The origins of femtomolar protein-ligand binding: hydrogen-bond cooperativity and desolvation energetics in the biotin-(strept)avidin binding site
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Beyond picomolar affinities: quantitative aspects of noncovalent and covalent binding of drugs to proteinsA Distal Point Mutation in the Streptavidin−Biotin Complex Preserves Structure but Diminishes Binding Affinity: Experimental Evidence of Electronic Polarization Effects?How the biotin–streptavidin interaction was made even stronger: investigation via crystallography and a chimaeric tetramerEvolved streptavidin mutants reveal key role of loop residue in high-affinity bindingBinding Interactions of Keratin-Based Hair Fiber Extract to Gold, Keratin, and BMP-2Communication: Physical origins of ionization potential shifts in mixed carboxylic acids and water complexes.Cucurbit[7]uril⋅guest pair with an attomolar dissociation constant.Construction of chimeric dual-chain avidin by tandem fusion of the related avidins.HBonanza: a computer algorithm for molecular-dynamics-trajectory hydrogen-bond analysisFlexibility of a biotinylated ligand in artificial metalloenzymes based on streptavidin--an insight from molecular dynamics simulations with classical and ab initio force fields.Solid-phase bioconjugation of heterobifunctional adaptors for versatile assembly of bispecific targeting ligands.Discovery of an entropically-driven small molecule streptavidin binder from nucleic acid-encoded libraries.Influence of "glow discharge plasma" as an external stimulus on the self-assembly, morphology and binding affinity of gold nanoparticle-streptavidin conjugates.Site-selective ionization of ethanol dimer under the tunable synchrotron VUV radiation and its subsequent fragmentation.The unusual and dynamic character of PX-DNA.Biophysical limits of protein-ligand binding.The origin of the cooperativity in the streptavidin-biotin system: A computational investigation through molecular dynamics simulations.Directed evolution of streptavidin variants using in vitro compartmentalization.Dynamics of the streptavidin-biotin complex in solution and in its crystal lattice: distinct behavior revealed by molecular simulations.A medicinal chemist's guide to molecular interactionsSynthetic mimics of biotin/(strept)avidin.Strong Short-Range Cooperativity in Hydrogen-Bond Chains.Triazole biotin: a tight-binding biotinidase-resistant conjugate.Rationalizing tight ligand binding through cooperative interaction networks.Collisional unfolding of multiprotein complexes reveals cooperative stabilization upon ligand binding.A Streptavidin Binding Site Mutation Yields an Unexpected Result: An Ionized Asp128 Residue Is Not Essential for Strong Biotin Binding.Organic bioelectronics probing conformational changes in surface confined proteins.Natural bond orbital analysis in the ONETEP code: applications to large protein systems.The F130L mutation in streptavidin reduces its binding affinity to biotin through electronic polarization effect.Time-dependent density functional theory study on hydrogen-bonded intramolecular charge-transfer excited state of 4-dimethylamino-benzonitrile in methanol.Effects of Structure and Environment on the Spectroscopic Properties of (3-Amino-Substituted-Thieno[2,3-b] Pyridine-2-yl)Pyridine/Quinolin-2-yl)(Phenyl)Methanones: Experimental and Theoretical Study.A novel method for the labelling of peptides and proteins through a bioorthogonal Staudinger reaction by using 2-cyanoethyl phosphoramidites.
P2860
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P2860
The origins of femtomolar protein-ligand binding: hydrogen-bond cooperativity and desolvation energetics in the biotin-(strept)avidin binding site
description
2007 nî lūn-bûn
@nan
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The origins of femtomolar prot ...... in-(strept)avidin binding site
@ast
The origins of femtomolar prot ...... in-(strept)avidin binding site
@en
The origins of femtomolar prot ...... in-(strept)avidin binding site
@nl
type
label
The origins of femtomolar prot ...... in-(strept)avidin binding site
@ast
The origins of femtomolar prot ...... in-(strept)avidin binding site
@en
The origins of femtomolar prot ...... in-(strept)avidin binding site
@nl
prefLabel
The origins of femtomolar prot ...... in-(strept)avidin binding site
@ast
The origins of femtomolar prot ...... in-(strept)avidin binding site
@en
The origins of femtomolar prot ...... in-(strept)avidin binding site
@nl
P2860
P3181
P356
P1476
The origins of femtomolar prot ...... in-(strept)avidin binding site
@en
P2093
Jason DeChancie
P2860
P304
P3181
P356
10.1021/JA066950N
P407
P50
P577
2007-05-02T00:00:00Z