A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice
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Alterations of GABAergic signaling in autism spectrum disordersAutistic phenotypes and genetic testing: state-of-the-art for the clinical geneticistAdvances in autism genetics: on the threshold of a new neurobiologyNeuroligins and neurexins link synaptic function to cognitive diseaseAutism and brain developmentStructural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesionReduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum exportFRAXE-associated mental retardation protein (FMR2) is an RNA-binding protein with high affinity for G-quartet RNA forming structureStructural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions.Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments.Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor functionShank3 mutant mice display autistic-like behaviours and striatal dysfunctionAbnormal behavior in a chromosome-engineered mouse model for human 15q11-13 duplication seen in autismMonoamine oxidase A and A/B knockout mice display autistic-like features.Autism-associated neuroligin-3 mutations commonly disrupt tonic endocannabinoid signalingAutismNeurexins and neuroligins: recent insights from invertebratesThe structure of neurexin 1α reveals features promoting a role as synaptic organizerBehavioral and cerebellar transmission deficits in mice lacking the autism-linked gene islet brain-2Multiple rare variants in the etiology of autism spectrum disordersKalirin-7 is required for synaptic structure and functionPathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor traffickingAutism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors.Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutationNeuroligins/LRRTMs prevent activity- and Ca2+/calmodulin-dependent synapse elimination in cultured neuronsNeurexins physically and functionally interact with GABA(A) receptorsSynaptic cell adhesionAn autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampusAutism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic functionRIM1alpha and interacting proteins involved in presynaptic plasticity mediate prepulse inhibition and additional behaviors linked to schizophreniaIncreased anxiety-like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior.Common circuit defect of excitatory-inhibitory balance in mouse models of autism.LRRTM2 functions as a neurexin ligand in promoting excitatory synapse formationThe Intracellular Loop of the Glycine Receptor: It's not all about the SizeNeuropathological Mechanisms of Seizures in Autism Spectrum DisorderMouse Genetic Models of Human Brain DisordersFrom molecules to neural morphology: understanding neuroinflammation in autism spectrum conditionPrefrontal Cortex and Social Cognition in Mouse and Man
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P2860
A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
A neuroligin-3 mutation implic ...... synaptic transmission in mice
@ast
A neuroligin-3 mutation implic ...... synaptic transmission in mice
@en
A neuroligin-3 mutation implic ...... synaptic transmission in mice
@nl
type
label
A neuroligin-3 mutation implic ...... synaptic transmission in mice
@ast
A neuroligin-3 mutation implic ...... synaptic transmission in mice
@en
A neuroligin-3 mutation implic ...... synaptic transmission in mice
@nl
prefLabel
A neuroligin-3 mutation implic ...... synaptic transmission in mice
@ast
A neuroligin-3 mutation implic ...... synaptic transmission in mice
@en
A neuroligin-3 mutation implic ...... synaptic transmission in mice
@nl
P2093
P2860
P921
P3181
P356
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A neuroligin-3 mutation implic ...... synaptic transmission in mice
@en
P2093
Jacqueline Blundell
Katsuhiko Tabuchi
Mark R Etherton
Robert E Hammer
Xinran Liu
P2860
P3181
P356
10.1126/SCIENCE.1146221
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P577
2007-10-05T00:00:00Z