Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression - Wikidata - wikimedia - TriplyDB

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression

http://www.wikidata.org/entity/Q24679740

about

Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis Polyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related Diseases Recoupling the cardiac nitric oxide synthases: tetrahydrobiopterin synthesis and recycling Nitric oxide synthases in heart failure Nitric oxide, oxidative stress, and p66Shc interplay in diabetic endothelial dysfunction Statins as regulators of redox state in the vascular endothelium: beyond lipid lowering Targeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular Diseases Maintenance of endothelial guanosine triphosphate cyclohydrolase I ameliorates diabetic nephropathy.NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy.Identification and functional characterization of phosphorylation sites on GTP cyclohydrolase I Isolation, purification, and identification of an important pigment, sepiapterin, from integument of the lemon mutant of the silkworm, Bombyx mori Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load.Tetrahydrobiopterin, superoxide, and vascular dysfunction.Transgenic overexpression of GTP cyclohydrolase 1 in cardiomyocytes ameliorates post-infarction cardiac remodeling.Endothelial dihydrofolate reductase: critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications.Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus.Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes.Molecular insights and therapeutic targets for diabetic endothelial dysfunction.Systemic and vascular oxidation limits the efficacy of oral tetrahydrobiopterin treatment in patients with coronary artery disease.Inflammatory monocytes determine endothelial nitric-oxide synthase uncoupling and nitro-oxidative stress induced by angiotensin II Endothelial nitric oxide synthase transgenic models of endothelial dysfunction GTP cyclohydrolase I/BH4 pathway protects EPCs via suppressing oxidative stress and thrombospondin-1 in salt-sensitive hypertension.Reduction of radiation-induced vascular nitrosative stress by the vitamin E analog γ-tocotrienol: evidence of a role for tetrahydrobiopterin.Enhanced oxidative stress impairs cAMP-mediated dilation by reducing Kv channel function in small coronary arteries of diabetic rats.Endothelial cellular senescence is inhibited by nitric oxide: implications in atherosclerosis associated with menopause and diabetes Gender bias in gastroparesis: is nitric oxide the answer?Modeling of biopterin-dependent pathways of eNOS for nitric oxide and superoxide production.Suppression of eNOS-derived superoxide by caveolin-1: a biopterin-dependent mechanism Differential effects of eNOS uncoupling on conduit and small arteries in GTP-cyclohydrolase I-deficient hph-1 mice.PPAR-α Agonist Fenofibrate Upregulates Tetrahydrobiopterin Level through Increasing the Expression of Guanosine 5'-Triphosphate Cyclohydrolase-I in Human Umbilical Vein Endothelial Cells.Free radicals and redox signalling in cardiovascular disease.Novel strategies to ameliorate radiation injury: a possible role for tetrahydrobiopterin M2 Macrophage Polarization Mediates Anti-inflammatory Effects of Endothelial Nitric Oxide Signaling.The two faces of endothelial nitric oxide synthase in the pathophysiology of atherosclerosis.Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology.Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing.Isoflurane favorably modulates guanosine triphosphate cyclohydrolase-1 and endothelial nitric oxide synthase during myocardial ischemia and reperfusion injury in rats.Differential modulation of nitric oxide synthases in aging: therapeutic opportunities.Toll-Like Receptor 4 Promotes NO Synthesis by Upregulating GCHI Expression under Oxidative Stress Conditions in Sheep Monocytes/Macrophages

P2860

Q24657323-DDDBA0D0-5A04-4C22-ADDD-8AA7AB8B6D8B Q26800956-561A594A-F371-4C5B-8140-C1EC5AAD7920 Q26822833-A1EF05AC-D097-4F88-88EF-8BC352DB037E Q26830146-2A8CB5B6-D748-4E45-8B32-01FBDBC2B45D Q26830607-F11DDB7E-5502-4627-AD53-01E9F2BDA3AC Q26853120-750B7934-12BF-42EA-BF80-FECD6F7C1668 Q28073279-FF36C639-B7E9-4FA9-ADBF-6FDE456FF3A8 Q30541115-C2632512-D020-4ABA-B697-1C6EFC8037C8 Q31145647-BBCED02E-54E1-41BC-8C96-282200878B66 Q33559827-55FAA0AF-4AB4-45B5-BDE5-0389A13A9741 Q33571329-1F8AA6DE-A127-4A6B-9030-1C9366F6EE4E Q33743649-523BFAC0-D8CE-4657-B89A-E5884C6F566D Q33779913-BFB9A16C-2C9B-4A95-A16F-287383A5223D Q33780119-EA4412BE-05F6-4C34-AC0E-E89C16D4BA69 Q33863119-3066A99B-4CB9-42DF-8B96-D9C656F29FC9 Q33901576-07FD2CB1-2A25-43FB-B2C2-306164D31FE9 Q33929661-2A6E0202-FA9F-4E8F-9742-3FCCA38CA296 Q33940901-5B116D3A-68E4-4761-872B-2A605C27C164 Q34022332-E5B14A4C-59D2-4A1B-BD74-415CBB69F080 Q34252918-8C5EFA12-CB6A-4E5A-A211-3DF24924CFA4 Q34283413-42752515-088E-4DC3-A9D6-12EF847D5702 Q34286604-DD5DB7CE-8834-49CA-B24D-515A8B2C5663 Q34413885-0E502054-B002-4F31-BFEA-78F72AB8DC69 Q34504618-1997D32F-CA44-403D-BE8D-7729A9348463 Q34558249-B871E0B5-8CAE-4597-93A6-0DE633EA7059 Q35118818-CECFAF06-DFAB-4E0A-80E2-09ADEBAFACCD Q35206849-FB5D4959-00AD-4730-843E-BA80BCA3E357 Q35252245-736A4978-F737-4B69-A25E-B25D4B2DA9B4 Q35315250-57079EE2-D952-4E00-AC4F-2E10E3947E14 Q35601395-C6C5554B-D559-484A-A77C-6F8CD81EDB07 Q35608768-EC66E44E-242B-4E91-9EF4-8267B27D5626 Q35745853-3303EA91-F8A2-4A59-91BD-2E7FF0555DE6 Q35848552-7ECDAC2F-D4F7-4DAC-8ECF-9818BD11974E Q35881718-CD43A904-CE7D-456D-8802-81060F49B3CC Q35888589-76460DB8-F3FA-4F6D-B29A-2B5E4AE0ED6D Q35913809-E4C57FCC-6FC7-4984-A17A-EEA3BCA642A7 Q35947546-A26F31E1-1C98-4AAB-85DD-884E34E22B9C Q35977477-B3D321CE-2C98-4FC7-8491-A4804B164846 Q36056243-F553893F-A0A6-4599-9446-CF06FAE97AAE Q36241519-8AF528D8-0021-48EA-97DF-F65E9E3EC785

P2860

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression

http://www.wikidata.org/entity/Q24679740

description

2003 nî lūn-bûn

@nan

2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

Tetrahydrobiopterin-dependent ...... yclohydrolase I overexpression

@ast

Tetrahydrobiopterin-dependent ...... yclohydrolase I overexpression

@en

Tetrahydrobiopterin-dependent ...... yclohydrolase I overexpression

@nl

type

label

Tetrahydrobiopterin-dependent ...... yclohydrolase I overexpression

@ast

Tetrahydrobiopterin-dependent ...... yclohydrolase I overexpression

@en

Tetrahydrobiopterin-dependent ...... yclohydrolase I overexpression

@nl

prefLabel

Tetrahydrobiopterin-dependent ...... yclohydrolase I overexpression

@ast

Tetrahydrobiopterin-dependent ...... yclohydrolase I overexpression

@en

Tetrahydrobiopterin-dependent ...... yclohydrolase I overexpression

@nl

P1433

Q24679740-2F1860FD-49D7-4A8C-BB69-0CD4D28A181E

P1476

Q24679740-341864EA-0F82-4C3D-8AEE-010D6F108C0D

P2093

Q24679740-14A02B13-5391-4735-838F-30E6536E23FE

Q24679740-24649999-B531-4822-9840-3C96B600C0E5

Q24679740-9CE3B331-326E-4507-990B-9B340EBA1FAE

Q24679740-B570BA92-E0B7-47B3-BB3B-32470EB566CC

Q24679740-BB3974B0-5311-40E1-ABEB-88B3979D6871

Q24679740-FBA073FB-AFBE-451F-A783-35C382727E13

Q24679740-FE5CCA41-192B-492D-B41A-79AC0DF8B808

P2860

Q24679740-02794E75-EFEA-489E-9452-7C9A86B59D7D

Q24679740-076374EA-8904-46A1-BA1A-BAE64E1B1B82

Q24679740-0A51C83B-18B3-4DE0-ACCA-D50F08F36484

Q24679740-0CDA6081-14C2-44DC-9460-C81C6B8888B8

Q24679740-11F29741-EE44-4247-A677-B5FA21309EC2

Q24679740-1AACABC8-4E84-401C-B8B2-BECF471F8C89

Q24679740-27AA26CE-0A8D-451B-8636-786D907F05A4

Q24679740-2E698874-ADFD-47CE-AB82-AFD2C6C3970E

Q24679740-2E9DAB5A-4C9A-462C-8692-2AFDBAB57B0C

Q24679740-31D3F44D-5EF1-42E5-AEE2-F0EF42A21FA8

P304

Q24679740-2315EE0A-61D0-45D1-9BB2-F963A61F6CDE

P31

Q24679740-7958FB43-484A-453F-8D9C-12B5B9E35736

P3181

Q24679740-96714A00-C9AD-4227-8DEA-3BFE5E233B03

P356

Q24679740-EDBF5296-5C8F-4A31-82F3-2931B4C8E2F9

P407

Q24679740-07DAA570-BC2D-476B-AA6E-6C05B5070B18

P433

Q24679740-DCD173ED-FFB1-4E17-B90B-87162D6F33AA

P478

Q24679740-B77ED745-1E32-443C-9ABC-07B13CA8A182

P50

Q24679740-184B6418-406C-4FEF-9CC7-F71B7D5338CD

Q24679740-F64D825D-FB94-4FEE-887D-EA6C2D6FFCF7

P577

Q24679740-E8FFFE2B-DC8C-4B4E-B70C-C0A5C8C2D99B

P698

Q24679740-A2CFD17C-59BD-4C35-A467-FBAA1F34560D

P921

Q24679740-CBE6AEAF-362A-4672-98CD-A4DAE3C521FF

Q24679740-FAA7185F-FD37-4E78-8D76-1989C926B3E1

P932

Q24679740-AAB0504C-D2E2-4F51-899F-AFE6D372F508

P3181

P356

P1433

Journal of Clinical Investigation

P1476

Tetrahydrobiopterin-dependent ...... yclohydrolase I overexpression

@en

P2093

Andrew Jefferson

http://www.w3.org/2001/XMLSchema#string

Jeffrey Khoo

http://www.w3.org/2001/XMLSchema#string

Nicholas J Alp

http://www.w3.org/2001/XMLSchema#string

Nicky Goh

http://www.w3.org/2001/XMLSchema#string

Shafi Mussa

http://www.w3.org/2001/XMLSchema#string

Shijie Cai

http://www.w3.org/2001/XMLSchema#string

Tomasz Guzik

http://www.w3.org/2001/XMLSchema#string

P2860

GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

1,25-Dihydroxyvitamin D3 induces nitric oxide synthase and suppresses growth of Mycobacterium tuberculosis in a human macrophage-like cell line

Tetrahydrobiopterin biosynthesis, regeneration and functions

Biochemistry and function of pteridine synthesis in human and murine macrophages

Abnormal biopterin metabolism is a major cause of impaired endothelium-dependent relaxation through nitric oxide/O2- imbalance in insulin-resistant rat aorta

The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: an EPR spin trapping study

Glucose-6-phosphate dehydrogenase overexpression decreases endothelial cell oxidant stress and increases bioavailable nitric oxide.

Mechanisms underlying endothelial dysfunction in diabetes mellitus.

Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin.

P304

725-35

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1105959

http://www.w3.org/2001/XMLSchema#string

P356

10.1172/JCI17786

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

112

http://www.w3.org/2001/XMLSchema#string

P50

Kirk A. Rockett

Keith M Channon

P577

2003-09-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

12952921

http://www.w3.org/2001/XMLSchema#string

P921

P932

182196

http://www.w3.org/2001/XMLSchema#string