The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function
about
Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domainsDifferential regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalitiesMutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signalingFluorescence resonance energy transfer (FRET) as a method to calculate the dimerization strength of basic Helix-Loop-Helix (bHLH) proteinsPhosphopeptide mapping of proteins ectopically expressed in tissue culture cell linesThe bHLH Transcription Factor Hand Regulates the Expression of Genes Critical to Heart and Muscle Function in Drosophila melanogasterThe interaction between dHAND and Arix at the dopamine beta-hydroxylase promoter region is independent of direct dHAND binding to DNAThe basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimerParaxis is a basic helix-loop-helix protein that positively regulates transcription through binding to specific E-box elementsNucleolar release of Hand1 acts as a molecular switch to determine cell fateThe transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanismDaxx inhibits muscle differentiation by repressing E2A-mediated transcriptionCooperative interaction of Nkx2.5 and Mef2c transcription factors during heart developmentIntegration of CREB and bHLH transcriptional signaling pathways through direct heterodimerization of the proteins: role in muscle and testis development.Convergent evolution of gene networks by single-gene duplications in higher eukaryotes.The role of aryl hydrocarbon receptor in the pathogenesis of cardiovascular diseases.Redundant or separate entities?--roles of Twist1 and Twist2 as molecular switches during gene transcriptionCombinatorial transcriptional interaction within the cardiac neural crest: a pair of HANDs in heart formation.Target-dependent inhibition of sympathetic neuron growth via modulation of a BMP signaling pathwayRole of uterine stromal-epithelial crosstalk in embryo implantation.Gene replacement strategies to test the functional redundancy of basic helix-loop-helix transcription factor.Delta-Notch--and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factorsSpecification of jaw identity by the Hand2 transcription factorPaths through the phytochrome network.Phosphoregulation of Twist1 provides a mechanism of cell fate control.A twist of insight - the role of Twist-family bHLH factors in development.A bHLH code for cardiac morphogenesis.Hand factors as regulators of cardiac morphogenesis and implications for congenital heart defectsTwist factor regulation of non-cardiomyocyte cell lineages in the developing heart.The Id-protein family in developmental and cancer-associated pathways.Twist2 promotes kidney cancer cell proliferation and invasion by regulating ITGA6 and CD44 expression in the ECM-receptor interaction pathwayDefective Hand1 phosphoregulation uncovers essential roles for Hand1 in limb morphogenesis.Mutations within helix I of Twist1 result in distinct limb defects and variation of DNA binding affinities.Interactions between homopolymeric amino acids (HPAAs).Specific inactivation of Twist1 in the mandibular arch neural crest cells affects the development of the ramus and reveals interactions with hand2.Polymorphism, shared functions and convergent evolution of genes with sequences coding for polyalanine domains.HAND2 Target Gene Regulatory Networks Control Atrioventricular Canal and Cardiac Valve Development.The HAND1 frameshift A126FS mutation does not cause hypoplastic left heart syndrome in mice.The Rice Basic Helix-Loop-Helix Transcription Factor TDR INTERACTING PROTEIN2 Is a Central Switch in Early Anther Development.
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P2860
The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function
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2000 nî lūn-bûn
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2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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The basic helix-loop-helix tra ...... complex regulation of function
@ast
The basic helix-loop-helix tra ...... complex regulation of function
@en
The basic helix-loop-helix tra ...... complex regulation of function
@nl
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The basic helix-loop-helix tra ...... complex regulation of function
@ast
The basic helix-loop-helix tra ...... complex regulation of function
@en
The basic helix-loop-helix tra ...... complex regulation of function
@nl
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The basic helix-loop-helix tra ...... complex regulation of function
@ast
The basic helix-loop-helix tra ...... complex regulation of function
@en
The basic helix-loop-helix tra ...... complex regulation of function
@nl
P2093
P2860
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P1476
The basic helix-loop-helix tra ...... complex regulation of function
@en
P2093
A B Firulli
B A Firulli
D B Hadzic
J R McDaid
P2860
P304
P3181
P356
10.1074/JBC.M005888200
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P577
2000-10-27T00:00:00Z