Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage. - Wikidata - wikimedia - TriplyDB

Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage.

Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage.

http://www.wikidata.org/entity/Q33598840

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Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis New strategies to maximize therapeutic opportunities for NAMPT inhibitors in oncology Fluorescent protein biosensors applied to microphysiological systems ARTD1 (PARP1) activation and NAD(+) in DNA repair and cell death Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1 PDGFRα up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation.ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion.Alkylation sensitivity screens reveal a conserved cross-species functionome.HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β Mitochondria, energetics, epigenetics, and cellular responses to stress.Poly(ADP-ribose)glycohydrolase is an upstream regulator of Ca2+ fluxes in oxidative cell death Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage.15-Hydroxyprostaglandin dehydrogenase generation of electrophilic lipid signaling mediators from hydroxy ω-3 fatty acids.Increased PARP-1 association with DNA in alkylation damaged, PARP-inhibited mouse fibroblasts.Enzyme mechanism-based, oxidative DNA-protein cross-links formed with DNA polymerase β in vivo Transcriptional profiling reveals elevated Sox2 in DNA polymerase ß null mouse embryonic fibroblasts.A human liver microphysiology platform for investigating physiology, drug safety, and disease models XRCC1 and base excision repair balance in response to nitric oxide Synthesis and characterization of DNA minor groove binding alkylating agents Nutrient deprivation regulates DNA damage repair in cardiomyocytes via loss of the base-excision repair enzyme OGG1.Targeting DNA polymerase ß for therapeutic intervention.The strategy for enhancing temozolomide against malignant glioma.Advances and challenges in the molecular biology and treatment of glioblastoma-is there any hope for the future?Cross-species Functionome analysis identifies proteins associated with DNA repair, translation and aerobic respiration as conserved modulators of UV-toxicity.UBE3B Is a Calmodulin-regulated, Mitochondrion-associated E3 Ubiquitin Ligase.Constrained Inversion and Spectral Unmixing in Multispectral Optoacoustic Tomography.Regulation of DNA Alkylation Damage Repair: Lessons and Therapeutic Opportunities.Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis.Genome instability caused by a germline mutation in the human DNA repair gene POLB.Base excision repair imbalance in colorectal cancer has prognostic value and modulates response to chemotherapy Developing an in silico model of the modulation of base excision repair using methoxyamine for more targeted cancer therapeutics.DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade.

P2860

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P2860

Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage.

http://www.wikidata.org/entity/Q33598840

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

Bioenergetic metabolites regul ...... ath in response to DNA damage.

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Bioenergetic metabolites regul ...... ath in response to DNA damage.

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Bioenergetic metabolites regul ...... ath in response to DNA damage.

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Bioenergetic metabolites regul ...... ath in response to DNA damage.

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Bioenergetic metabolites regul ...... ath in response to DNA damage.

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Bioenergetic metabolites regul ...... ath in response to DNA damage.

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Molecular Cancer Research

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Bioenergetic metabolites regul ...... ath in response to DNA damage.

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P2093

Ashley R Brown

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Claudette M St Croix

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David Svilar

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Elena Jelezcova

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Eva M Goellner

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Jiang-bo Tang

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Ram N Trivedi

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Robert W Sobol

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Xiao-hong Wang

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P2860

HMGB1 is a cofactor in mammalian base excision repair

Ubiquitin ligase ARF-BP1/Mule modulates base excision repair

SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1

Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?

TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

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1

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2808464

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