The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment - Wikidata - wikimedia - TriplyDB

The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment

The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment

http://www.wikidata.org/entity/Q24653914

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Proteomic detection of cancer in asbestosis patients using SELDI-TOF discovered serum protein biomarkers CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity FORMIN a link between kinetochores and microtubule ends Divergent microtubule assembly rates after short- versus long-term loss of end-modulating kinesins.S. pombe kinesins-8 promote both nucleation and catastrophe of microtubules Role of the Number of Microtubules in Chromosome Segregation during Cell Division A non-motor microtubule binding site is essential for the high processivity and mitotic function of kinesin-8 Kif18A NuSAP governs chromosome oscillation by facilitating the Kid-generated polar ejection force Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores.Insight into the molecular mechanism of the multitasking kinesin-8 motor Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe.The kinesin-8 Kip3 scales anaphase spindle length by suppression of midzone microtubule polymerization.Chromosome congression by Kinesin-5 motor-mediated disassembly of longer kinetochore microtubules.Microtubule-sliding activity of a kinesin-8 promotes spindle assembly and spindle-length control.Regulation of Microtubule Growth and Catastrophe: Unifying Theory and Experiment Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases Germinal Cell Aplasia in Kif18a Mutant Male Mice Due to Impaired Chromosome Congression and Dysregulated BubR1 and CENP-E The tetrameric kinesin Kif25 suppresses pre-mitotic centrosome separation to establish proper spindle orientation.Kinesin-8 from fission yeast: a heterodimeric, plus-end-directed motor that can couple microtubule depolymerization to cargo movement Force- and kinesin-8-dependent effects in the spatial regulation of fission yeast microtubule dynamics Ncd motor binding and transport in the spindle.The distribution of polar ejection forces determines the amplitude of chromosome directional instability.The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion.Mechanisms of chromosome behaviour during mitosis Molecular control of kinetochore-microtubule dynamics and chromosome oscillations Coupling between microtubule sliding, plus-end growth and spindle length revealed by kinesin-8 depletion Temporal changes in Hec1 phosphorylation control kinetochore-microtubule attachment stability during mitosis."Artificial mitotic spindle" generated by dielectrophoresis and protein micropatterning supports bidirectional transport of kinesin-coated beads Kif18B interacts with EB1 and controls astral microtubule length during mitosis.A tethering mechanism controls the processivity and kinetochore-microtubule plus-end enrichment of the kinesin-8 Kif18A.The coupling between sister kinetochore directional instability and oscillations in centromere stretch in metaphase PtK1 cells.Molecular crowding creates traffic jams of kinesin motors on microtubules Human chromokinesins promote chromosome congression and spindle microtubule dynamics during mitosis Accurate phosphoregulation of kinetochore-microtubule affinity requires unconstrained molecular interactions.Spatial control of microtubule length and lifetime by opposing stabilizing and destabilizing functions of Kinesin-8 Kinesin-13 regulates the quantity and quality of tubulin inside cilia.Sumoylation of Kif18A plays a role in regulating mitotic progression Probing microtubule polymerisation state at single kinetochores during metaphase chromosome motion Spatial regulation of astral microtubule dynamics by Kif18B in PtK cells.Kinesin-8 effects on mitotic microtubule dynamics contribute to spindle function in fission yeast.

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The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment

http://www.wikidata.org/entity/Q24653914

description

2008 nî lūn-bûn

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2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2008 թվականի փետրվարին հրատարակված գիտական հոդված

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2008年の論文

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The kinesin-8 motor Kif18A sup ...... l mitotic chromosome alignment

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The kinesin-8 motor Kif18A sup ...... l mitotic chromosome alignment

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The kinesin-8 motor Kif18A sup ...... l mitotic chromosome alignment

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The kinesin-8 motor Kif18A sup ...... l mitotic chromosome alignment

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The kinesin-8 motor Kif18A sup ...... l mitotic chromosome alignment

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The kinesin-8 motor Kif18A sup ...... l mitotic chromosome alignment

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The kinesin-8 motor Kif18A sup ...... l mitotic chromosome alignment

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The kinesin-8 motor Kif18A sup ...... l mitotic chromosome alignment

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Developmental Cell

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The kinesin-8 motor Kif18A sup ...... l mitotic chromosome alignment

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George von Dassow

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Jason Stumpff

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Michael Wagenbach

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P2860

The human kinesin Kif18A is a motile microtubule depolymerase essential for chromosome congression

Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference

Mitotic centromere-associated kinesin is important for anaphase chromosome segregation

Motile kinetochores and polar ejection forces dictate chromosome position on the vertebrate mitotic spindle

Directional instability of kinetochore motility during chromosome congression and segregation in mitotic newt lung cells: a push-pull mechanism

MCAK associates with the tips of polymerizing microtubules

The chromokinesin Kid is necessary for chromosome arm orientation and oscillation, but not congression, on mitotic spindles

Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle.

Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner.

Timing and checkpoints in the regulation of mitotic progression

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