about
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cellsANGPTL8/betatrophin does not control pancreatic beta cell expansionCD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumorsConnective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesisGeneration of functional multipotent adult stem cells from GPR125+ germline progenitorsIn Vivo Quantitative Microcomputed Tomographic Analysis of Vasculature and Organs in a Normal and Diseased Mouse ModelTLR8 deficiency leads to autoimmunity in miceIL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestineVascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesisSlitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in miceMammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylationConditionals by inversion provide a universal method for the generation of conditional allelesRegulation of the germinal center response by microRNA-155Abnormal response to stress and impaired NPS-induced hyperlocomotion, anxiolytic effect and corticosterone increase in mice lacking NPSR1.The transcription factor NFATc2 controls IL-6-dependent T cell activation in experimental colitisIdentification of surrogate agonists for the human FPRL-1 receptor by autocrine selection in yeast.Resistance to diet-induced obesity in mice globally overexpressing OGH/GPB5Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice.EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties.Role of the leucine-rich repeat domain of cryopyrin/NALP3 in monosodium urate crystal-induced inflammation in mice.Angiomodulin is a specific marker of vasculature and regulates vascular endothelial growth factor-A-dependent neoangiogenesis.Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivoHuman IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lungAngiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor.Puromycin-sensitive aminopeptidase limits MHC class I presentation in dendritic cells but does not affect CD8 T cell responses during viral infections.GPR17 gene disruption does not alter food intake or glucose homeostasis in mice.Alteration of developmental and pathological retinal angiogenesis in angptl4-deficient mice.Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutationsResistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibilityMice completely lacking immunoproteasomes show major changes in antigen presentationANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys.In-silico discovery of cancer-specific peptide-HLA complexes for targeted therapyANGPTL4-αvβ3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2.Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammationC9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice.Use of the Fluidigm C1 platform for RNA sequencing of single mouse pancreatic islet cells.Inactivating Variants in ANGPTL4 and Risk of Coronary Artery DiseaseUnique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor alpha1 chain.Alternatively activated macrophage-derived RELM-{alpha} is a negative regulator of type 2 inflammation in the lung.Ric-8 proteins are molecular chaperones that direct nascent G protein α subunit membrane association
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Andrew J Murphy
@ast
Andrew J Murphy
@en
Andrew J Murphy
@es
Andrew J Murphy
@nl
Andrew J Murphy
@sl
type
label
Andrew J Murphy
@ast
Andrew J Murphy
@en
Andrew J Murphy
@es
Andrew J Murphy
@nl
Andrew J Murphy
@sl
prefLabel
Andrew J Murphy
@ast
Andrew J Murphy
@en
Andrew J Murphy
@es
Andrew J Murphy
@nl
Andrew J Murphy
@sl
P106
P21
P31
P496
0000-0003-4152-4081