Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway - Wikidata - wikimedia - TriplyDB

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

http://www.wikidata.org/entity/Q24672316

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Cloning and expression analysis of two distinct HIF-alpha isoforms--gcHIF-1alpha and gcHIF-4alpha--from the hypoxia-tolerant grass carp, Ctenopharyngodon idellus Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1 Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1 FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity Differential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factors Ubiquitin-specific protease 19 (USP19) regulates hypoxia-inducible factor 1α (HIF-1α) during hypoxia Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia IOP1, a novel hydrogenase-like protein that modulates hypoxia-inducible factor-1alpha activity The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1 alpha by a von Hippel-Lindau protein-independent mechanism The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity The phosphorylation status of PAS-B distinguishes HIF-1alpha from HIF-2alpha in NBS1 repression Histone deacetylase inhibitors repress the transactivation potential of hypoxia-inducible factors independently of direct acetylation of HIF-alpha Direct regulation of TWIST by HIF-1alpha promotes metastasis Correlation between the expression of divalent metal transporter 1 and the content of hypoxia-inducible factor-1 in hypoxic HepG2 cells Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF).Two sequence motifs from HIF-1alpha bind to the DNA-binding site of p53.Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.Suppression of hypoxia-inducible factor 1alpha (HIF-1alpha) transcriptional activity by the HIF prolyl hydroxylase EGLN1 Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein HECT and RING finger families of E3 ubiquitin ligases at a glance Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha Ethanol-induced expression of ET-1 and ET-BR in liver sinusoidal endothelial cells and human endothelial cells involves hypoxia-inducible factor-1alpha and microrNA-199 The human side of hypoxia-inducible factor Identification of an alternative mechanism of degradation of the hypoxia-inducible factor-1alpha Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1alpha transcriptional activity Conjugation of the ubiquitin-like protein NEDD8 to cullin-2 is linked to von Hippel-Lindau tumor suppressor function Vanadate-induced expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor through phosphatidylinositol 3-kinase/Akt pathway and reactive oxygen species Conserved transcription factor binding sites of cancer markers derived from primary lung adenocarcinoma microarrays Influence of hypoxia and neoangiogenesis on the growth of pancreatic cancer Hypoxia and oxidative stress in breast cancer. Hypoxia signalling pathways Upregulated hypoxia inducible factor-1alpha and -2alpha pathway in rheumatoid arthritis and osteoarthritis The polypyrimidine tract-binding protein stimulates HIF-1alpha IRES-mediated translation during hypoxia Hypoxia-inducible factor-1alpha polymorphisms and TSC1/2 mutations are complementary in head and neck cancers Role of hypoxia and vascular endothelial growth factors in lymphangiogenesis

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P2860

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

http://www.wikidata.org/entity/Q24672316

description

1998 nî lūn-bûn

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1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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1998 թվականի հուլիսին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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Regulation of hypoxia-inducibl ...... e ubiquitin-proteasome pathway

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Regulation of hypoxia-inducibl ...... e ubiquitin-proteasome pathway

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Regulation of hypoxia-inducibl ...... e ubiquitin-proteasome pathway

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Regulation of hypoxia-inducibl ...... e ubiquitin-proteasome pathway

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Regulation of hypoxia-inducibl ...... e ubiquitin-proteasome pathway

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Regulation of hypoxia-inducibl ...... e ubiquitin-proteasome pathway

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Regulation of hypoxia-inducibl ...... e ubiquitin-proteasome pathway

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Regulation of hypoxia-inducibl ...... e ubiquitin-proteasome pathway

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Regulation of hypoxia-inducibl ...... e ubiquitin-proteasome pathway

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Proceedings of the National Academy of Sciences of the United States of America

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Regulation of hypoxia-inducibl ...... e ubiquitin-proteasome pathway

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H F Bunn

http://www.w3.org/2001/XMLSchema#string

J Gu

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L E Huang

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M Schau

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P2860

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

Structure and functions of the 20S and 26S proteasomes

Protein-protein interaction via PAS domains: role of the PAS domain in positive and negative regulation of the bHLH/PAS dioxin receptor-Arnt transcription factor complex

Identification of functional domains of the aryl hydrocarbon receptor nuclear translocator protein (ARNT)

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

Activation of hypoxia-inducible factor 1alpha: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor

Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension

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7987-92

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10.1073/PNAS.95.14.7987

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14

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95

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13631912

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9653127

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ubiquitin-proteasome system

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20916

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