TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase - Wikidata - wikimedia - TriplyDB

TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase

TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase

http://www.wikidata.org/entity/Q24671634

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Biological sex and mechanisms of ischemic brain injury TRPM2 links oxidative stress to NLRP3 inflammasome activation TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration Permeation, regulation and control of expression of TRP channels by trace metal ions Adenine Dinucleotide Second Messengers and T-lymphocyte Calcium Signaling Targeting TRPM2 in ROS-Coupled Diseases Sex differences in mitochondrial (dys)function: Implications for neuroprotection Structure/function analysis of PARP-1 in oxidative and nitrosative stress-induced monomeric ADPR formation.Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage.Sex stratified neuronal cultures to study ischemic cell death pathways Transient receptor potential melastatin 2: a novel target for treatment of gout.Cellular functions of transient receptor potential channels.Methionine sulfoxide reductase B1 (MsrB1) recovers TRPM6 channel activity during oxidative stress Role of TRPM2 in H(2)O(2)-induced cell apoptosis in endothelial cells.Poly(ADP-ribose)glycohydrolase is an upstream regulator of Ca2+ fluxes in oxidative cell death Alteration of poly(ADP-ribose) metabolism affects murine sperm nuclear architecture by impairing pericentric heterochromatin condensation.Poly(ADP-ribose) metabolism is essential for proper nucleoprotein exchange during mouse spermiogenesis A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α.The key role of transient receptor potential melastatin-2 channels in amyloid-β-induced neurovascular dysfunction.H2O2-induced Ca2+ influx and its inhibition by N-(p-amylcinnamoyl) anthranilic acid in the beta-cells: involvement of TRPM2 channels.Acute action of rotenone on nigral dopaminergic neurons--involvement of reactive oxygen species and disruption of Ca2+ homeostasis.Role of reactive oxygen species and redox in regulating the function of transient receptor potential channels.Sex differences in neuroprotection provided by inhibition of TRPM2 channels following experimental stroke.Redox signal-mediated sensitization of transient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions.TRPM7 and TRPM2-Candidate susceptibility genes for Western Pacific ALS and PD?Long-lasting neuroprotection and neurological improvement in stroke models with new, potent and brain permeable inhibitors of poly(ADP-ribose) polymerase.ADP-Ribose Activates the TRPM2 Channel from the Sea Anemone Nematostella vectensis Independently of the NUDT9H Domain.Oxidative stress and NAD+ in ischemic brain injury: current advances and future perspectives.Sex Steroids Do Not Modulate TRPM2-Mediated Injury in Females following Middle Cerebral Artery Occlusion(1,2,3).Particulate matter air pollution disrupts endothelial cell barrier via calpain-mediated tight junction protein degradation.Targeting TRPM2 Channels Impairs Radiation-Induced Cell Cycle Arrest and Fosters Cell Death of T Cell Leukemia Cells in a Bcl-2-Dependent Manner The long and arduous road to CRAC.Sexually dimorphic response of TRPM2 inhibition following cardiac arrest-induced global cerebral ischemia in mice Poly (ADP-ribose) polymerases (PARPs) 1-3 regulate astrocyte activation.Androgen and PARP-1 regulation of TRPM2 channels after ischemic injury.Thiol dependent intramolecular locking of Orai1 channels.TRPM2 regulates TXNIP-mediated NLRP3 inflammasome activation via interaction with p47 phox under high glucose in human monocytic cells.Nucleophile sensitivity of Drosophila TRPA1 underlies light-induced feeding deterrence.Roles of NAD (+) , PARP-1, and Sirtuins in Cell Death, Ischemic Brain Injury, and Synchrotron Radiation X-Ray-Induced Tissue Injury.Sirtuin-2 mediates male specific neuronal injury following experimental cardiac arrest through activation of TRPM2 ion channels.

P2860

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P2860

TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase

http://www.wikidata.org/entity/Q24671634

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2004 nî lūn-bûn

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2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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TRPM2 channel opening in respo ...... of poly(ADP-ribose) polymerase

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TRPM2 channel opening in respo ...... of poly(ADP-ribose) polymerase

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TRPM2 channel opening in respo ...... of poly(ADP-ribose) polymerase

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TRPM2 channel opening in respo ...... of poly(ADP-ribose) polymerase

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TRPM2 channel opening in respo ...... of poly(ADP-ribose) polymerase

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TRPM2 channel opening in respo ...... of poly(ADP-ribose) polymerase

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British Journal of Pharmacology

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TRPM2 channel opening in respo ...... of poly(ADP-ribose) polymerase

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P2093

Christopher D Benham

http://www.w3.org/2001/XMLSchema#string

Elena Fonfria

http://www.w3.org/2001/XMLSchema#string

Ian C B Marshall

http://www.w3.org/2001/XMLSchema#string

Izzy Boyfield

http://www.w3.org/2001/XMLSchema#string

Jane P Hughes

http://www.w3.org/2001/XMLSchema#string

Jason D Brown

http://www.w3.org/2001/XMLSchema#string

Kerstin Hill

http://www.w3.org/2001/XMLSchema#string

Shaun McNulty

http://www.w3.org/2001/XMLSchema#string

Stephen D Skaper

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brain

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

Role and regulation of TRP channels in neutrophil granulocytes

LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death

Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice

The world according to PARP.

The therapeutic potential of poly(ADP-ribose) polymerase inhibitors.

Poly(ADP-ribosyl)ation enzyme-1 as a target for neuroprotection in acute central nervous system injury.

Poly(ADP-ribose) polymerase: a molecular nick-sensor.

A novel TRPM2 isoform inhibits calcium influx and susceptibility to cell death.

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186-92

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586409

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10.1038/SJ.BJP.0705914

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1

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143

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15302683

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