NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation
about
The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR-IL-1R by controlling degradation of regnase-1COP9 signalosome controls the Carma1-Bcl10-Malt1 complex upon T-cell stimulationDephosphorylation of Carma1 by PP2A negatively regulates T-cell activationLys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activationPKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitinationThe paracaspase MALT1: biological function and potential for therapeutic inhibitionStructural Basis for Recognition of Diubiquitins by NEMOCrystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase regionRegulation of inflammatory and antiviral signaling by A20.Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell LymphomaThe protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association.Auto-ubiquitination-induced degradation of MALT1-API2 prevents BCL10 destabilization in t(11;18)(q21;q21)-positive MALT lymphoma.NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein.B-cell CLL/lymphoma 10 (BCL10) is required for NF-kappaB production by both canonical and noncanonical pathways and for NF-kappaB-inducing kinase (NIK) phosphorylation.Signaling to NF-kappaB: regulation by ubiquitination.The CBM signalosome: potential therapeutic target for aggressive lymphoma?CARMA1-mediated NF-kappaB and JNK activation in lymphocytes.BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response.Antigen receptor signaling to NF-kappaB via CARMA1, BCL10, and MALT1.Oncogenic CARD11 mutations induce hyperactive signaling by disrupting autoinhibition by the PKC-responsive inhibitory domainMALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes.ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress.Negative regulation of NF-κB signaling in T lymphocytes by the ubiquitin-specific protease USP34Protein ubiquitination in lymphoid malignancies.Monoubiquitination and activity of the paracaspase MALT1 requires glutamate 549 in the dimerization interfaceMALT1-ubiquitination triggers non-genomic NF-κB/IKK signaling upon platelet activationNF-κB signaling pathways regulated by CARMA family of scaffold proteins.T cell receptor-dependent activation of mTOR signaling in T cells is mediated by Carma1 and MALT1, but not Bcl10.MALT1 Protease Activity Is Required for Innate and Adaptive Immune Responses.Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation.Regulation of NF-κB by the CARD proteinsSelective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB.Intramolecular Interactions and Regulation of Cofactor Binding by the Four Repressive Elements in the Caspase Recruitment Domain-containing Protein 11 (CARD11) Inhibitory Domain.A new look at T cell receptor signaling to nuclear factor-κBRegulation of T cell function by the ubiquitin-specific protease USP9X via modulating the Carma1-Bcl10-Malt1 complexCbl- and Nedd4-family ubiquitin ligases: balancing tolerance and immunityThe zinc finger domain of IKKγ (NEMO) protein in health and diseaseUbiquitin in NF-kappaB signaling.Malt1 and cIAP2-Malt1 as effectors of NF-kappaB activation: kissing cousins or distant relatives?Regulation of JNK and p38 MAPK in the immune system: signal integration, propagation and termination.
P2860
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P2860
NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
NEMO recognition of ubiquitina ...... -mediated NF-kappaB activation
@ast
NEMO recognition of ubiquitina ...... -mediated NF-kappaB activation
@en
NEMO recognition of ubiquitina ...... -mediated NF-kappaB activation
@nl
type
label
NEMO recognition of ubiquitina ...... -mediated NF-kappaB activation
@ast
NEMO recognition of ubiquitina ...... -mediated NF-kappaB activation
@en
NEMO recognition of ubiquitina ...... -mediated NF-kappaB activation
@nl
prefLabel
NEMO recognition of ubiquitina ...... -mediated NF-kappaB activation
@ast
NEMO recognition of ubiquitina ...... -mediated NF-kappaB activation
@en
NEMO recognition of ubiquitina ...... -mediated NF-kappaB activation
@nl
P2860
P356
P1476
NEMO recognition of ubiquitina ...... -mediated NF-kappaB activation
@en
P2093
Chuan-Jin Wu
Jonathan D Ashwell
P2860
P304
P356
10.1073/PNAS.0712313105
P407
P577
2008-02-26T00:00:00Z