The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines
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Ca2+-activated K+ channels in human leukemic Jurkat T cells. Molecular cloning, biochemical and functional characterizationAn amino acid outside the pore region influences apamin sensitivity in small conductance Ca2+-activated K+ channelsThe hSK4 (KCNN4) isoform is the Ca2+-activated K+ channel (Gardos channel) in human red blood cellsTamapin, a venom peptide from the Indian red scorpion (Mesobuthus tamulus) that targets small conductance Ca2+-activated K+ channels and afterhyperpolarization currents in central neuronsFunctions of SK channels in central neuronsSK3 is an important component of K(+) channels mediating the afterhyperpolarization in cultured rat SCG neuronesClotrimazole analogues: effective blockers of the slow afterhyperpolarization in cultured rat hippocampal pyramidal neuronesThe functional role of a bicuculline-sensitive Ca2+-activated K+ current in rat medial preoptic neuronsThe SK3 subunit of small conductance Ca2+-activated K+ channels interacts with both SK1 and SK2 subunits in a heterologous expression systemSmall-Conductance Ca2+-Activated Potassium Channels Negatively Regulate Aldosterone Secretion in Human Adrenocortical Cells.The relationship between functional inhibition and binding for K(Ca)2 channel blockersMolecular and cellular basis of small--and intermediate-conductance, calcium-activated potassium channel function in the brain.Effect of genistein on native epithelial tissue from normal individuals and CF patients and on ion channels expressed in Xenopus oocytesCharacterization of an apamin-sensitive small-conductance Ca(2+)-activated K(+) channel in porcine coronary artery endothelium: relevance to EDHFSmall-conductance Ca2+-activated potassium type 2 channels regulate the formation of contextual fear memory.Calcium-activated potassium channels: multiple contributions to neuronal function.Pharmacological properties and functional role of Kslow current in mouse pancreatic beta-cells: SK channels contribute to Kslow tail current and modulate insulin secretionProtection against cardiac injury by small Ca(2+)-sensitive K(+) channels identified in guinea pig cardiac inner mitochondrial membraneSarcoplasmic reticulum function in smooth muscle.K(Ca)2 and k(ca)3 channels in learning and memory processes, and neurodegeneration.Depletion of SK1 channel subunits leads to constitutive insulin secretion.Domain analysis of the calcium-activated potassium channel SK1 from rat brain. Functional expression and toxin sensitivity.Small conductance Ca2+-activated K+ channels formed by the expression of rat SK1 and SK2 genes in HEK 293 cells.Design and characterization of a highly selective peptide inhibitor of the small conductance calcium-activated K+ channel, SkCa2.Inhibition of slow Ca(2+)-activated K(+) current by 4-aminopyridine in rat hippocampal CA1 pyramidal neurones.The calcium-activated slow AHP: cutting through the Gordian knot.Preferential assembly of heteromeric small conductance calcium-activated potassium channels.Enhancement of hippocampal pyramidal cell excitability by the novel selective slow-afterhyperpolarization channel blocker 3-(triphenylmethylaminomethyl)pyridine (UCL2077).Medium afterhyperpolarization and firing pattern modulation in interneurons of stratum radiatum in the CA3 hippocampal region.K+ currents generated by NMDA receptor activation in rat hippocampal pyramidal neurons.Differential regulation of SK and BK channels by Ca(2+) signals from Ca(2+) channels and ryanodine receptors in guinea-pig urinary bladder myocytes.SK4/IK1-like channels mediate TEA-insensitive, Ca2+-activated K+ currents in bovine parotid acinar cells.Expression of postsynaptic Ca2+-activated K+ (SK) channels at C-bouton synapses in mammalian lumbar -motoneurons.Urinary bladder instability induced by selective suppression of the murine small conductance calcium-activated potassium (SK3) channel.Relationships between intracellular calcium and afterhyperpolarizations in neocortical pyramidal neurons.Firing properties and connectivity of neurons in the rat lateral central nucleus of the amygdala.SK (KCa2) channels do not control somatic excitability in CA1 pyramidal neurons but can be activated by dendritic excitatory synapses and regulate their impact.The SK channel blocker apamin inhibits slow afterhyperpolarization currents in rat gonadotropin-releasing hormone neurones.Long-lasting hyperpolarization underlies seizure reduction by low frequency deep brain electrical stimulation.Apamin induces plastic changes in hippocampal neurons in senile Sprague-Dawley rats.
P2860
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P2860
The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines
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2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2000 թվականի փետրվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
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2000年論文
@zh-mo
2000年論文
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2000年论文
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name
The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines
@ast
The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines
@en
The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines
@nl
type
label
The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines
@ast
The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines
@en
The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines
@nl
prefLabel
The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines
@ast
The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines
@en
The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines
@nl
P2860
P356
P1476
The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines
@en
P2093
P2860
P304
P356
10.1038/SJ.BJP.0703111
P407
P577
2000-02-01T00:00:00Z