Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein - Wikidata - wikimedia - TriplyDB

Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein

Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein

http://www.wikidata.org/entity/Q24657293

about

Cullin-RING ubiquitin ligases: global regulation and activation cycles Tracheal development and the von Hippel-Lindau tumor suppressor homolog in Drosophila The Caenorhabditis elegans cell-cycle regulator ZYG-11 defines a conserved family of CUL-2 complex components A yeast two-hybrid system reconstituting substrate recognition of the von Hippel-Lindau tumor suppressor protein Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase.An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells.Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery.Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex Binding and regulation of HIF-1alpha by a subunit of the proteasome complex, PSMA7 FANCC, FANCE, and FANCD2 form a ternary complex essential to the integrity of the Fanconi anemia DNA damage response pathway Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein Loss of BRMS1 promotes a mesenchymal phenotype through NF-κB-dependent regulation of Twist1.Novel Cul3 binding proteins function to remodel E3 ligase complexes.The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation Regulation of HIF-1alpha stability through S-nitrosylation.Do VHL and HIF-1 mirror p53 and Mdm-2? Degradation-transactivation loops of oncoproteins and tumor suppressors.Diversity in genetic in vivo methods for protein-protein interaction studies: from the yeast two-hybrid system to the mammalian split-luciferase system.Diverse effects of mutations in exon II of the von Hippel-Lindau (VHL) tumor suppressor gene on the interaction of pVHL with the cytosolic chaperonin and pVHL-dependent ubiquitin ligase activity.Proven in vitro evolution of protease cathepsin E-inhibitors and -activators at pH 4.5 using a paired peptide method.Clockless yeast and the gears of the clock: how do they mesh?The von Hippel-Lindau tumor suppressor protein: roles in cancer and oxygen sensing.HIF hydroxylation and the mammalian oxygen-sensing pathway Insights into Cullin-RING E3 ubiquitin ligase recruitment: structure of the VHL-EloBC-Cul2 complex Oxygen sensing in cancer.Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family.The ubiquitin conjugating enzyme, UbcM2, engages in novel interactions with components of cullin-3 based E3 ligases.Elongin BC complex prevents degradation of von Hippel-Lindau tumor suppressor gene products.Simulation of the mutation F76del on the von Hippel-Lindau tumor suppressor protein: mechanism of the disease and implications for drug development.The Hsp70 and TRiC/CCT chaperone systems cooperate in vivo to assemble the von Hippel-Lindau tumor suppressor complex.Regulation of the transcriptional activation of the androgen receptor by the UXT-binding protein VHL.Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization.Screening and Identification of the Host Proteins Interacting with Toxoplasma gondii Rhoptry Protein ROP16.Hypoxia inducible factor (HIF) in the tumor microenvironment: friend or foe?Management Strategies and Outcomes for VHL-related Craniospinal Hemangioblastomas.Implications of Von Hippel-Lindau Syndrome and Renal Cell Carcinoma.

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P2860

Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein

http://www.wikidata.org/entity/Q24657293

description

1999 nî lūn-bûn

@nan

1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի օգոստոսին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

Studying interactions of four ...... plex SKP1/cullin/F-box protein

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Studying interactions of four ...... plex SKP1/cullin/F-box protein

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Studying interactions of four ...... plex SKP1/cullin/F-box protein

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type

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Studying interactions of four ...... plex SKP1/cullin/F-box protein

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Studying interactions of four ...... plex SKP1/cullin/F-box protein

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Studying interactions of four ...... plex SKP1/cullin/F-box protein

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Studying interactions of four ...... plex SKP1/cullin/F-box protein

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Studying interactions of four ...... plex SKP1/cullin/F-box protein

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Studying interactions of four ...... plex SKP1/cullin/F-box protein

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P1433

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PNAS.96.17.9533

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Studying interactions of four ...... plex SKP1/cullin/F-box protein

@en

P2093

A Pause

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B Peterson

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G Schaffar

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R D Klausner

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P2860

cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

Inhibition of transcription elongation by the VHL tumor suppressor protein

Elongin (SIII): a multisubunit regulator of elongation by RNA polymerase II

Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C

Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2

Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins.

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.

P304

9533-8

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scholarly article

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10.1073/PNAS.96.17.9533

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17

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P478

96

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1999-08-17T00:00:00Z

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P5875

12849576

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P698

10449727

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P932

22243

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