c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130
about
Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligasesLysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome.Advantages of Extracellular Ubiquitin in Modulation of Immune ResponsesF-box protein FBXL2 targets cyclin D2 for ubiquitination and degradation to inhibit leukemic cell proliferationThe proinflammatory role of HECTD2 in innate immunity and experimental lung injuryE3 ligase subunit Fbxo15 and PINK1 kinase regulate cardiolipin synthase 1 stability and mitochondrial function in pneumoniaTargeting F box protein Fbxo3 to control cytokine-driven inflammationRING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunityUbiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4F-box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrestA cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesisUbiquitination and degradation of the thrombopoietin receptor c-Mpl.Inducible STAT3 NH2 terminal mono-ubiquitination promotes BRD4 complex formation to regulate apoptosisErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.Stressor-dependent Alterations in Glycoprotein 130: Implications for Glial Cell Reactivity, Cytokine Signaling and Ganglion Cell Health in GlaucomaThe adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6.Ubiquitination regulates the internalization, endolysosomal sorting, and signaling of the erythropoietin receptorCigarette smoke exposure reveals a novel role for the MEK/ERK1/2 MAPK pathway in regulation of CFTRF-box protein Fbxl18 mediates polyubiquitylation and proteasomal degradation of the pro-apoptotic SCF subunit Fbxl7A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation.Ligand-induced EpoR internalization is mediated by JAK2 and p85 and is impaired by mutations responsible for primary familial and congenital polycythemiaATG9A loss confers resistance to trastuzumab via c-Cbl mediated Her2 degradation.Interleukin-6: A Constitutive Modulator of Glycoprotein 130, Neuroinflammatory and Cell Survival Signaling in Retina.Receptor tyrosine kinase ubiquitylation involves the dynamic regulation of Cbl-Spry2 by intersectin 1 and the Shp2 tyrosine phosphatase.Pathway-based network modeling finds hidden genes in shRNA screen for regulators of acute lymphoblastic leukemia.Unbiased identification of substrates for the Epac1-inducible E3 ubiquitin ligase component SOCS-3.The SOCS box-adapting proteins for ubiquitination and proteasomal degradation.gp130: a promising drug target for cancer therapy.The Roles of Lysosomes in Inflammation and Autoimmune Diseases.An aptamer intrinsically comprising 5-fluoro-2'-deoxyuridine for targeted chemotherapy.Cell regulation by phosphotyrosine-targeted ubiquitin ligases.CBL linker region and RING finger mutations lead to enhanced granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling via elevated levels of JAK2 and LYN.Modulation of phototropic responsiveness in Arabidopsis through ubiquitination of phototropin 1 by the CUL3-Ring E3 ubiquitin ligase CRL3(NPH3).Contribution of lysine 11-linked ubiquitination to MIR2-mediated major histocompatibility complex class I internalizationJanus Kinase 2 Inhibitor AG490 Inhibits the STAT3 Signaling Pathway by Suppressing Protein Translation of gp130.CBL family E3 ubiquitin ligases control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies.Tetraspanin CD9 stabilizes gp130 by preventing its ubiquitin-dependent lysosomal degradation to promote STAT3 activation in glioma stem cells.PTPN11 binds CBL
P2860
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P2860
c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130
@ast
c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130
@en
c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130
@nl
type
label
c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130
@ast
c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130
@en
c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130
@nl
prefLabel
c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130
@ast
c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130
@en
c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130
@nl
P2093
P2860
P3181
P356
P1476
c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130
@en
P2093
Kazuo Sugamura
Keiji Tanaka
Masaaki Murakami
Nobuyuki Tanaka
Toshio Hirano
Yasushi Saeki
Yoshinori Tanaka
P2860
P304
P3181
P356
10.1128/MCB.01784-07
P407
P50
P577
2008-06-02T00:00:00Z