Connective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesis - Wikidata - wikimedia - TriplyDB

Connective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesis

Connective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesis

http://www.wikidata.org/entity/Q24658335

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Endothelium-derived essential signals involved in pancreas organogenesis Regulation of pancreatic function by connective tissue growth factor (CTGF, CCN2)Roles for CCN2 in normal physiological processes Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets Nov/Ccn3, a novel transcriptional target of FoxO1, impairs pancreatic β-cell function Gestational diabetes mellitus resulting from impaired beta-cell compensation in the absence of FoxM1, a novel downstream effector of placental lactogen.Connective tissue growth factor is required for skeletal development and postnatal skeletal homeostasis in male mice.Isolation, characterization and potential role in beta cell-endothelium cross-talk of extracellular vesicles released from human pancreatic islets Connective tissue growth factor acts within both endothelial cells and beta cells to promote proliferation of developing beta cells.Connective tissue growth factor modulates adult β-cell maturity and proliferation to promote β-cell regeneration in mice Zebrafish mnx1 controls cell fate choice in the developing endocrine pancreas.Loss of Foxd3 results in decreased β-cell proliferation and glucose intolerance during pregnancy.Macrophages are essential for CTGF-mediated adult β-cell proliferation after injury.The role of connective tissue growth factor (CTGF/CCN2) in skeletogenesis.Vascular instruction of pancreas development.Differential regulation of embryonic and adult β cell replication.A physiological role for connective tissue growth factor in early wound healing CTGF mediates Smad-dependent transforming growth factor β signaling to regulate mesenchymal cell proliferation during palate development.The pathological role of advanced glycation end products-downregulated heat shock protein 60 in islet β-cell hypertrophy and dysfunction Pancreas cell fate.Connective tissue growth factor (CTGF/CCN2) negatively regulates BMP-2 induced osteoblast differentiation and signaling.Targeting connective tissue growth factor (CTGF) in acute lymphoblastic leukemia preclinical models: anti-CTGF monoclonal antibody attenuates leukemia growth.miR-18a counteracts AKT and ERK activation to inhibit the proliferation of pancreatic progenitor cells Tissue engineering 2.0: guiding self-organization during pluripotent stem cell differentiation.The pivotal role of CCN2 in mammalian palatogenesis Role of CCN5 (WNT1 inducible signaling pathway protein 2) in pancreatic islets.Yap1 plays a protective role in suppressing free fatty acid-induced apoptosis and promoting beta-cell survival.Intra-islet endothelial cell and β-cell crosstalk: Implication for islet cell transplantation.A CCR2+ myeloid cell niche required for pancreatic β cell growth.Strategies for blocking the fibrogenic actions of connective tissue growth factor (CCN2): From pharmacological inhibition in vitro to targeted siRNA therapy in vivo.Connective tissue growth factor in tumor pathogenesis.Connective tissue growth factor is critical for proper β-cell function and pregnancy-induced β-cell hyperplasia in adult mice Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function.The skeletal site-specific role of connective tissue growth factor in prenatal osteogenesis.Connective Tissue Growth Factor Transgenic Mouse Develops Cardiac Hypertrophy, Lean Body Mass and Alopecia.Design and Analysis of CCN Gene Activity Using CCN Knockout Mice Containing LacZ Reporters.Vascular-derived connective tissue growth factor (Ctgf) is critical for pregnancy-induced β cell hyperplasia in adult mice.Connective Tissue Growth Factor Transgenic Mouse Develops Cardiac Hypertrophy, Lean Body Mass and Alopecia.Signals in the pancreatic islet microenvironment influence β-cell proliferation.β-Cell dedifferentiation, reduced duct cell plasticity, and impaired β-cell mass regeneration in middle-aged rats.

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P2860

Connective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesis

http://www.wikidata.org/entity/Q24658335

description

2009 nî lūn-bûn

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2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Connective tissue growth facto ...... iferation during embryogenesis

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Connective tissue growth facto ...... iferation during embryogenesis

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Connective tissue growth facto ...... iferation during embryogenesis

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Connective tissue growth facto ...... iferation during embryogenesis

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Connective tissue growth facto ...... iferation during embryogenesis

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Connective tissue growth facto ...... iferation during embryogenesis

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Connective tissue growth facto ...... iferation during embryogenesis

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Connective tissue growth facto ...... iferation during embryogenesis

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Connective tissue growth facto ...... iferation during embryogenesis

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Molecular Endocrinology

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Connective tissue growth facto ...... iferation during embryogenesis

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P2093

David M Valenzuela

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David R Brigstock

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George D Yancopoulos

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Karen M Lyons

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Laura A Crawford

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Maureen Gannon

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Michelle A Guney

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R Andrea Deyoung

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Young Ah Oh

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P2860

Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo

Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes

Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development

Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1

The evolutionarily conserved BMP-binding protein Twisted gastrulation promotes BMP signalling

Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: roles in the adhesion and migration of putative endocrine progenitor cells

Effect of connective tissue growth factor (CCN2/CTGF) on proliferation and differentiation of mouse periodontal ligament-derived cells.

Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus

Gene expression profiling of a mouse model of pancreatic islet dysmorphogenesis

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

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324-336

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4912396

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10.1210/ME.2008-0045

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3

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23

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Aris Economides

Andrew J Murphy

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2009-01-08T00:00:00Z

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19131512

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connective tissue

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2654514

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