Unbiased identification of substrates for the Epac1-inducible E3 ubiquitin ligase component SOCS-3. - Wikidata - wikimedia - TriplyDB

Unbiased identification of substrates for the Epac1-inducible E3 ubiquitin ligase component SOCS-3.

Unbiased identification of substrates for the Epac1-inducible E3 ubiquitin ligase component SOCS-3.

http://www.wikidata.org/entity/Q37977181

about

SOCS3: An essential physiological inhibitor of signaling by interleukin-6 and G-CSF family cytokines Cyclic AMP sensor EPAC proteins and energy homeostasis.Identification of a Novel, Small Molecule Partial Agonist for the Cyclic AMP Sensor, EPAC1.Flavanoids induce expression of the suppressor of cytokine signalling 3 (SOCS3) gene and suppress IL-6-activated signal transducer and activator of transcription 3 (STAT3) activation in vascular endothelial cells.cAMP signaling increases histone deacetylase 8 expression via the Epac2-Rap1A-Akt pathway in H1299 lung cancer cells.Pharmacodynamic assessment of apremilast for the treatment of moderate-to-severe plaque psoriasis.The Potential of a Novel Class of EPAC-Selective Agonists to Combat Cardiovascular Inflammation.Regulation of JAK/STAT signalling by SOCS in the myocardium.

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Unbiased identification of substrates for the Epac1-inducible E3 ubiquitin ligase component SOCS-3.

http://www.wikidata.org/entity/Q37977181

description

article científic

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article scientifique

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articol științific

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articolo scientifico

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artigo científico

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artigo científico

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artigo científico

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artikel ilmiah

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artikull shkencor

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artículo científico

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name

Unbiased identification of sub ...... uitin ligase component SOCS-3.

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Unbiased identification of sub ...... uitin ligase component SOCS-3.

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type

label

Unbiased identification of sub ...... uitin ligase component SOCS-3.

@en

Unbiased identification of sub ...... uitin ligase component SOCS-3.

@nl

prefLabel

Unbiased identification of sub ...... uitin ligase component SOCS-3.

@en

Unbiased identification of sub ...... uitin ligase component SOCS-3.

@nl

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Biochemical Society Transactions

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Unbiased identification of sub ...... quitin ligase component SOCS-3

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Timothy M Palmer

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P2860

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

Immunity, Inflammation, and Cancer

Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain

PIAS proteins: pleiotropic interactors associated with SUMO

PIAS proteins as regulators of small ubiquitin-related modifier (SUMO) modifications and transcription

Protein tyrosine phosphatases: from genes, to function, to disease

Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells.

A proteomic screen for nucleolar SUMO targets shows SUMOylation modulates the function of Nop5/Nop58.

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215-218

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scholarly article

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10.1042/BST20110629

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1

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40

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Jamie J L Williams

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2012-02-01T00:00:00Z

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22260693

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