Kalirin-7 is required for synaptic structure and function
about
The Guanine nucleotide exchange factor kalirin-7 is a novel synphilin-1 interacting protein and modifies synphilin-1 aggregate transport and formationMechanisms of synapse and dendrite maintenance and their disruption in psychiatric and neurodegenerative disordersKalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypesDendritic Spines in Depression: What We Learned from Animal ModelsAbnormal kalirin signaling in neuropsychiatric disorders.Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and diseaseFunction and regulation of the Rho guanine nucleotide exchange factor TrioConstitutive knockout of kalirin-7 leads to increased rates of cocaine self-administration.The extracellular signal-regulated kinase 3 (mitogen-activated protein kinase 6 [MAPK6])-MAPK-activated protein kinase 5 signaling complex regulates septin function and dendrite morphologyKalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and functionKalrn plays key roles within and outside of the nervous systemA role for Kalirin-7 in nociceptive sensitization via activity-dependent modulation of spinal synapsesElimination of Kalrn expression in POMC cells reduces anxiety-like behavior and contextual fear learning.In vivo and in vitro analyses of amygdalar function reveal a role for copperPam heterozygous mice reveal essential role for Cu in amygdalar behavioral and synaptic functionThe RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons.Developmental vulnerability of synapses and circuits associated with neuropsychiatric disorders.Haploinsufficiency in peptidylglycine alpha-amidating monooxygenase leads to altered synaptic transmission in the amygdala and impaired emotional responses.Trio is a key guanine nucleotide exchange factor coordinating regulation of the migration and morphogenesis of granule cells in the developing cerebellum.Hippocampal phenotypes in kalirin-deficient mice.Kalirin12 interacts with dynamin.Kalirin loss results in cortical morphological alterationsUsing Kalirin conditional knockout mice to distinguish its role in dopamine receptor mediated behaviorsKalrn promoter usage and isoform expression respond to chronic cocaine exposureGenetic Variant of Kalirin Gene Is Associated with Ischemic Stroke in a Chinese Han Population.Behavioral and morphological responses to cocaine require kalirin7.Kalirin-7, an important component of excitatory synapses, is regulated by estradiol in hippocampal neuronsKalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticityCofilin-1: a modulator of anxiety in mice.Identification of kalirin-7 as a potential post-synaptic density signaling hubControl of synapse development and plasticity by Rho GTPase regulatory proteins.microRNA-Seq reveals cocaine-regulated expression of striatal microRNAs.The RhoGEF trio functions in sculpting class specific dendrite morphogenesis in Drosophila sensory neuronsAn N-terminal Amphipathic Helix Binds Phosphoinositides and Enhances Kalirin Sec14 Domain-mediated Membrane Interactions.Abnormalities of the Duo/Ras-related C3 botulinum toxin substrate 1/p21-activated kinase 1 pathway drive myosin light chain phosphorylation in frontal cortex in schizophrenia.Recruitment of sphingosine kinase to presynaptic terminals by a conserved muscarinic signaling pathway promotes neurotransmitter releaseGlobal Approaches to the Role of miRNAs in Drug-Induced Changes in Gene Expression.A role for kalirin in the response of rat medium spiny neurons to cocaine.A role for Kalirin-7 in corticostriatal synaptic dysfunction in Huntington's diseaseAnalysis of kalirin-7 knockout mice reveals different effects in female mice.
P2860
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P2860
Kalirin-7 is required for synaptic structure and function
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Kalirin-7 is required for synaptic structure and function
@ast
Kalirin-7 is required for synaptic structure and function
@en
Kalirin-7 is required for synaptic structure and function
@nl
type
label
Kalirin-7 is required for synaptic structure and function
@ast
Kalirin-7 is required for synaptic structure and function
@en
Kalirin-7 is required for synaptic structure and function
@nl
prefLabel
Kalirin-7 is required for synaptic structure and function
@ast
Kalirin-7 is required for synaptic structure and function
@en
Kalirin-7 is required for synaptic structure and function
@nl
P2093
P2860
P3181
P1476
Kalirin-7 is required for synaptic structure and function
@en
P2093
Betty A Eipper
Eric D Gaier
Eun-Ji Kim
Richard E Mains
Xin-Ming Ma
Yanping Wang
P2860
P304
P3181
P356
10.1523/JNEUROSCI.4269-08.2008
P407
P577
2008-11-19T00:00:00Z