpnmb is a melanoblast-expressed, MITF-dependent gene
@nl
type
label
Gpnmb is a melanoblast-expressed, MITF-dependent gene
@ast
Gpnmb is a melanoblast-expressed, MITF-dependent gene
@en
Gpnmb is a melanoblast-expressed, MITF-dependent gene
@nl
prefLabel
Gpnmb is a melanoblast-expressed, MITF-dependent gene
@ast
Gpnmb is a melanoblast-expressed, MITF-dependent gene
@en
Gpnmb is a melanoblast-expressed, MITF-dependent gene
@nl
P2093
P2860
P50
P3181
P1476
Gpnmb is a melanoblast-expressed, MITF-dependent gene
@en
P2093
Andrew S McCallion
Chenwei Wang
Duncan Reid
Gabriel Renaud
Ivana Matera
Megana K Prasad
Seneca L Bessling
Tyra G Wolfsberg
Yidong Chen
P2860
P304
P3181
P356
10.1111/J.1755-148X.2008.00518.X
P407
P577
2009-02-01T00:00:00Z