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alpha-Methylacyl-CoA racemase: expression levels of this novel cancer biomarker depend on tumor differentiation

alpha-Methylacyl-CoA racemase: expression levels of this novel cancer biomarker depend on tumor differentiation

http://www.wikidata.org/entity/Q24669748

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Molecular pathology of prostate cancer Quantitative determination of expression of the prostate cancer protein alpha-methylacyl-CoA racemase using automated quantitative analysis (AQUA): a novel paradigm for automated and continuous biomarker measurements Can p503s, p504s and p510s gene expression in peripheral-blood be useful as a marker of prostatic cancer?Internet-based Profiler system as integrative framework to support translational research.Immunochemical Assays and Nucleic-Acid Detection Techniques for Clinical Diagnosis of Prostate Cancer Using rule-based machine learning for candidate disease gene prioritization and sample classification of cancer gene expression data Cancer biomarker discovery: the entropic hallmark.Loss of stearoyl-CoA desaturase expression is a frequent event in prostate carcinoma.Expression analysis onto microarrays of randomly selected cDNA clones highlights HOXB13 as a marker of human prostate cancer.Optimization of laser capture microdissection and RNA amplification for gene expression profiling of prostate cancer.Deletion hotspots in AMACR promoter CpG island are cis-regulatory elements controlling the gene expression in the colon.AMACR is associated with advanced pathologic risk factors in sporadic colorectal adenomas.Interrogating genomic and epigenomic data to understand prostate cancer Novel diagnostic biomarkers for prostate cancer.Discovery and clinical application of a novel prostate cancer marker: alpha-methylacyl CoA racemase (P504S).Clinicopathologic and immunohistochemical profile of ovarian metastases from colorectal carcinoma The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase.A-methylacyl-CoA racemase (AMACR) and prostate-cancer risk: a meta-analysis of 4,385 participants.Defining aggressive prostate cancer using a 12-gene model.Elevated alpha-methylacyl-CoA racemase enzymatic activity in prostate cancer.Alpha-methylacyl CoA racemase (P504S): overview and potential uses in diagnostic pathology as applied to prostate needle biopsies.α-Methylacyl-CoA racemase expression and lethal prostate cancer in the Physicians' Health Study and Health Professionals Follow-up Study Tissue microarrays: applications in urological cancer research.Significance of overexpression of alpha methylacyl-coenzyme A racemase in hepatocellular carcinoma.Multiplexed fluorescence imaging of tumor biomarkers in gene expression and protein levels for personalized and predictive medicine.Cyr61 is a potential prognostic marker for prostate cancer.In situ sequencing identifies TMPRSS2-ERG fusion transcripts, somatic point mutations and gene expression levels in prostate cancers.Development of selected reaction monitoring-MS methodology to measure peptide biomarkers in prostate cancer.Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer.Molecular cloning and preliminary analysis of the human alpha-methylacyl-CoA racemase promoter.Effects of the dual 5 alpha-reductase inhibitor dutasteride on apoptosis in primary cultures of prostate cancer epithelial cells and cell lines.Expression of the platelet-derived growth factor receptor in prostate cancer and treatment implications with tyrosine kinase inhibitors.High frequency of the SDK1:AMACR fusion transcript in Chinese prostate cancer.Prognostic value of alpha-methyl CoA racemase (AMACR) expression in renal cell carcinoma.Detection and expression of human BK virus sequences in neoplastic prostate tissues.Quadriplex model enhances urine-based detection of prostate cancer.Detection of alpha-methylacyl-coenzyme-A racemase transcripts in blood and urine samples of prostate cancer patients.Ultrasound-accelerated formalin fixation of tissue improves morphology, antigen and mRNA preservation.B-cell lymphoma 2 is associated with advanced tumor grade and clinical stage, and reduced overall survival in young Chinese patients with colorectal carcinoma.Alpha-methylacyl-CoA racemase (AMACR/P504S) protein expression in urothelial carcinoma of the upper urinary tract correlates with tumour progression

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alpha-Methylacyl-CoA racemase: expression levels of this novel cancer biomarker depend on tumor differentiation

http://www.wikidata.org/entity/Q24669748

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2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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The American Journal of Pathology

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Arul M Chinnaiyan

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Hubertus Wolter

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Juergen E Gschwend

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Mark A Rubin

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Martin Loeffler

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Ming Zhou

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Peter C Lucas

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Rainer Kuefer

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Richard E Hautmann

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Rodney L Dunn

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P2860

Purification and characterization of an alpha-methylacyl-CoA racemase from human liver

Loss of CDX2 expression and microsatellite instability are prominent features of large cell minimally differentiated carcinomas of the colon

Subcellular localization and physiological role of alpha-methylacyl-CoA racemase

Delineation of prognostic biomarkers in prostate cancer

Relational database structure to manage high-density tissue microarray data and images for pathology studies focusing on clinical outcome: the prostate specialized program of research excellence model.

P504S: a new molecular marker for the detection of prostate carcinoma.

Alpha-Methylacyl-CoA racemase: a novel tumor marker over-expressed in several human cancers and their precursor lesions.

Plasma analysis of di- and trihydroxycholestanoic acid diastereoisomers in peroxisomal alpha-methylacyl-CoA racemase deficiency.

Therapeutic options in locally defined or advanced prostate cancer.

Dietary polyunsaturated fatty acids and cancers of the breast and colorectum: emerging evidence for their role as risk modifiers.

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Sooryanarayana Varambally

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12213712

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