Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin - Wikidata - wikimedia - TriplyDB

Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin

Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin

http://www.wikidata.org/entity/Q24646870

about

Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity Co-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasion Selective ROCK2 inhibition in focal cerebral ischemia Rho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapy Novel Insights into the Roles of Rho Kinase in Cancer The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease B cells in chronic graft-versus-host disease Regulation of ROCK activity in cancer RNA-sequencing analysis of HepG2 cells treated with atorvastatin Cutting Edge: Selective Oral ROCK2 Inhibitor Reduces Clinical Scores in Patients with Psoriasis Vulgaris and Normalizes Skin Pathology via Concurrent Regulation of IL-17 and IL-10 Selective inhibition of brain endothelial Rho-kinase-2 provides optimal protection of an in vitro blood-brain barrier from tissue-type plasminogen activator and plasmin.Rho kinase proteins display aberrant upregulation in vascular tumors and contribute to vascular tumor growth.Rho-associated coiled-coil containing kinases (ROCK): structure, regulation, and functions.Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism.Rho-kinase in development and heart failure: insights from genetic models Rho kinase as a therapeutic target in cardiovascular disease.Small molecule inhibition of cytoskeletal dynamics in melanoma tumors results in altered transcriptional expression patterns of key genes involved in tumor initiation and progression.Regulation of glucose transport by ROCK1 differs from that of ROCK2 and is controlled by actin polymerization Therapeutic management of intestinal fibrosis induced by radiation therapy: from molecular profiling to new intervention strategies et vice et versa ROCK2 primes the endothelium for vascular hyperpermeability responses by raising baseline junctional tension ROCK1 & 2 perform overlapping and unique roles in angiogenesis and angiosarcoma tumor progression Rho kinases in cardiovascular physiology and pathophysiology: the effect of fasudil.Rho-kinase inhibition: a novel therapeutic target for the treatment of cardiovascular diseases.Long-term diabetic complications may be ameliorated by targeting Rho kinase.New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis.Targeting Rho GTPase signaling for cancer therapy.Fasudil and its analogs: a new powerful weapon in the long war against central nervous system disorders?Actin dynamics in the regulation of endothelial barrier functions and neutrophil recruitment during endotoxemia and sepsis.RhoE/ROCK2 regulates chemoresistance through NF-κB/IL-6/ STAT3 signaling in hepatocellular carcinoma.ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings.Isoform-specific targeting of ROCK proteins in immune cells.Rho kinase-2 activation in human endothelial cells drives lysophosphatidic acid-mediated expression of cell adhesion molecules via NF-kappaB p65.Rho GTPases as therapeutic targets in cancer (Review).Transcriptome Profiling in Systems Vascular Medicine Anti-adipogenic effects of KD025 (SLx-2119), a ROCK2-specific inhibitor, in 3T3-L1 cells.Rho-kinase inhibitors do not expand hematoma volume in acute experimental intracerebral hemorrhage.Role of age, Rho-kinase 2 expression, and G protein-mediated signaling in the myogenic response in mouse small mesenteric arteries

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P2860

Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin

http://www.wikidata.org/entity/Q24646870

description

2008 nî lūn-bûn

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2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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Comparative gene expression pr ...... of Rho kinase or atorvastatin

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MBC.0B013E32830B2891

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Blood Coagulation and Fibrinolysis

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Alessandra Bartolozzi

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David S Loose

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Elsa Paradise

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James L Ellis

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Junru Wang

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Louis M Fink

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Martin Hauer-Jensen

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Paul Sweetnam

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Qiang Fu

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P2860

Gene ontology: tool for the unification of biology

Rho GTPases: biochemistry and biology

HMG CoA reductase inhibitors affect the fibrinolytic system of human vascular cells in vitro: a comparative study using different statins

Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins)

Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells

Clinical pharmacokinetics of atorvastatin.

Inhibition of Rho kinase modulates radiation induced fibrogenic phenotype in intestinal smooth muscle cells through alteration of the cytoskeleton and connective tissue growth factor expression

The Rho-ROCK system as a new therapeutic target for preventing interstitial fibrosis.

Simvastatin ameliorates radiation enteropathy development after localized, fractionated irradiation by a protein C-independent mechanism.

Rho kinase, a promising drug target for neurological disorders.

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709-718

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7

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Marie-Catherine Vozenin

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18832915

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2713681

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