Smad4 is critical for self-renewal of hematopoietic stem cells - Wikidata - wikimedia - TriplyDB

Smad4 is critical for self-renewal of hematopoietic stem cells

Smad4 is critical for self-renewal of hematopoietic stem cells

http://www.wikidata.org/entity/Q24679788

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Cutting the brakes on hematopoietic regeneration by blocking TGFβ to limit chemotherapy-induced myelosuppression NUP98 dysregulation in myeloid leukemogenesis Inactivation of a single copy of Crebbp selectively alters pre-mRNA processing in mouse hematopoietic stem cells.GABP controls a critical transcription regulatory module that is essential for maintenance and differentiation of hematopoietic stem/progenitor cells.Sonic hedgehog increases the skin wound-healing ability of mouse embryonic stem cells through the microRNA 200 family.Convergence of hypoxia and TGFβ pathways on cell cycle regulation in human hematopoietic stem/progenitor cells.Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome.Endothelial cells from embryonic stem cells in a chemically defined medium TGF-β signaling and its role in the regulation of hematopoietic stem cells.Plasticity and maintenance of hematopoietic stem cells during development.Multifactorial Optimizations for Directing Endothelial Fate from Stem Cells.TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy.Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7 Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells MLL5 contributes to hematopoietic stem cell fitness and homeostasis Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes.BMP4 regulates the hematopoietic stem cell niche.Smad4 restricts differentiation to promote expansion of satellite cell derived progenitors during skeletal muscle regeneration.Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs Maternal imprinting at the H19-Igf2 locus maintains adult haematopoietic stem cell quiescence.Endothelial Smad4 restrains the transition to hematopoietic progenitors via suppression of ERK activation.The role of Smad signaling in vascular and hematopoietic development revealed by studies using genetic mouse models.Mechanisms controlling hematopoietic stem cell functions during normal hematopoiesis and hematological malignancies.The role of Smad signaling in hematopoiesis and translational hematology.Cell cycle regulation in hematopoietic stem cells.Hematopoietic stem cells are regulated by Cripto, as an intermediary of HIF-1α in the hypoxic bone marrow niche.Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice.Hematopoietic stem cells, progenitor cells and leukemic stem cells in adult myeloproliferative neoplasms.Bone marrow Schwann cells induce hematopoietic stem cell hibernation.Smad4 in osteoblasts exerts a differential impact on HSC fate depending on osteoblast maturation stage.Ex vivo expansion of hematopoietic stem cells.The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease.Mechanisms of self-renewal in hematopoietic stem cells.Loss of quiescence and self-renewal capacity of hematopoietic stem cell in an in vitro leukemic niche Smad4 deficiency in T cells leads to the Th17-associated development of premalignant gastroduodenal lesions in mice.Mechanisms determining the fate of hematopoietic stem cells.TGF-β, Bone Morphogenetic Protein, and Activin Signaling and the Tumor Microenvironment.TGF-β Family Signaling in Embryonic and Somatic Stem-Cell Renewal and Differentiation.Regulation of Hematopoiesis and Hematological Disease by TGF-β Family Signaling Molecules.Deconstructing the Complexity of TGFβ Signaling in Hematopoietic Stem Cells: Quiescence and Beyond.

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P2860

Smad4 is critical for self-renewal of hematopoietic stem cells

http://www.wikidata.org/entity/Q24679788

description

2007 nî lūn-bûn

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2007 թուականի Մարտին հրատարակուած գիտական յօդուած

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2007 թվականի մարտին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Smad4 is critical for self-renewal of hematopoietic stem cells

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Smad4 is critical for self-renewal of hematopoietic stem cells

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Smad4 is critical for self-renewal of hematopoietic stem cells

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type

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Smad4 is critical for self-renewal of hematopoietic stem cells

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Smad4 is critical for self-renewal of hematopoietic stem cells

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Smad4 is critical for self-renewal of hematopoietic stem cells

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prefLabel

Smad4 is critical for self-renewal of hematopoietic stem cells

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Smad4 is critical for self-renewal of hematopoietic stem cells

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Smad4 is critical for self-renewal of hematopoietic stem cells

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P1433

Journal of Experimental Medicine

P1476

Smad4 is critical for self-renewal of hematopoietic stem cells

@en

P2093

Chu-Xia Deng

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Jennifer L Moody

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Mats Ehinger

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Sofie Singbrant

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Stefan Karlsson

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Ulrika Blank

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P2860

The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway

Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice

The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

A role for Wnt signalling in self-renewal of haematopoietic stem cells

P304

467-74

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10.1084/JEM.20060465

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3

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204

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Göran Karlsson

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6454455

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17353364

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2137898

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