Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation
about
Role for the regulator of G-protein signaling homology domain of G protein-coupled receptor kinases 5 and 6 in beta 2-adrenergic receptor and rhodopsin phosphorylationMolecular basis for activation of G protein-coupled receptor kinasesProtein and Signaling Networks in Vertebrate Photoreceptor CellsStructure of Human G Protein-Coupled Receptor Kinase 2 in Complex with the Kinase Inhibitor BalanolActivation of G Protein-Coupled Receptor Kinase 1 Involves Interactions between Its N-Terminal Region and Its Kinase DomainMolecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 InhibitorsA Highly Conserved Cysteine of Neuronal Calcium-sensing Proteins Controls Cooperative Binding of Ca2+ to RecoverinStructural and Functional Analysis of G Protein-Coupled Receptor Kinase Inhibition by Paroxetine and a Rationally Designed AnalogStructure of a monomeric variant of rhodopsin kinase at 2.5 Å resolutionMolecular Mechanism for Inhibition of G Protein-Coupled Receptor Kinase 2 by a Selective RNA AptamerMolecular Features of Product Release for the PKA Catalytic CycleStructural approaches to understanding retinal proteins needed for visionAtomic Structure of GRK5 Reveals Distinct Structural Features Novel for G Protein-coupled Receptor KinasesChemistry and biology of the initial steps in vision: the Friedenwald lecture.A functional kinase homology domain is essential for the activity of photoreceptor guanylate cyclase 1Role of helix 8 of the thyrotropin-releasing hormone receptor in phosphorylation by G protein-coupled receptor kinase.Comparative genomics uncovers novel structural and functional features of the heterotrimeric GTPase signaling system.The regulator of G protein signaling (RGS) domain of G protein-coupled receptor kinase 5 (GRK5) regulates plasma membrane localization and function.Mapping the putative G protein-coupled receptor (GPCR) docking site on GPCR kinase 2: insights from intact cell phosphorylation and recruitment assays.Importance of regions outside the cytoplasmic tail of G-protein-coupled receptors for phosphorylation and dephosphorylation.Regulation of mammalian cone phototransduction by recoverin and rhodopsin kinase.Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 bindingRecognition in the face of diversity: interactions of heterotrimeric G proteins and G protein-coupled receptor (GPCR) kinases with activated GPCRsBiochemical and Cellular Specificity of Peptide Inhibitors of G Protein-Coupled Receptor Kinases.Expression, purification, and analysis of G-protein-coupled receptor kinases.Identification and structure-function analysis of subfamily selective G protein-coupled receptor kinase inhibitorsMembrane orientation and binding determinants of G protein-coupled receptor kinase 5 as assessed by combined vibrational spectroscopic studies.Phosphorylation of G protein-coupled receptor kinase 1 (GRK1) is regulated by light but independent of phototransduction in rod photoreceptors.G protein-coupled receptors--recent advancesThe functional cycle of visual arrestins in photoreceptor cells.G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs).G protein-coupled receptor kinases: more than just kinases and not only for GPCRsC-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptorChemistry and biology of visionThe origin and evolution of G protein-coupled receptor kinases.G Protein-Coupled Receptor Kinase 2 (GRK2) and 5 (GRK5) Exhibit Selective Phosphorylation of the Neurotensin Receptor in Vitro.Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4Crystal Structure of G Protein-coupled Receptor Kinase 5 in Complex with a Rationally Designed InhibitorStructure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.Substrate-induced changes in the dynamics of rhodopsin kinase (G protein-coupled receptor kinase 1).
P2860
Q24293431-F2F211A6-1B33-4AC2-AB5B-19283A4868A6Q24296928-369859CB-A5A7-4D0B-9650-BB7479A87DEDQ26774837-95D1835B-299B-43C3-BF3F-A29796AA1D3BQ27659470-F9243923-E484-409C-BCE1-C0C2E93649A2Q27666718-214FD4B9-48AB-4FB1-BE96-EF5BE83DC066Q27667904-08EAF95B-964B-4684-AABE-34C9EEC9DF5AQ27680520-0A21692B-F5B1-499A-B50D-F35395EE9975Q27680587-BCFAD6ED-3D75-4275-879C-3DF9A1CE8555Q27681072-CD23290F-CC01-47F9-A443-3C4A79DD91DEQ27681349-6EA49F4F-BCB2-44EB-BA1D-00D6788A3EFEQ27684885-FCB30581-10C1-4F1C-AD7A-17931FFB5854Q28237034-77DEF21F-9292-45CD-A789-37958AF93368Q28262711-0B48E5E0-9B90-440B-B29B-03CA5389B65FQ30368025-4ED1D460-9804-4836-B59E-CC72D014C7A0Q33581960-2F72165D-DE6C-4BDC-9A3B-AF9988F45A31Q33613404-DEFD97C0-89CE-4480-8806-9EF994F68326Q33779660-2EAF58E2-7699-4D00-B801-9EEEA8458818Q33811984-7CEEAE1C-EFAE-44D2-A48C-619EC12BED57Q34139164-20E6D71C-9410-43D4-AE73-A2BB74C224D5Q34355542-056AC003-D398-41D8-B2FF-033CD20C486CQ34462304-5F21F9AB-7187-43CB-8167-3ACB1CD5D121Q34489038-593C758D-56ED-41A0-A1A6-AE203488C165Q34624051-FD023245-615F-4DA2-A70A-DD82B8E07B55Q34723197-12F9C375-1642-4CE9-9B1C-523AF53E29F5Q34980028-CE800DB3-4C76-47AC-B4E6-79665A076F69Q34992323-8E581EAB-7AE3-4DAA-B201-C5E56BFAED94Q35054126-29BA7080-9352-4470-A28A-75127FB487A8Q35063321-121A8077-29C5-4BE1-9158-A68D2EDFAD7AQ35065927-15B7E068-00B0-4B46-8F7E-3AAC88F89331Q35387361-3D98AE8D-74C6-4B16-901F-C5A8D123A21BQ35536256-55E44A8D-22D3-41E6-B5F9-F7D344DE5AE6Q35621624-E57C260E-A02E-4DF3-9FD7-2D2D4A7B3CA1Q35626307-A7E0CBE1-CD71-4AEB-A5CC-076E69E89F58Q35693906-80C1548F-39A2-46E9-BD90-8C885E09FA3FQ35839976-F27A2F9E-F2EB-43B0-8A51-8255D37129E7Q35881875-E877E568-58AA-46FF-8503-FD76A2FBFEE4Q35953146-67AF953C-4481-40D8-8EBF-3FD2D2C64E54Q35978165-74BE8605-C65A-4D06-A91F-5C828FB3EB48Q35981205-015D366F-7CFB-4F89-BB78-5BEC5D4B58C5Q36173913-49033F59-56BA-4156-A47E-8B973C330D74
P2860
Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structures of rhodopsin kinase ...... led receptor kinase activation
@ast
Structures of rhodopsin kinase ...... led receptor kinase activation
@en
Structures of rhodopsin kinase ...... led receptor kinase activation
@nl
type
label
Structures of rhodopsin kinase ...... led receptor kinase activation
@ast
Structures of rhodopsin kinase ...... led receptor kinase activation
@en
Structures of rhodopsin kinase ...... led receptor kinase activation
@nl
altLabel
Structures of Rhodopsin Kinase ...... led Receptor Kinase Activation
@en
prefLabel
Structures of rhodopsin kinase ...... led receptor kinase activation
@ast
Structures of rhodopsin kinase ...... led receptor kinase activation
@en
Structures of rhodopsin kinase ...... led receptor kinase activation
@nl
P2093
P2860
P356
P1476
Structures of rhodopsin kinase ...... led receptor kinase activation
@en
P2093
Benlian Wang
John J G Tesmer
Puja Singh
Tadao Maeda
P2860
P304
P356
10.1074/JBC.M708974200
P407
P577
2008-05-16T00:00:00Z