The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion. - Wikidata - wikimedia - TriplyDB

The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion.

The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion.

http://www.wikidata.org/entity/Q30490445

about

Kinetochore-microtubule interactions: steps towards bi-orientation The kinetochore interaction network (KIN) of ascomycetes KNL1: bringing order to the kinetochore Review series: The functions and consequences of force at kinetochores Reconstituting the kinetochore–microtubule interface: what, why, and how From equator to pole: splitting chromosomes in mitosis and meiosis FORMIN a link between kinetochores and microtubule ends A comprehensive model to predict mitotic division in budding yeasts.Centromere protein F includes two sites that couple efficiently to depolymerizing microtubules Ska3 Ensures Timely Mitotic Progression by Interacting Directly With Microtubules and Ska1 Microtubule Binding Domain.Kinetochore biorientation in Saccharomyces cerevisiae requires a tightly folded conformation of the Ndc80 complex.The Ndc80 kinetochore complex forms oligomeric arrays along microtubules The kinetochore-bound Ska1 complex tracks depolymerizing microtubules and binds to curved protofilaments.CENP-T provides a structural platform for outer kinetochore assembly Structural basis for microtubule recognition by the human kinetochore Ska complex Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint.CENP-T proteins are conserved centromere receptors of the Ndc80 complex.The Dam1 complex confers microtubule plus end-tracking activity to the Ndc80 kinetochore complex.Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B.The unconventional kinetoplastid kinetochore: from discovery toward functional understanding Aurora B regulates formin mDia3 in achieving metaphase chromosome alignment Mechanism of Ska Recruitment by Ndc80 Complexes to Kinetochores.Multimodal microtubule binding by the Ndc80 kinetochore complex.Looping in on Ndc80 - how does a protein loop at the kinetochore control chromosome segregation?The Ndc80 complex: integrating the kinetochore's many movements.The Ndc80 complex uses a tripartite attachment point to couple microtubule depolymerization to chromosome movement.Direct physical study of kinetochore-microtubule interactions by reconstitution and interrogation with an optical force clamp.Mechanisms of chromosome behaviour during mitosis Catalysis of the microtubule on-rate is the major parameter regulating the depolymerase activity of MCAK.Tubulin depolymerization may be an ancient biological motor.The NDC80 complex proteins Nuf2 and Hec1 make distinct contributions to kinetochore-microtubule attachment in mitosis Tension directly stabilizes reconstituted kinetochore-microtubule attachments.Cortical dynein controls microtubule dynamics to generate pulling forces that position microtubule asters The Ndc80 kinetochore complex directly modulates microtubule dynamics.Long tethers provide high-force coupling of the Dam1 ring to shortening microtubules Dynamic bonds and polar ejection force distribution explain kinetochore oscillations in PtK1 cells.Deformations within moving kinetochores reveal different sites of active and passive force generation.Accurate phosphoregulation of kinetochore-microtubule affinity requires unconstrained molecular interactions.Kinetochores require oligomerization of Dam1 complex to maintain microtubule attachments against tension and promote biorientation.Actin-microtubule coordination at growing microtubule ends

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P2860

The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion.

http://www.wikidata.org/entity/Q30490445

description

2009 nî lūn-bûn

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2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

@zh-tw

2009年论文

@wuu

name

The Ndc80 kinetochore complex ...... ule tips via biased diffusion.

@ast

The Ndc80 kinetochore complex ...... ule tips via biased diffusion.

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type

label

The Ndc80 kinetochore complex ...... ule tips via biased diffusion.

@ast

The Ndc80 kinetochore complex ...... ule tips via biased diffusion.

@en

prefLabel

The Ndc80 kinetochore complex ...... ule tips via biased diffusion.

@ast

The Ndc80 kinetochore complex ...... ule tips via biased diffusion.

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J.CELL.2008.12.045

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P1476

The Ndc80 kinetochore complex ...... ule tips via biased diffusion.

@en

P2093

Andrew D Franck

http://www.w3.org/2001/XMLSchema#string

Andrew F Powers

http://www.w3.org/2001/XMLSchema#string

Beth Gracyzk

http://www.w3.org/2001/XMLSchema#string

Charles L Asbury

http://www.w3.org/2001/XMLSchema#string

Daniel R Gestaut

http://www.w3.org/2001/XMLSchema#string

Jeremy Cooper

http://www.w3.org/2001/XMLSchema#string

Ronnie R Wei

http://www.w3.org/2001/XMLSchema#string

P2860

Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss

The conserved KMN network constitutes the core microtubule-binding site of the kinetochore

Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites.

Kinetochore dynein is required for chromosome motion and congression independent of the spindle checkpoint

The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment

hNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cells

Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex.

Chromosomes can congress to the metaphase plate before biorientation.

The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment

Mps1 phosphorylation of Dam1 couples kinetochores to microtubule plus ends at metaphase.

P304

865-875

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scholarly article

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10.1016/J.CELL.2008.12.045

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5

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136

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Trisha N. Davis

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2009-03-01T00:00:00Z

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24184909

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19269365

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2749323

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